Evolutionary genetic tools trace cancer clone lines
...nalyze them tostudy the history of species. As the universal informational molecule, DNA sequences can be analyzed andcompared regardless of their origins. "While changes that would normallyaccumulate over millennia in normal cells accumulate over months in thesemismatch repair deficient tumor cells," says Tav...Dinosaur fossils reveal evolution's big picture, says Paul Sereno
...ditionalclassification system used to assemble the universal "tree of life." Anotherdiscusses recent progress in understanding the influences that shaped the earlyunfolding of animal diversity during an event known as the Cambrian explosion. Athird provides insight into why nature chose RNA as the fundamental ...Unique web site provides live access to laboratory research
...said. "Our World Wide Web NMRspectrometer provides universal access to real, research-gradeinstrumentation. Even untrained users can operate the system, thanks to thepopularity of Web browsers and an easy-to-use graphical layout." NMR technology and a related system known as magnetic resonance imagingallow sc...Enzyme inhibitor reduces cardiac cell death in heart attack
...or at the Medical School. Caspases are the universal effectors of programmed cell death, orapoptosis. In response to apoptotic stimuli, such as DNA damage, growth factordeprivation and stress, caspases chop up certain cell proteins and alsosequentially activate other caspases down the line to follow su...Key progress by Weizmann scientists in the race to unravel ribosomal structure
...where protein biosynthesis begins. Ribosomes, the universal cellular organelles responsible for protein production, are essential tolife. Receiving genetically encoded instructions from the cell nucleus, the ribosomal factory churnsout proteins - the body's primary component and the basis of all enzymatic rea...'Frozen pictures' allow far-reaching glimpse into the cells protein factory
...me - the cell's protein factory. Ribosomes, the universal cellular organelles responsible for protein production, are essential to life. Receiving genetically encoded instructions from the cell nucleus, the ribosomal factory churns out proteins - the body's primary component and the basis of all enzymatic r...Meet the chemical that lets sea creatures thrive
...en though humans don't have TMAO, it seems to be a universal stabiliser," says Yancey. "Theidea is that it could be used medically also to work on all sorts of proteins."...Scientists figure out how cells' tiniest motors work
...wered by ATP, the chemical that serves as a nearly universal energy source inside cells. Two kinesin motors work as a coordinated team to pull their cargo, one motor just ahead of theother on the tracks. In the crucial, repeating step described in the Nature report, the thrustingmovement of the lead motor's ...AAAS statement on genetic discrimination
... 8, 2000 -- Genetic variation among individuals, a universal fact oflife with great potential for scientific and social advances, should never be used as a tool fordiscrimination, the American Association for the Advancement of Science (AAAS) emphasized today. The AAAS strongly supports policies designed to pr...Common algae can be valuable source of hydrogen fuel
...c pathway, which generates the hydrogen and may be universal in many types of algae. "They're utilizing stored compounds and bleeding hydrogen just to survive," Melis said. "It's probably an ancient strategy that the organism developed to live in sulfur-poor anaerobic conditions." He said the alga culture ......ion of telomerase, and we think this is probably a universal kind of feature of telomerase," says Blackburn. The finding also adds weight to recent evidence that the RNA component of HIV, traditionally disregarded in retroviral therapies as passive, plays an integral role in HIV replication, and it therefore...Gene responsible for aging found in yeast
...ur findings thus provide a model for aging that is universal and explains how calorie restriction extends life span," says Dr. Guarente. "We believe that these studies could lead to the development of a drug that intervenes to strengthen the Sir2-silencing process and provides the benefits of calorie restrict......oach of looking for fundamental ways to understand universal features of the protein-folding process using simple principles is complementary to the biochemical approach of developing a tightly focused and detailed understanding of the structure of proteins. "There may be some value to looking at the same thi...Scientists unravel ancient evolutionary history of photosynthesis
...nts their common ancestor, usually regarded as the universal ancestral cell. This change in perspective is necessary because gene-swapping was common among ancient bacteria early in evolution. The work of Bauer's group demonstrates that scientists must study the evolution of individual metabolic processes suc...Brown researchers use wildcards to develop better way to sequence DNA
...a and Upfal want to test chemical compounds called universal bases for use as the gaps in DNA probes. A perfect universal base would attach itself to all four bases in DNA. If the universal bases behave clos...Tiny RNA may be universal regulator of developmental timing in animals
...of creatures, the team found that this RNA gene is universal to bilaterally symmetric animals (those in whom th...ental step in developmental biology. An analogous universal control gene called the homeobox, which encodes a protein that binds to DNA, was discovered in fruit...Clinton names a diverse group of researchers to receive the 2000 National Medals Of Science
...gs may be classified led to a quantitative map, or universal tree of life, by which the diversity of all life can be assessed. For chemistry, John D. Baldeschwieler of CalTech and Ralph F. Hirschmann of the University of Pennsylvania are receiving the science medal. Baldeschwieler's work in molecular assem...New discovery: 'footprint' shows master switch simultaneously controls plants' disease defenses
...ike the one we found could be a binding site for a universal switch for the immune system among many plant species," said Dr. Jeffery L. Dangl, John N. Couch associate professor of biology at UNC-CH. "This discovery, on this scale, is a first for plant biology." Working with Arabidopsis, a member of the mu...US and Japanese scientists develop new test for male infertility
...nexplained infertility. "Ubiquitin appears to be a universal marker of semen abnormalities, recognising a wide range of sperm defects and also contaminants in semen," said Dr Sutovsky. "I think SUTI could be the first truly objective assay for male infertility, based on an exact, fully automated measurement o...