Tag: "visualizing" at biology news

The CIA Would Like To Know What Scientists Are Seeing Over The Rainbow

...ncers. Higher-resolution molecular techniques for visualizing chromosome regions, particularly fluorescence in situ hybridization, or FISH, later improved the process. FISH uses DNA probes labeled with fluorescent dyes to identify specific chromosomal regions. Spectral karyotyping is a new way to interpret dat...

Molecular Control Mechanism Of Embryonic Development Unraveled

...e been implicated in some childhood leukemias. By visualizing howPbx1 interacts with a Hox protein and with DNA, Wolberger and colleagues have determinedthe precise way in which the proteins interact with one another to control development. Pbx1, by interacting with Hox proteins, is able to control theexpressio...

'Altered state' may be responsible for creating important brain chemicals

Twenty years after visualizing a surprising left-handed form of the DNAdouble hel...ons." Adds Rich, "Twenty years after first visualizing a left-handed form ofthe DNA double helix, it may now be possible to see ways in which nature usesth...

Computers have had dramatic impact on chemistry

...e an importantresource. * We are getting better at visualizing scientific information. We can createholographic images of molecules and even interact with them physically to feelthe strength of the bond between a pharmaceutical agent and the receptor, forinstance, if we try to pull them apart. * There is experi...

Snapshot of new drug marks a major advance by Memorial Sloan-Kettering researchers

...o anenzyme and affects how it regulates cells. By visualizing how the drug, calledSAHA, nestles into the active site of the enzyme and subtly alters itsstructure, the picture will enable investigators to make more potent and morespecifically targeted versions of these drugs. The first clinical trial of SAHAis ...

Jellyfish protein illuminates active immune cells

...em, Schaefer turnedhis attention to the problem of visualizing MEKK2 in active, living T cells. Thetwo researchers, with help from others in the Johnson laboratory, developed asystem to record digital movies of MEKK2 fused to GFP under conditions that didnot disturb the activity of the helper T cells. The resul...

Brookhaven Lab collaboration determines the atomic structure of a key enzyme called a 'biological blowtorch'

...ting is that they have produced a molecular movie, visualizing five critical steps in one of the enzyme's typical chemical reactions. The researchers used an intense x-ray beam from one of the facilities, or "beam lines" of Brookhaven's National Synchrotron Light Source (NSLS) to perform the study. In the reac...

Gorillas in the bits: remote sensing boosts efforts to protect mountain gorillas & rebuild Rwanda's economy

...- developed system offers a powerful tool for visualizing the potential impacts of change, Faust adds. Though the Dian Fossey Gorilla Fund International focuses on conservation of the gorillas, the well-being of the animals cannot be separated from the well-being of the country in which they ...

Simple and inexpensive, an artificial nose senses smell by seeing colors

...that is simple, fast and inexpensive and works by visualizing odors. Called "smell-seeing" by its inventors, the technique is based on color changes that occur in an array of vapor-sensitive dyes known as metalloporphyrins doughnut-shaped molecules that bind metal atoms. Metalloporphyrins are closely relate...

For the first time, scientists uncover how breast cancer metastasizes

...untilrecently there has been no effective means of visualizing lymphatic vessels.Using a new method for imaging lymphatic vessels, he and Skobe observed networksof lymphatic vessels deep inside breast tumor masses grown in mice. Upon closerinspection, the vessels appeared to be carrying tumor cells. Most striki...

New technology expands 'molecular photography' options

...ss Spectrometry," offers scientists a new tool for visualizing where proteins are located in cells and tissues. This kind of information is important to understanding how proteins work and how they change in disease states. The Vanderbilt team applied the new technology, described in the April issue of Nature ...

Visualizing protein synthesis in living neurons

... proteins. Schuman and her colleaguesbelieved that visualizing local protein synthesis in living neurons wouldprovide a more compelling picture than was currently available. The scientists began their efforts to create aprotein synthesis reporter by flanking the gene for a green fluorescent proteinwith two segme...

Cal-(IT)2 adds new industrial partner SGI

... believe our goal of developing a control room for visualizing environmental data in southern California from a real-time network of sensors will be met through the assistance and interest shown by SGI, and we intend to build the current installation significantly over the next 3-4 years. We believe this has nev...

Pictures reveal how nerve cells form connections to store short- and long-term memories in brain

...to study synaptic connections. One was a method of visualizing the rods and filaments of actin-the girders that make up the cytoskeleton, the internal skeleton of the cell. Using molecular biology techniques, fluorescent versions of actin were constructed and visualized as the neurons grew and changed shape to e...

Science's Top Ten: nanoscale computing circuits named top scientific advance of 2001

...ses, optical clocks and fundamental constants, and visualizing complex molecules and biological interactions. The editors also check in on the 2000 scorecard to see how well they did with last year's predictions. As the world's leading peer-reviewed general science journal, Science is uniquely suited to compil...

Another transmembrane protein structure solved by Rockefeller scientists

...of the Rockefeller scientists remarkable knack for visualizing the specialized proteins that provide ports of cellular entry for potassium, sodium, calcium and chloride. MacKinnon, who is a Howard Hughes Medical Institute investigator, leads a scientific team that is adding unprecedented detail to existing descr...

RIT collaborates with IBM on genomic research

... a database of microbial genomic data tools for visualizing the results of genomic comparisons, and protein structures from related and unrelated organisms. a unique, Internet resource for comparative genomic analyses offering otherwise unavailable computational abilities to academic and industrial researche...

Carnegie Mellon University receives NASA award to develop probes to detect life on Mars

...oth of detecting low levels of micro-organisms and visualizing high levels incorporated as biofilms or colonies," adds Fisher. Additionally, notes Lauren Ernst, project chemist, Martian life forms may contain different structural components than those found on earth. "We want our reagents to visualize any form ...

3-D imaging inside living organism, using quantum dots

...iological research context, for tracking cells and visualizing tissue structures deep inside living animals." Zipfel cited the study of vascular changes in cancer tumors as one possible application, cautioning that the Cornell researchers are not ready to recommend human-medicine clinical applications for quantu...

Breast fluid a better option for detecting cancer

...n methods rely on feeling a lump in a self-exam or visualizing a lump in a mammogram. By the time a lump has formed, the cancer has progressed. My technique, combined with Battelle's protein analysis capabilities, makes our approach one of the leading methods for identifying biomarkers for breast cancer in the...

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