Genetic discovery could dramatically reduce need for liver transplants in children
...irth. Its cause has been unknown. Symptoms include unexplained jaundice, dark urine, clay-colored stools and weight loss. The disease destroys bile ducts in the liver, trapping bile, rapidly causing damage to liver cells and severe scarring. Biliary atresia accounts for up to 50 percent of children who undergo...From science fiction to reality: Nanomedicine brings fresh hope to the medical world
...public might actually reject the technology due to unexplained fears and worries....FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
...ot be taken by anyone with active liver disease or unexplained persistent elevations of serum transaminases. Women who are of childbearing age (unless highly unlikely to conceive), are nursing or who are pregnant should not take VYTORIN. Selected cautionary information for VYTORIN Muscle pain, tenderness o...It's a no-brainer: Prepare for West Nile virus
... mind in the summer and early fall when faced with unexplained neurological presentations such as encephalitis an...rodiagnostic testing be performed in patients with unexplained weakness and in those who are critically ill to rule out acute flaccid paralysis syndrome, a severe ...JCI Table of Contents, 15 July 2004
...naling thus contributing to many of the previously unexplained traits of the disease. TITLE: Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome AUTHOR CONTACT: Harry C. Dietz Johns Hopkins University School of Medicine, 720 Rutland Ave., Baltimore, MD 2120...New pulmonary hypertension guideline challenges use of common medication
...sting, the guideline recommends that patients with unexplained PAH undergo testing for connective tissue disease and HIV infection, conditions that may predispose patients to PAH. Patients who are evaluated for PAH also are advised to undergo assessment for sleep-disordered breathing, a potential independent ri...Mysterious beach closures may be linked to contaminated groundwater, study finds
...University scientists, the source of some of these unexplained pollution events may lie just a few feet below the sand, in contaminated groundwater that discharges into the surf zone, particularly during periods of extreme tides. The findings were published May 20 on the Environmental Science & Technology (ES&...Scientists find second way to kill cancer cells: Discovery opens possibilities for new therapies
...e precise cellular mechanism for this has remained unexplained up until now. To study this issue, the researchers created mouse cells that were unable to die by apoptosis. The cells were engineered to be deficient in either the tumor suppressor gene p53, the most commonly mutated gene in human cancer, or two ...Tips from the Journals of the American Society for Microbiology
... Environmental Microbiology. In the late 1990's an unexplained disease causing weakness, lethargy and slow responses to stimuli began appearing in American lobsters pulled from the Gulf of Maine. In the study, the researchers identified a group of Vibrio fluvialis-like bacteria in samples taken from sick lobste...People with undetermined muscle/bone pain tend to be severely vitamin D deficient
...re for symptoms of no known cause, most frequently unexplained back, head, arm, and leg pain. A trial to assess management of persistent, non-specific pain by prescription of vitamin D replenishment is recommended by Plotnikoff....Nanotech instruments allow first direct observations of RNA 'proofreading'
...uble helix but rather undergoes a fitful series of unexplained starts and stops. ''This enzyme is either full on or full off, as far as we can tell,'' Block said. ''It moves at about ten to 15 bases a second and pauses on average about once every 100 bases. Pausing is ubiquitous. About 97 percent are short pause...Stem cell defects are key to Hirschsprung's disease
...ossible to find the cause of some of the currently unexplained cases of Hirschsprung's disease." Other scientists have shown that neural crest cells migrate through the gut in response to a biochemical substance called GDNF or glial-derived neurotrophic factor. "Since NCSCs express higher levels of Ret, the rece...Not for women only: Osteoporosis in men
...lieves that men who are over 50 and complaining of unexplained back pain or other secondary causes such as history of kidney stones, alcoholism, and steroids usage, should be screened with bone density testing. For those men they are trying to identify who have no identifiable risk factors there are no current ...Newly invented Endometrial Function Test (EFT®) solves the puzzle of unexplained infertility
...tion are believed to be the basis of many cases of unexplained infertility in women. A normal healthy endometrium...d Kliman. "This is what happens in many women with unexplained infertility. The EFT can diagnose this problem and help guide the infertility specialist to fix the ...Women are more likely to suffer recurrent miscarriages if their first child is a boy
...ubsequent miscarriages, but for women who suffered unexplained secondary recurrent miscarriages (SRM) it could me...come of subsequent pregnancies among patients with unexplained secondary recurrent miscarriages. [1] " He studied 204 SRM patients admitted to clinics between 1986...New mouse virus may help scientists better understand cruise ship epidemics
...in also suggests that other scientists investigate unexplained deaths in immune-deficient mice. "It may reveal other new viruses that might be useful for studying human biology and human infectious disease," he says....The nucleus: Not just a bag of chromosomes
...reciated that these proteins are doing unexpected, unexplained things." Subsequently, lamin A has been linked to five other diseases, affecting the skeleton, heart, brain and fat, notes Wilson. Beyond lamins, there's an emerging revolution in understanding cell division, says Wilson. While the general cycle...Sex and gender scientists explore a revolution in evolution
...in the long run. Homosexual behavior is common but unexplained by Darwin. Over 300 vertebrates, including monkeys, flamingoes and male sheep, practice homosexual behavior. Homosexuality in some species appears to play a social role. For instance, bonobos (pygmy chimpanzees) will have sex with same-sex partners t...Guidelines outline evaluation of children with global developmental delay
...n Rett syndrome should be considered in girls with unexplained moderate to severe developmental delay Shevell noted that while many of these disorders have no specific therapy, it is important to determine the cause of the disorder. "An accurate diagnosis has specific implications for treatment, prognosis, mana...US researchers find first conclusive evidence that lead is linked to male infertility
... sperm function and may be a contributory cause of unexplained male infertility.[2] The findings have led princip...minal plasma when evaluating men from couples with unexplained fertility. She also believes there is a case for health and safety authorities to continue re-evalua...