Long-term heart damage may result from constant confrontation and defeat
...tion followed by territorial stress (housing in an unstable social environment) induced myocardial fibrosis, coronary collagen deposition, increase in coronary wall-to-lumen ratio, and coronary collagen-to-vessel ratio. A New Study Most available animal studies focus on cardiac impact after ...Pump failure implicated in a form of dystonia
...o either jam the pump's molecular machinery, cause unstable misfolding in the protein, or both. The researchers tested the effects of the mutations by incorporating them into cultured cells. They found that each of the six mutations tended to kill the cultured cells. The researchers determined that the death ...Study by Tufts biologist provides window into progression of some degenerative diseases
.... Freudenreich, a molecular biologist, studies the unstable elements in the human genome, particularly the type of unstable element called "trinucleotide repeat sequences," whose expansion causes numerous human genetic disea...The telomere crisis: A crucial stage in breast cancer
...nd damage-control mechanisms kick in that kill the unstable cells. This process, known as "telomere crisis," normally protects against inappropriate long-term cell growths like cancer. Gray and his colleagues believe that "very rarely, the chromosome instability activates a specialized DNA-replication comple...Images reveal how rotavirus - leading cause of diarrhea - enters cells
... killed viruses can present safety concerns and be unstable without refrigeration. In contrast, the "head" of the VP4 protein is very stable at room temperature and easy and relatively cheap to produce, Dormitzer says; he believes the same is true of the "body." A vaccine based on these proteins could be ver...... extremely regulated set of virulence genes and an unstable genome that may explain the bacterium's ability to thwart the immune responses of its host animals mainly horses, mules and donkeys. "The combination of virulence genes and genomic instability may explain why some scientists consider this to be t...