Researchers make promiscuous animals monogamous by manipulating genes
... ventral pallidum. The scientists used a harmless virus to transfer the vasopressin receptor gene from prairie voles into the ventral pallidum of meadow voles, which increased vasopressin receptors in the meadow vole to prairie-like levels. The researchers discovered, just like prairie voles, the formerly...Carnegie Mellon computational biologist Russell Schwartz receives prestigious CAREER award
...could identify promising drugs that interfere with virus assembly before they begin testing the drugs in the laboratory. This process could accelerate the discovery of drugs tailored to specific targets so that they would be selective only for certain problems and unlikely to cause system-wide side effects...LARGE protein can overcome defects in some types of muscular dystrophy
...of LARGE in the mice, the researchers engineered a virus expressing the LARGE gene. When they injected the virus directly into the muscle of mice that were a few days old, the muscle cells produced functional LARG...Susceptibility of mice to mousepox offers promise of smallpox protection
...s into the immune response of mice to the mousepox virus could enable scientists to combine antivirals and ...ses such as smallpox, monkeypox, and vaccinia, the virus used to vaccinate against smallpox, all make proteins that bind to IFN- to interfere with its signal...Yale professor receives Johnson & Johnson Focused Giving award
... and has been used in the past to target essential virus genes and decrease infection. Understanding how to affect the expression of multiple genes in a coordinated manner has important implications for many basic biological functions, and disease treatments. ...Tiny tango: Device sorts microscopic particles with speed and precision
.... Another use may be in distinguishing one type of virus from another, because many viruses have a unique s... let us say in an instant that we have one kind of virus and not another." In pharmaceuticals, the size of the drug particles in a capsule can play ...Late invasion of infected cells into the brain causes HIV dementia say Temple researchers
...te in the disease, there's a resurgence of the HIV virus from the macrophages." Rappaport and his collaborators believe that this longstanding theory does not hold true, that the early invasion of HIV-infected macrophages are controlled and cleared away by the body's immune system. "Late during AIDS...Temple virologist receives NIH grant to continue investigation of HIV dementia complex
...early during infection, secretly carrying the AIDS virus and allowing the long-term resident macrophages of...u put an HIV patient on drugs or drug therapy, the virus goes way down to often undetectable levels," notes Rappaport. "But when you take them off the drugs...Study suggests double punch could more efficiently kill viruses
... For example, the chickenpox vaccine contains dead virus that, when administered, trains the body to recogn...However, some viruses, like human immunodeficiency virus (HIV) and smallpox, travel inside cells where antibodies cannot penetrate. These viruses are transfe...Nanoparticles illuminate brain tumors for days under MRI
...hown that an iron oxide nanoparticle as small as a virus can outline not only brain tumors under magnetic r...ach iron oxide nanoparticle is the size of a small virus and is much smaller than a bacterium but much larger than an atom or standard gadolinium contrast mo...The search for a safer smallpox vaccine: New data released on promising candidate
...hat the vaccine, given to mice, protects against a virus related to smallpox that has been aerosolized. Acc...accine is produced in a cell culture from vaccinia virus that has been attenuated, or modified, so that it can initiate an immune response without causing se...Friendly bacteria block HIV infection
...cur naturally in the human mouth can snare the HIV virus and even cells it has infected, according to resea...the sugar coating on the envelope that encases the virus particle and blocked infection. The bacteria also bound the sugar coating on immune cells, causing ...Can we restore wetlands and leave the mosquitoes out?
...resent in the Tucson area now, Arizona's West Nile virus season has already begun. "Several obstacles block people from frankly discussing mosquito problems," writes Willott in her paper "Restoring Nature, Without Mosquitoes?" The article will be published in the June issue of Restoration Ecology. The shor...Mite transmits viruses damaging to wheat
...bors of conservation reserve program land. Neither virus can travel without the help of a carrier. Research...he viruses, he said. Plants infected by either virus will show similar symptoms with subtle differences, Rush said. High Plains virus causes a yellowing ...NIH awards $20.7 million to make smallpox vaccine safer
...72. Although the only known stocks of the smallpox virus are contained in laboratories in the United States...and health officials fear that others may have the virus and use it as a terrorist weapon. As a result, military and healthcare professionals have begun rece...HIV takes cellular opportunities to aid infection
Scientists will have a new view of how the AIDS virus (HIV) enters a target cell and begins its process ...ey enter a cell. The study was done with a chicken virus that was modified to contain the genes of HIV. Both the chicken virus and HIV are retroviruses, whic...A new way to kill cancer: SLU research shows viruses can destroy lung, colon tumors
ST. LOUIS - A genetically engineered virus can selectively kill cancerous cells in the lung a...gene therapy vectors," changing these genes so the virus will attack cancer cells. "Some of our vectors are designed to destroy many different types of cance...Tips from the Journals of the American Society for Microbiology
... in Vietnam. Researchers then tested for the SARS virus using a new one-step method, Loop-Mediated Isother... 87 to 100 percent effective in detecting the SARS virus in the samples collected. "The one-step single-tube accelerated real-time quantitative RT-LAMP...Plant disease under the homeland security microscope
... streak mosaic virus, and rhizomania, a soil-borne virus affecting sugar beets.Federal and state agencies monitor national borders for plant pest introductions. Still, on occasion, new ones will slip through. Growers often spot these anomalies, Stein explained. Professionals at land-grant universities hand...Muscle-derived cells and gene therapy may cure for post-prostatectomy erectile dysfunction
...an Kim, Ph.D., researchers injected herpes simplex virus vectors that deliver glial cell derived neurotrophic factors (GDNF) factors that facilitate the recovery of injured nerves into the corpus cavernosum or cavernous nerve of rats at the time of cryo-injury to the nerve. The cavernous nerve is the ner...