Missing protein is double-edged sword in cancer development
... Normally, cancer cells are genetically unstable they tend to lose and gain chromosomes at random. This kind of activity spells death for most normal cells, but the rare cell that somehow loses its E2F3 factor and survives seems to gai...New clues emerge about the fate of smog in Sierra Nevada forests
...ved in the atmospheric reactions with ozone are so unstable that they are difficult to measure, but Goldstein said understanding such natural processes is necessary in the development of scientifically based air quality management policy. "In order to develop legislation to control the amount of aerosols in...Rumors of male chromosomes demise greatly exaggerated, study finds
... way to keep these genes coherent despite a rather unstable structure. That instability of structure could be disastrous for a particular individual, but it won't be disastrous for the Y, because the deleted Ys would not be passed on." For the study, researchers mapped the gene sequence of a Y chromosome from...UCR graduate student wins best poster at Environmental Mutagen Society Meeting
...g is: Are these changes truly representative of an unstable intermediate in the process of cervical carcinogenesis? I am trying to determine, too, if the changes can be used to identify women who are at an increased risk of developing cercival cancer." David Eastmond, Olaharski's advisor, said, "Drew's resea...Scientists map signaling molecule crucial to survival, disease
...sult. But phosphates' high energy bonds make them unstable and difficult to measure; they break off from proteins so readily that it is difficult to use mass spectrometry to determine their original locations. Shokat and Knight solved this problem by figuring out a way to transform the protein so that the pr...Modern global warming more damaging than in the past
...was crucial for the survival of species during the unstable climate of the last ice ages. However this broad movement of species, which has prevented large-scale extinctions in the past, is not likely to operate effectively in the modern world, he said. Today, human activity has reduced previously continuous......ese bubbles occur because the tip of the vortex is unstable when rotation is fast. The air bubble is usually sucked straight down the drain after detaching. The flow around the plughole itself has some unusual behavior. Most of the water on the bottom of the tub flows toward the hole but about one centimeter ...JCI Table of Contents, September 15, 2003
...ormalities including tremor, muscle stiffness, and unstable voluntary movements and posture. The main pathological feature of the Parkinson brain is the loss of dopaminergic neurons. Reported in an article in the September 15 issue of the Journal of Clinical Investigation, Przedborski and colleagues administe...... named NIPA1, NIPA2, CYFIPI, and GCP5 in the most unstable part of chromosome 15. The second paper details how researchers linked a mutation in NIPA1 to families with hereditary spastic paraplegia. "What we see here is two very important ways in which genetics can effect disease," said Nicholls. "Often inh...Purdue researchers solve decades-old corn, sorghum problem
...y also have revealed the genetic process behind an unstable variety of sorghum frequently used in commercial p...rect duplications, like the one we see in dw3, are unstable because they can self-correct," Johal said. In another phenomenon of genetics, called recombination,...Clay may have aided formation of primordial cells
...t acidic conditions induced the micelles to become unstable and somehow incorporate themselves into a growing vesicle. "After we showed that efficient growth was possible, the next problem was how to complete the cycle by persuading these vesicles to divide," said Szostak. The scientists discovered that if th...Story tips from the Department of Energy's Oak Ridge National Laboratory, November 2003
...Results from low-energy collisions of neutron-rich unstable nuclei and nickel-64 could point to the recipe for... nuclei together, in the beam. In this case it was unstable nuclei of tin-132. This approach is in sharp contrast to the conventional approach of smashing stabl...Study explores safety of low-dose radiation
...els of radiation all around us - even inside us in unstable forms of common elements such as potassium and hydrogen - cause problems and exactly what genes and proteins in the body help repair and, more importantly, prevent damage. "The reason to do this in fish is to look at mechanisms of injury and innate...Study finds evidence for global methane release about 600 million years ago
...th's history, and they are a large and exceedingly unstable source of greenhouse gas, greater than the equival...of geology at UC Riverside. "The Earth has a large unstable pool of these clathrates in ocean sediments today, and it is thought that a few degrees of ocean war...JCI table of contents, January 2, 2004
... San Francisco demonstrate that latency in KSHV is unstable and results in segregation of the viral episome. The data indicate that acquisition of stable KSHV latency is a multistep process that is successful to varying degrees in different cell types. The report also demonstrates that lytic replication is im...UF study suggests life on Earth sprang from borax minerals
...n Institute in Pasadena, Calif. "But ribose is too unstable to survive under Miller's conditions." Ribose, like most sugars, turns into tar if not handled carefully. "It is like baking a cake too long," said Benner, a UF distinguished professor of chemistry and anatomy and cell biology. In 1995, Miller gave ...New antioxidants are 100 times more effective than vitamin E
...ut they proved to be impractical because they were unstable in air. In addition to attaching a nitrogen atom to the ring, Pratt's idea was to substitute a nitrogen atom for one of the carbon atoms in the ring itself. With both substitutions he predicted that the resulting molecules, called pyridinols, should ...Awards honor Alt's three decades of genetic cancer research
...the repair process breaks down, the genome becomes unstable and cancers are more likely to develop. Alt's wi...growing and dividing. In its absence, genomically unstable cells remain in circulation and accumulate more mutations, becoming increasingly malignant. (The p5...Gene at root of urban air pollution's lung effects
...d Blood Institute and GlaxoSmithKline. Ozone is an unstable molecule comprising three oxygen atoms. Natural ozone in the upper atmosphere plays an important role in filtering out ultraviolet rays from the sun. In the lower atmosphere, however, man-made ozone pollution results from a chemical reaction with nit...New pulmonary hypertension guideline challenges use of common medication
...ommonly used treatment for high blood pressure, in unstable patients due to the potentially fatal side effects associated with the medication. PAH is a life-threatening condition that occurs when the arteries that supply blood to the lungs become constricted, limiting the blood flow to the lungs and, ultimat...