Tag: "virulent" at biology news

Worm brings death to coral

...oral bleaching. Crucially, it turns out to be more virulent at higher temperatures. "Coral biologists are not microbiologists," says Rosenberg. "They saw the association of bleaching with temperature, but they did not see the bacterium." The microbe, named Vibrio shiloi, was responsible for bleaching the sto...

Researchers identify new gene associated with breast cancer

...t of breast cancers, and is associated with a more virulent form of breast cancer. In breast cancer, the grade of the tumor refers to the degree of malignancy or differentiation of tumor tissue, e.g., well, moderately well, or poorly differentiated, and undifferentiated or anaplastic. Prognosis of patients w...

New proteomic techniques reveal workings of bacteria linked to cystic fibrosis

...P. aeruginosa become virulent. P. aeruginosa is so virulent that it will often kill cystic fibrosis patients. The highly sensitive quantitative proteomic analysis of a whole bacteria performed in this study implicates a cell signaling system, Pseudomonas quinolone signal, or PQS, that may help the bacteria ad...

Exotic Newcastle disease

...ntify a target sequence to distinguish the highly virulent forms of the virus from other forms. This has been extremely useful in the rapid differentiation of exotic Newcastle disease virus from closely related Newcastle disease viruses used in vaccines or those causing less severe disease. "To the best of...

Life sciences publishers take steps to address potential misuse of information by bioterrorists

...aces restriction on possession of the particularly virulent microorganisms and toxins known as select agents. The Biopreparedness Act requires registration for possession of select agents, security clearances for access, and security and reporting systems when working with these agents, Atlas said. The fear t...

Puzzle solved on how influenza builds its infectious seeds

... a better understanding of one of the world's most virulent diseases. This insight into the genetic workings t...ous particles for the influenza A strain, the most virulent and potentially dangerous flu virus. "What's unique about this virus is that its genome is fragmente...

JCI Table of Contents, January 2, 2003

...fective antibacterial strategy isphagocytosis, and virulent bacterial strains have evolved antiphagocyticstrategies. Searching for new virulence factors in group B streptococcus,Craig Rubens and colleagues isolated the cspA gene from a highly virulentstrain. As they report (pages 61-70), cspA encodes a novel ...

Food pathogen vector shows promise against cancer

...tudy, researchers infected mice with an especially virulent line of melanoma. Six of the eight mice whose immune system was primed with the E. coli/Listeria vector remained tumor free for more than 90 days post-tumor challenge, and the remaining two mice showed significant delay in tumor growth compared to ...

JGI to decode DNA of destructive plant pathogen

...a genomes, the scientists hope to uncover clues to virulent diseases that are attacking 17 species of trees on the West Coast, including redwoods, big leaf maples, bay trees and Douglas fir, and causing serious damage to soybean crops in the Midwest and South. "This is an ideal opportunity for genomics to mak...

Sequence provides insights into a pathogen's virulence mechanism allowing for vaccine development

...s emerged in recent years as a more widespread and virulent cause of illness in certain adults. "We were surpr...in why some strains of S. agalactiae are much more virulent than others." Tettelin and other TIGR scientists did the comparative genomics analysis in cooperatio...

Technique to induce cancer cells to 'commit suicide' developed by Hebrew University scientists

...ers is directed specifically against an especially virulent brain tumor cancer and is not harmful to normal cells. This represents a significant improvement over current chemotherapy treatments, which kill cancer cells but also have harmful effects on normal cells. In laboratory tests, the induced virus tech...

Researchers discover how herpes tricks the immune system

...nd that viruses lacking an RCA mimic were far less virulent than the normal virus: It took 100 times more of t...ing C3. In this case, the mutant virus was just as virulent as normal viruses in normal mice. Without C3 in the infected animal, the virus did not need to disgu...

Cause of hepatitis A virulence pinpointed

...ed two genes that give hepatitis A virus (HAV) its virulent properties. The team, led by Suzanne Emerson, Ph....its punch. They compared the genetic make-up of a virulent version of human HAV with that of an attenuated version of the same strain of virus by creating 14 a...

Sweet success on the way to vaccine for ulcers, stomach cancer, reported in Science

... help explain why H. pylori is such a tenacious, virulent bug, and provide new prospects for making a vaccine against it. There are many different strains of H. pylori , some more harmful than others. They cause virtually all ulcers (spicy food and stress do not) and have been linked to stomach cancer, one...

Collaborators receive $10.5 million to explore progression and treatment of prostate cancer

...genes and proteins that make prostate cancer cells virulent and stimulate their deadly march into human bone. The project grant is called Mechanisms and Markers of Prostate Cancer Metastases. "UW brings a strong track record to the table with its past research and we will also draw upon the strength of the...

Viruses help strep bacteria turn deadly

...l viruses are the culprits behind the emergence of virulent select new bacterial strains. Those viruses, call...nt and treat infections and to understand how new, virulent strains emerge," says Dr. Musser, who directs the human bacterial pathogenesis laboratory at NIAID's...

National Institutes of Health green lights additional research into new breast imaging system

...ding. Ironically, the cancers also tend to be more virulent and grow faster. A Clemson University physicist is working on a laser-imaging system enabling more accurate views of breast tissue. Given the go-ahead from the National Institutes of Health, Clemson physicist Huabei Jiang will lead the five-year $1....

A new weapon to disable bacteria discovered

...roteins to attack human cells. Shigella uses these virulent proteins to invade any cell in the body and then t...d Medical School. Interestingly, elastase destroys virulent proteins not only in Shigella, but also in Salmonella, the cause of typhoid fever and in Yersinia, t...

Single gene leap led to flea-borne transmission of plague bacterium

...n any of multiple ways, to emerge as novel or more virulent agents of human disease. In the new report, Dr. Hinnebusch and his colleagues from Sweden, Michigan, and NIAID describe how they explored the source of this gene and later identified the critical role it plays. The gene codes for an enzyme known as...

Researchers narrow search for structure of cholera toxins extracellular transport signal

...l help scientists understand how cholera toxin and virulent proteins of other pathogenic bacteria migrate through their cellular membranes to cause disease. Using chitinase, a protein known to be secreted by V. cholerae by the same mechanism as cholera toxin, the researchers engineered a series of insert...

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