Female hormones found to protect against harmful effects of fructose
...esponse to a fructose diet in females and examined vascular responses to insulin. The Study The authors of "...rmore, there appears to be a sex difference in the vascular actions of insulin, which may also be involved in the mechanisms responsible for the sex differences...For spinal cord injury patients, new insights for rehabilitation therapy
...ound the extent of the injury. The science behind vascular performance or blood flow is that perfusion pressure and vascular resistance govern blood flow to tissue. Because mean arterial pressure and venous pressure are norma......luding cell migration, nerve cell connections, and vascular and heart development. They are receptors with tyrosine kinase enzyme activity and are, Greenstein said, the largest class of this type of receptor in the human genome. The first tyrosine kinase receptor, the epidermal growth factor receptor, was c...Separated before birth: Molecular signals part fetal blood and lymphatic vessels
...he mechanisms by which molecular signals influence vascular development, pave the way for potential therapeutics, and may ultimately clear up a minor mystery among researchers that has been brewing since the mid-1990s. "According to our studies, the SLP-76 and Syk proteins, which we previously knew to have a...OXiGENE announces commencement of Phase I/II clinical trial of Combretastatin A4 Prodrug
...tion of a Phase I/II combination study of its lead vascular targeting agent (VTA), Combretastatin A4 Prodrug (...pounds that are designed to selectively damage the vascular structure of solid tumors. "The combination of CA4P and radiotherapy has shown a high degree of ...OXiGENE announces phase II clinical trial of lead anti-tumor compound in thyroid cancer
...the startof a Phase II clinical trial for its lead vascular targeting agent(VTA), a tumor-starving compound ca...rapy drug called Carboplatin. CA4P attacks the vascular structure of solid tumors and otherdiseases characterized by the formation of aberrant blood vessels...Global analysis finds nearly half the Earth is still wilderness
...reas," because they contain at least 1,500 endemic vascular plant species, meaning they are found nowhere else in the world. The five areas are Amazonia, the Congo Forests of Central Africa, New Guinea, the North American Deserts and the Miombo-Mopane Woodlands and Grasslands of Southern Africa. "These wilde...University of Maryland research reveals true target of calcium channel blockers
...n channels, which regulate the entry of calcium in vascular smooth muscle. The amount of calcium entry determines how much the small arteries contract to produce myogenic tone, a type of muscle contraction in blood vessels critical for the control of blood flow and blood pressure. Altered myogenic tone may pl...JCI Table of Contents, December 2, 2002
...mural-cell derived molecules in the fine-tuning of vascular networks.Thus, the association of the pericyte with the vessel accomplishes more thanlocal Ang1 delivery". A more clear understanding of the role of pericytes in the maintenance ofnormal vessel stability will be important for anti-angiogenic therapie...Hearing loss & rehab, stroke & depression among topics of Vol. 39, Iss 5, JRRD
...viduals with lower-limb amputations and peripheral vascular disease. Time-expanded speech and speech recognition in older adults Investigates the effects of speech rate on speech recognition in older adults. Eighteen adults, assigned to three different groups, were tested at two rates of time-expanded spee...Study shows first direct evidence that transplanted muscle cells can take root in damaged hearts
...ansplanted cells also appear to have begun forming vascular muscle cells, which make up the walls of blood vessels. In areas where cells had been injected, there was a significant increase in small blood vessels compared with areas that had not received injections. In addition to the encouraging finding that...UCSF celebrates opening of new vascular research laboratory
The UCSF division of vascular surgery, along with the UCSF division of biomedica...rking to generate and transfer new knowledge about vascular diseases into safer and more effective treatments. The symposium on angiogenesis the growth of ...November GEOLOGY and GSA TODAY media highlights
...9-1042. The walls of the water-conducting cells of vascular plants possess several concentric layers, each no more than a few microns thick, made up of differing concentrations of the phenolic compound lignin and of carbohydrates such as cellulose. X-ray spectromicroscopy allows imaging of the spatial distri...Branching out: New insight into vessel branching during development
...itute), has discovered that different forms of the vascular endothelial growth factor (VEGF) protein regulate ...g cells, and lays the foundation for the intricate vascular network that will support postnatal organ function. As published in the October 15th issue of Genes ...6th Annual Symposium on Biomaterial Science
...ge for discussions of their use in orthopaedic and vascular surgery, gene therapy, drug delivery, and tissue engineering. At the October 17 New Jersey Biomaterials Award dinner, the New Jersey Center for Biomaterials will recognize Stanley S. Bergen, Jr., president emeritus of the University of Medicine and ...Scientists discover role for c-myc gene in tumor angiogenesis
...s what the existing vasculature can provide, a new vascular network is established (vasculogenesis) and capill...of red blood cells. The researchers found that the vascular defects in the c-Myc-deficient mice arise from the mis-expression of intercellular signals that coor...University of Pittsburgh scientist discusses blood cell damage from biomedical devices
...c heart valves, heart-assist devices, oxygenators, vascular grafts and hemodialysis systems can help to save or significantly extend lives, these same devices also can damage the blood cells which travel through them. Severe consequences can result when blood cells are damaged or broken down, said Marina Kame...Research reveals a more complete picture of breast tissue
...cterize the stage of a tumor by learning about its vascular makeup. Different levels of blood vessel activity in a tumor influence the effectiveness of treatment, so knowing the vascularity stage of a tumor should help design better treatment regimes. During the first two and a half years of this five-year N...African-Americans more likely to lose limbs due to vascular disease than other groups
...tion department report that African Americans with vascular disease are up to four times more likely to have l...to 1997 who required lower limb amputations due to vascular disease. Patients excluded from the study sample included those who had a lower limb amputation due...UT Southwestern researchers develop vaccine against deadly bioterrorism toxin ricin
...esis, as well as the site responsible for inducing vascular leak. The latter was identified by Vitetta's group several years ago in its ongoing efforts to produce safer immunotoxins containing the A chain. Immunotoxins are anti-cancer drugs that have been used by Vitetta and her colleagues in more than 200 ca...