Veterinarians discover first known case of canine distemper in a wild tiger
...ation," said Dr. Quigley. In 1994 canine distemper virus killed a third of the lions in the Serengeti. The source of that virus was domestic dogs living with local pastoral communities. In the Russian Far East, canine distemper ...Scientists discover proteins involved in spread of HIV-1 infection
...o spread infection to other cells. To do this, the virus hijacks a pathway that normally sorts proteins int... human tumor susceptibility gene 101 (TSG101). The virus then uses TSG101 to take control of the protein sorting and vesicle formation machinery and use it f...The future of HIV therapeutics is brightening, according to Gladstone Institutes Director
... life cycle, the entry of the HIV virion (a single virus particle) into host CD4 T-cells, are quickly movin...5, one of two key surface receptors needed for the virus to penetrate the cell. Although these HIV co-receptors were identified only seven years ago, basic s...Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
...l Care Products.) Measles: Compounds that inhibit virus could help close vaccination gap -- Measles remai...es, the non-peptidic compounds inhibit the measles virus and block the virus from entering cells. Although further testing is needed, the researchers hope th...Study of flu patients reveals virus outsmarting key drug
...s' heel that results in a drug-resistant influenza virus capable of infecting new human hosts, according to...ound is that a single (genetic) mutation makes the virus resistant," says Kawaoka, an authority on influenza who holds an appointment at the UW-Madison Schoo......susceptible to a second infection with another HIV virus including viruses resistant to drugs. This infection with a second HIV virus is called superinfection. "This is the first time we have seen a patient infected with two differe...Images reveal how rotavirus - leading cause of diarrhea - enters cells
...e the immune system, without having to use a whole virus to make a vaccine. The researchers are now collab...imes severe enough to require hospitalization. The virus kills about 440,000 children each year, mainly in developing countries. The only licensed vaccine, ...Bright idea could doom cancer and viruses, say Purdue scientists
...ed to light, can kill tumor cells and deactivate a virus closely related to the West Nile and yellow fever ...e rhodium complex capable of rendering the Sindbis virus inert," Morrison said. "Since blood cells and platelets do not themselves have nucleic acid, they ar...No longer just for biology, RNA can now be built into 3-D arrays
... In 1987, Guo discovered that a bacteria-infecting virus possesses a biomolecular nanomotor that requires RNA molecules to function. While determining how RNA works in that motor, he learned to manipulate and control RNA assembly. Now, Guo and his colleagues have applied that knowledge to building artifi...First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
...st human parainfluenza virus-type 1 (hPIV-1). This virus is the most common cause of croup, a pediatric res...s inside the body. The vaccine consists of Sendai virus (SeV), a mouse virus that is similar enough to hPIV-1 to act as a vaccine, but different enough to h...Disease-resistant papaya saves Hawaiian papaya industry
...w papaya, genetically resistant to papaya ringspot virus (PRSV), has rescued the Hawaiian papaya industry a...ly spreads when aphids (small insects) pick up the virus on their mouths while feeding on infected plants and continue to feed on healthy plants. In the lat...Virus known for its photo ops makes its movie screen debut
...T LAFAYETTE, Ind. - High-resolution snapshots of a virus attacking its host - which have culminated in a mo...llow scientists to alter the baseplate so that the virus could infect cells other than E. coli. T4 might then be used to deliver beneficial genes to damaged ...Nucleic acid-amplification testing further safeguards nation's blood supply
...oximately five HIV-1 infections and 56 hepatitis C virus (HCV) infections each year since it began being us...on of antigens requires time for a higher level of virus to appear in the bloodstream. With the use of NAT for HCV, the window period is reduced by approxi...New model can aid in understanding immune system diseases
...tudy. Such is the case with Epstein-Barr, a common virus that is often harmless but likely contributes to m...rtant transforming protein that is involved in the virus in humans," said Bishop, who also is associate director for basic science research at the Holden Com...New mechanism for display of foreign proteins to immune system
...used to alert the immune system to the presence of virus infected cells and abnormal cells like cancer cells. The findings provide new insight into how the immune system identifies potentially harmful cells and may be exploited for future development of more effective vaccines. It is well established that ...X marks the spot: Vector insertion is viral specific
...mpared vectors derived from human immunodeficiency virus (HIV), murine leukemia virus (MLV), and avian sarcoma-leukosis virus (ASLV). They found that HIV integrated near active genes; ML...Retroviral gene therapy? ASLV, HIV, and MLV show distinct target site preferences
...ed vectors derived from the human immunodeficiency virus (HIV), avian sarcoma-leukosis virus (ASLV), and murine leukemia virus (MLV). Introducing the viral vectors into human cells, the authors...Protective gene may enhance vaccine responses
...els produced a severely diminished response to the virus when exposed to it a second time. On the other h...mal number of memory T cells. When faced with the virus a second time, these memory T cells produced an overwhelming response, completely eradicating the in...Jefferson Lab detector technology aids development of cystic fibrosis therapy
...has no known cure. In conventional gene therapy, a virus is used to deliver a therapeutic gene to the targe...lung infections and inflammation. "If we deliver a virus to the lungs, even if it's a hollow virus, it will initiate an inflammatory response, making the pat......ole in a microscopic "motor" used by the bacterial virus phi29 (see related story), Guo has continued to study the structure of this RNA molecule for years. It formed the "pistons" of a tiny motor his lab created several years ago, and members of the team collaborated previously to build dimers and trimers...