Genomic changes reveal evolution of SARS virus
...tudy of changes in the genetic make-up of the SARS virus through the recent epidemic has allowed researcher...rs of human-to-human transmission, reveals how the virus quickly adapted to its human hosts. The third phase involved selection and stabilization, as the vi...Smallpox in 50-year-old tissues detected by integrated diagnostics approach
...s concern that undisclosed reference stocks of the virus may exist--and given its potential as a biological threat agent, improved methods of detection and identification are a high priority. According to an article published in this month's issue of Laboratory Investigation , the specimen used in the stu...Mount Sinai School of Medicine conducting clinical trials with gene therapy for colorectal cancer
...began recently. Dr. Woo and colleagues developed a virus that can carry the IL12 gene into the cancer cells. "The virus is developed in a special multi-million dollar facility here at Mount Sinai," said Dr. Woo. "This st......disease from poultry, but the big fear is that the virus could turn into a form capable of spreading from p...stly children. So far there is no sign of the bird virus spreading between people. But if someone is infected by H5N1 and a normal human flu virus at the sam...Ebola outbreaks are simultaneous 'mini-epidemics'
...and wildlife, recent flare-ups of the deadly Ebola virus in Central Africa are actually multiple epidemics ... said that scientists previously believed that the virus forms in epicenters and quickly spreads by animals moving through the forest. Eventually people cat...Researchers develop model to help control West Nile outbreak
...loped the first model to predict risk of West Nile virus in North America--a tool that could help prevent t... Mark Lewis are co-authors on the paper. West Nile virus is an emerging infectious disease in North America that spreads primarily through contact between bi...RNA lariat may tie up loose ends to decades-old mystery of retrovirus life cycle
...retroviruses, including the human immunodeficiency virus (HIV). Knowing the details of thisstep in the infe... HIV-2, and forms of the human T-celllymphotrophic virus (HTLV). Other retroviruses are known to cause cancer in animals. "The new results provide remarkab...A viral cure for type 1 diabetes
...t that infection with lymphocytic choriomeningitis virus (LCMV) during the prediabetic period completely abolished the diabetic process in two distinct mouse models. This protection against the development of type 1 diabetes correlated with a reduced number of autoaggressive CD8 T cells in pancreatic isle...JCI table of contents, January 2, 2004
...t that infection with lymphocytic choriomeningitis virus (LCMV) during the prediabetic period completely ab...ufacture virus, and host cell lysis to release new virus particles. These viruses then mature to a latent state, where infected host cells survive and the vi...Results of pivotal study for GlaxoSmithKline's Valtrex published in New England Journal of Medicine
...REX reduced the risk of overall acquisition of the virus (with or without symptoms confirmed by a lab test)...5, or 45 million, Americans were infected with the virus that causes genital herpes. Experts estimate that up to 60 million Americans have the virus that ca...Solving the Ebola enigma: satellites will provide clues
...ternal bleeding in humans and also apes. The Ebola virus undoubtedly has its home in deep tropical jungle, ...whatever organism actually serves as the long-term virus host by testing the blood of captured jungle animals. The sheer biological diversity and geographic...Science's breakthrough of the year: Illumination of the dark, expanding universe
...ict isolation of patients, eventually cornered the virus after more than 8,400 reported cases and more than 916 deaths. Science's Breakdown of the Year emerged on 1 February 2003, when the space shuttle Columbia disintegrated as it re-entered the atmosphere after a science mission. ...The common cold as cancer fighter? SLU prof's lifetime work moving into clinical trials
...u've figured out a way to genetically engineer the virus so that it fights and kills cancerous cells - whil...gene therapy vectors," changing these genes so the virus will attack cancer cells. "Some of our vectors are designed to destroy many different types of cance......essed high T-cell counts with detectable levels of virus in the blood. The researchers put each man through...une systems of introverted subjects replicated the virus between 10 to 100 times as fast as in other patients. Release URL, if available: The URL must poi...Purdue biologists expose the inner workings of viral machine
... Purdue University scientists have peered inside a virus and visualized for the first time how it produces ...re shows not only the molecular composition of the virus but even the position and orientation of those molecules. "We have visualized the innards of a human...SARS coronavirus part bird, part mammal: study
...n hosts. This, they believe, forms an entirely new virus unrecognizable to human immune systems. Understand...he specific evolutionary changes that enables this virus to spread into the human population should dramatically improve our understanding of why this partic...Early promise for treatment of Ebola
...adly Ebola virus. Haemorragic fever from the Ebola virus is fatal in up to 80%of cases in humans. The virus is thought to cause excessive blood coagulation and thrombosis leading to organ dysfunction. Inhibit...Drug shows promise for Ebola virus treatment in primates
...e symptoms triggered by the virus, rather than the virus itself. Ebola causes coagulopathy, or abnormal blood clotting, which ultimately leads to massive hemorrhage and death. Studies at USAMRIID suggest that macrophages, a type of white blood cell, play an important role in this process. When a host i...Ebola virus-like particles prevent lethal Ebola virus infection
...sts have successfully immunized mice against Ebola virus using hollow virus-like particles, or VLPs, which ...s (USAMRIID) describe creating VLPs from two Ebola virus proteins, glycoprotein (GP) and matrix protein (VP40). These VLPs resemble a shell of infectious vi...Breakthroughs lead to better understanding in prevention of transfusion-transmitted infection
...ols with nucleic acid testing for HIV, hepatitis C virus (HCV) and WNV, but there is now a movement toward ...AT yield for HIV-1 (1:3.7 million) and hepatitis C virus (HCV, 1:266,000) results in prevention of approximately three HIV-1 and 50 HCV viremic seronegative ...