Scientists decipher genetic code of biothreat pathogen
...ological weapon, has an extremely regulated set of virulence genes and an unstable genome that may explain the ... horses, mules and donkeys. "The combination of virulence genes and genomic instability may explain why some scientists consider this to be the ultimate bacte...Missing genes may help explain why plague bacteria are so deadly
...c factors that contribute to the plague bacteria's virulence could aid researchers in developing better ways to... candidate for bioterrorism because of its extreme virulence and its potential to be spread through the air as well as by infected fleas. To get at the genetic b...UCSD biologists discover cell's defense mechanism against class of disease-causing bacterial toxins
...reacts to protect itself against a major bacterial virulence system," says Raffi V. Aroian, an associate profes...a very basic understanding of how a major class of virulence factors works. In addition we have now the tools to try to understand this in greater detail." Fund...Inadequate vaccines can help breed more vicious malaria strains
...The researchers then tested whether this increased virulence would be retained if parasites were transmitted by...other words, immunity accelerates the evolution of virulence in malaria, even after mosquito transmission, making them more dangerous to their non-immunised host...Common worm provides insights into salmonella virulence
...ing the worm, known as Caenorhabditis elegans. The virulence factors -- injected into the host cells by Salmone...eason of the remarkable overlap between Salmonella virulence factors required for pathogenesis in mammals and worms. For their experiments, the team used the C. ...American Society for Microbiology honors Timothy Yahr with 2004 Merck Irving S. Sigal Memorial Award
...ments governing its expression, and several of the virulence factors it secreted. As a result of this groundbre...ently been identified as a factor in P. aeruginosa virulence as well, so Yahr's assay is both innovative and timely. A graduate of the University of Wisc...Researchers describe long-perplexing 'magic spot' on bacteria
...od poisoning. This protein, called RfaH, regulates virulence a bacterium's ability to cause disease in pathogens such as Escherichia coli and Salmonella enterica, bacteria that cause food poisoning in humans. Artsimovitch and her colleagues identified previously overlooked RfaH genes in other bacterial patho...'Library on a Slide': Whole genome microarrays for comparative genomics
...hich genomes contained the hemolysin gene a known virulence factor. The results from the array experiment matc...cross species especially horizontally transferred virulence factors and antibiotic resistance genes."...Experiments establish 'protein-only' nature of prion infections
...n prions. This includes how strains can affect the virulence of a disease or how likely it is to jump a species."...Digging for truth in Guatemala
... for past atrocities lash out with ever increasing virulence at those who are collecting evidence and mounting bids to bring them to justice." FAFG Executive Director, Fredy Peccerelli will be present at the reception to accept the recognition on behalf of the Foundation. Peccerelli is a founding member of the...Gene mutation leads to super-virulent strain of TB
...chers disabled in the TB bacteria, as an important virulence factor that helped the organism invade cells. Rese...mption among scientists that disabling a potential virulence gene weakens a pathogen." Morici and Nobuyuki Shimono, assistant professor of medicine at Kyush...Enzyme revealed that is key to fungus's ability to breach immune system
...mune system -- led to a significant loss of fungal virulence in mice, the team found. That loss of virulence stemmed from the fungus's inability to launch a counterattack against components of the innate immun...JCI Table of Contents, 1 October, 2003
...fies App1 as a novel regulator of phagocytosis and virulence and may set novel criteria for antifungal drug dev...ication of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans AUTHOR CONTACT: Maurizio Del Poeta Medical University of South Carolina,...Salmonella uses molecular staples to change structure of infected cells
...ranging from plant pathogens to the plague share a virulence system that is quite similar to the one Salmonella...called "type III" or "contact dependent" to inject virulence factors directly into host cells. "Bacteria have a whole armament of very sophisticated virulence pr...Dual action anthrax vaccine more effective
...g against systemic anthrax because it targets both virulence factors of Bacillus anthracis--its toxin and its c...o anthrax molecules that are the bacterium's major virulence factors in disease, but in a vaccine act as antigens, stimulating an infected person's immune system...Unraveling the genetics of fusiform rust
...r resistance in the pine corresponds to a gene for virulence or avirulence in the fusiform rust pathogen. 'Tre...ecome infected by forms of the pathogen that carry virulence to these resistance genes. To more effectively manage for the disease, we need to not only identify ...Leading bacterial pathogen is sequenced
...g the plague bacterium Yesinia pestis -- inject virulence proteins into healthy host cells using what is called a "type III secretion system." The researchers discovered the genes encoding more than 35 injected-virulence proteins, more than for any other known pathogen, through collaboration with Cornell Th...An aspirin a day keeps Staphylococcus aureus away
...s. Aspirin has previously been shown to reduce the virulence of S. aureus in models of endocarditis. In an earl...nequivocal strategy to downregulate staphylococcal virulence using a cheap, simple, relatively non-toxic, resorbable compound such as SAL may be seen as major pr...JCI table of contents, July 15, 2003
...s. Aspirin has previously been shown to reduce the virulence of S. aureus in models of endocarditis. In an earl...nequivocal strategy to downregulate staphylococcal virulence using a cheap, simple, relatively non-toxic, resorbable compound such as SAL may be seen as major pr......cientists. In the first comprehensive study of the virulence of Listeria monocytogenes, researchers report that how well the bacteria attach to cells does not alone determine the degree of illness. The factors that determine if a person becomes ill and the degree of illness include the levels at which the path...