Presence of certain tumor markers for melanoma could signal best results for vaccine
...hen received immunotherapy with CANVAXIN, a cancer vaccine (CancerVax Corp., of Carlsbad, Calif.). The tumors subsequently were analyzed for three immunogenic MAAs -- TYR, TRP-2 and MART-1 -- all contained in the cancer vaccine. To assist with their analysis, the scientists turned to a relatively new tech...Tips from the Journals of the American Society for Microbiology
Strategy for ulcer vaccine shows promise Researchers from Auburn University h...developed a strategy that may lead to an effective vaccine against a common cause of ulcers. They report their findings in the January 2003 issue of the journ...Grant funds research to develop microbicide barrier to HIV
...ery 10 years, someone reports that there will be a vaccine against AIDS within the next 10 years," said Dr. H...gainst HIV in the next seven to eight years. "Both vaccine and microbicide HIV-prevention strategies are needed," she continued. "Microbicide development has r...Price to pay for vaccinating against smallpox
... But the precaution will be costly: the contagious vaccine will sicken and almost certainly kill a few people...y not work for all adverse reactions. The smallpox vaccine will first be given to half a million US troops and a similar number of health workers. It will then...CDC Telebriefing: Smallpox educational activities and West Nile Virus update
...t Nile Virus experts WHAT: To discuss smallpox vaccine educational activities/update on smallpox vaccine plan and West Nile Virus update, respectively. Brief remarks followed by Q/A. WHEN: Thursday, De...Chicken pox vaccine OK for children with kidney disease
...en's Center report that two doses of the varicella vaccine for chicken pox given one to two months apart can ...nephrologist at the Children's Center. Varicella vaccine contains small doses of weakened strains of the chicken pox virus that activate immune system "memor...JCI table of contents, December 15, 2002
...epitope CD8+ T cell response to a NY-ESO-1 peptide vaccine results inimprecise tumor targeting CONTACT: Danila Valmori Ludwig Institute Clinical Trial Center New York Branch at Division of Medical Oncology Department of Medicine, Columbia University College of Physicians and Surgery 650 West 168th Street, B...West Nile Virus capsid protein causes encephalitic inflammation by triggering cell suicide
...ner. "In addition to the possibility of creating a vaccine for West Nile, our results support the idea that a specific portion of the capsid protein called the 3' terminal region is required for the protein's pathogenicity. If we can find a way to block that region's function, this might help slow the viru...UC Davis to begin identifying eligible families for study on environmental factors in autism
...e used to compare and contrast immune responses to vaccine antigens among the three groups. "Our ultimate goal is to understand common patterns of dysfunction in autism and clarify how toxins contribute to abnormal neurodevelopment so that we can develop rational strategies for intervention and, hopefully, p...Infection with second strain of HIV compromises treatment
... effective HIV vaccine. But they do emphasize that vaccine developers are likely to be locked in a long-term ...ts' findings may influence the direction of future vaccine development strategies, Walker cautions that patients with superinfection present unique challenges....Dispersin' Escherichia coli all over the gut
... biofilm. EAEC is a rapidly emerging pathogen, but vaccine development is in itsearliest stages. Dispersin's ...y of EAECstrains make it a potential candidate for vaccine development. Findings byNataro and colleagues that dispersin can provoke a strong immune response in...Research on lentiviruses to continue at Ohio State
...y Medicine developed the first vaccine against the feline leukemia virus the No. 2 killer of cats in the U.S -- that has protected millions of cats against this deadly disease. Ohio State and its researchers came under fire las...JCI table of contents, October 21, 2002
...ents: Bacterial infectious disease control by vaccine development CONTACT: Roy Curtiss Dept. Of Biology Washington University 1 Brookings Drive, Campus Box 1137 St. Louis, MO 63130-4899 Phone: 1: 314-935-6819 Fax: 314-935-7246 E-mail: rcurtiss@biology.wustl.edu View the PDF of this perspective serie...Alzheimer's, nutrition, smallpox, and other 'Human Health Frontiers' addressed by AAAS speakers
... eventually predict outcomes and use this data for vaccine development." Contact information on microbes: Claire Fraser, (c/o Bob Koenig) (301) 838-5880; David Relman, 650-852-3308; Rudolf Tanzi, (c/o Donna Burtanger) at (617) 432-3991....UMBI licenses HIV rat to Harlan
... transgenic technology, which will also accelerate vaccine work."...Researchers identify candidate vaccine for Sjgren syndrome
...evalent autoimmune disease, as well as a candidate vaccine to treat this condition. This research is reported...ren syndrome. They have also developed a prototype vaccine to treat this condition, which dramatically reduced the progression of tissue damage even relatively...Parasite, mosquito genomes complete malaria picture
...e strains and insecticide-resistant mosquitoes. No vaccine exists. The sequencing of P. falciparum resulted from an international collaboration established in 1996. Besides NIAID, consortium support came from the Wellcome Trust, the Burroughs Wellcome Fund and the U.S. Department of Defense. Sequencers worke...UCR scientists contribute to study that will help formulate new ways to combat malaria
...e economic cost to affected nations is immense. No vaccine has been developed for malaria and, due to a number of factors, the incidence of the disease is on the rise. Understanding the genetic makeup of the mosquito that transmits malaria will help with the design of new strategies to fight this disease." M...Scientists at TSRI identify thousands of proteins associated with deadliest form of malaria
... and gametocytes) and, thus, which might make good vaccine targets. Mass Spectrometry and Malaria The proce...side the cell--important pieces of information for vaccine design. One unexpected finding was that a lot of the proteins that were expressed in particular stag...Database lets researchers worldwide access genome of malarial parasite
...rganisms, including promising targets for drug and vaccine design. An early version of the PlasmoDB web site -- http://PlasmoDB.org -- went live in June 2000 and now receives thousands of queries a day from more than 100 countries. With release of the complete genome sequence, the Penn team expects to s...