USC awarded $3.5 million to study DNA enzyme
...the enzyme knows when it's got the correctDNA base versus the incorrect one, and how that changes thespeed of the reaction," Warshel said. A third project led by structural biologist Samuel Wilson, deputydirector of the National Institute of Environmental HealthSciences, will provide detailed 3-D "snapshots...Fat hormone leptin alters brain architecture and activity, which in turn drives feeding behavior
...y that the brain's wiring may be different in lean versus obese individuals," Friedman added. In March 2004 the U.S. Centers for Disease Control and Prevention announced that obesity is now the second leading cause of death in the United States. Poor diet and inactivity now account for more than 400,000 de...Laboratory rat gene sequencing completed
...the disadvantages. "The issue of efficacy of WGS versus other approaches to the sequencing of large genomes remains a matter of earnest scientific debate, and methodology for producing draft sequences continues to evolve" said Dr. George Weinstock, co-director of the BCM-HGSC. Following the rat project, ...Survey reports fall in stem cell transplants for breast cancer
...allogenic transplantation induced a curative graft versus host effect in patients with a variety of blood ca...fied doses and highlighting the power of the graft versus tumour effect. This shift was now being seen in solid tumour treatment with small studies testing wh...Student creating polymers to chaperon DNA across cell membrane
...April 1, 2004. Rudisin's research looked at linear versus branched molecules in terms of chaperone ability, explains Timothy Long of Blacksburg, professor of chemistry in the College of Science at Virginia Tech. "The poster presents findings regarding the effects of polymer structures on complexation with D...NIST-led research de-mystifies origins of 'junk' DNA
... group appears to resolve a debate over the "early versus late" timing of the appearance of introns. Since introns were discovered in 1978, scientists have debated whether genes were born split (the "introns-early" view), or whether they became split after eukaryotic cells (the ones that gave rise to animal...Rockefeller University scientists take on controversial 'vibration theory' of smell
...ume, and Turin predicted that the vibration of odd versus even aldehydes would not be the same because the aldehyde group of even number aldehydes would have more freedom to rotate, producing different vibrational frequencies. But vials consisting of two odd or two even aldehydes were not perceived by parti...AIDS drug helps to keep HBV at bay during chemotherapy for breast cancer
... 17 out of 41 in the control group (seven per cent versus 41 per cent); three patients in the study group suffered from hepatitis and two from severe hepatitis (eleven and seven per cent) compared with 27 patients in the control group who developed hepatitis and six who developed severe hepatitis (66 and 15...Alcohol consumption can damage hearing
...to identify those lesions caused by alcohol itself versus those caused by other common alcohol-related factors, such as thiamin deficiency," said Elisabeth Stephanie Smith, a member of the Ear, Nose and Throat Clinic at the University of Ulm, Germany, and first author of the study. For example, she said, ...JCI table of contents, March 1 2004
.../19762.pdf ACCOMPANYING COMMENTARY: Immune system versus tumor: shifting the balance in favor of DCs and effective immunity AUTHOR CONTACT: Howard Kaufman Columbia University Medical Center, Ithaca, New York, USA. Phone: 212-342-6042 Fax: 212-342-0234 E-mail: hlk2003@columbia.edu View the PDF of this com...Final media advisory for the 4th European Breast Cancer Conference (EBCC-4)
...rst results from international study of exemestane versus tamoxifen as first-line treatment in metastatic breast cancer Thursday 18 March 13.00hrs 1. Dr Eric Winer: Rigorous testing needed for complementary and alternative therapies (CAMs) which CAMs are safe and which need further investigation? 2. Profes...Drug addiction, learning share common brain protein
...increased or decreased activity in super-sensitive versus normal mice, the team reported. The protein encoded by one of the genes -- known as postsynaptic density-95 or PSD-95 -- dropped by half in the brains of super-sensitive mice, the researchers found. The protein had never before been linked to addi...Intelligent design: The new 'big tent' for evolution's critics
...the intellectual high ground in the epic evolution versus creationism debate. At one end of the spectrum reside the "naturalistic evolutionists" who argue that life neither requires nor benefits from a divine creator. At the other pole, "scientific creationists" compress the entire history of the cosmos in...Applying results of women's health initiative study to individual patients
...ctors take the time to help them balance the risks versus the benefits of hormone replacement therapy (HRT). AAAS is the American Association for the Advancement of Science. "We're saying that physicians have to learn more about their patients' risk profile," said Susan Johnson, a gynecologist who is an inv...Breakthroughs in acoustic tracking shine new light on the lives of fish
...boundaries with long term pay-offs for the fishery versus "leaky" reserves that allow more fish to be caught in surrounding areas. While a single small reserve will not adequately protect an entire population of fish, these new results show that a network of small reserves may be just as effective in protec...Targeting hard-to-kill fungal infections
...eoformans and Histoplasma capsulatum to -Radiation versus Radioimmunotherapy with - and -Emitting Radioisotopes was written by Ekaterina Dadachova, PhD, Ruth A. Bryan, PhD and Annie Frenkel, BA, from the Department of Nuclear Medicine; Joshua D. Nosanchuk, MD from the Department of Medicine; Arturo Casadeva...Laser technology to map industrial plant gases available through Alberta Research Council
...ass emissions of compounds from an entire facility versus a small area," says Allan Chambers, research scientist with ARC's Carbon and Energy Management business unit. "We can even create two- and three-dimensional maps of an emissions plume in the atmosphere. Companies using this technology can get a deta...'Bat saliva' drug and new MRI techniques offer hope for acute stroke treatment
...(after the onset of stroke symptoms) of nine hours versus three. "The impact of these results cannot be overstated," says Rowley. "Buying more time to treat stroke symptoms-and the ability to safely restore blood flow to the brain-means we can give acute stroke victims hope for a better outcome, even if hav...Natural killer cellers are made, not born
Call it the immune system's version of nature versus nurture. For years, scientists regarded natural killer cells as a blunt instrument of the body's immune defense system. Born to kill, these cells were thought to travel straight from the bone marrow, where they are manufactured, to the blood, circula...Ancient DNA mutations permitted humans to adapt to colder climates, UCI researchers find
... our diet that are allocated to generate body heat versus work. According to Douglas C. Wallace, the Donald Bren Professor of Biological Sciences and Molecular Medicine at UCI and one of the co-authors of the report, after early humans migrated to colder climates, their chances of survival increased when ...