Bacterial Toxin Surprises Scientists
... and, perhaps most devastating, loss of the vital electrical potential stored in the membrane. The researchers determined the parts of the protein that lie on each side of the membrane when colicin Ia is in its innocuous, closed-channel state and when it is in its har...Humble Pocket Gophers Shed Light On The Genetic Fortitude Of Cheetahs
...tors, such as habitat loss and predation, are more vital to cheetahs' survival than genetic diversity. No one has found a direct link, they say, between genetic shortcomings and the decline of cheetahs or, for that matter, any other species. The UCSC study does not address these latter concerns. It does, h...Researchers Find Possible New Route to Making Cancer Cells Vulnerable
...rugs primarily halt the cellular pump by removinga vital part, like a valve from a car's fuel pump. "Cyclosporin-related drugs are now being tested for their ability toreverse chemotherapy resistance in cancer patients, but little had beenknown about how these common immune suppressants work in this setti...Surprising Protein Movement Seen In Cells
Biologists have discovered that certain proteins vital to lifeand long thought to be immobilized within t...ion,the organelles would not function properly and vital lifeprocesses would break down. Scientists had proposed that the proteins are anchored andimmobilize...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
...oof before this." Both oxygen and NO are vital to life processes, but too much of eithercan damage cells. To keep the amount of oxygen and NO in balance, cellshave built-in systems to eliminate the excess. One way to do that is tohave transcription factor sensors that get turned on when too much ...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
...oof before this." Both oxygen and NO are vital to life processes, but too much of eithercan damage cells. To keep the amount of oxygen and NO in balance, cellshave built-in systems to eliminate the excess. One way to do that is tohave transcription factor sensors that get turned on when too much ...Major Plant Genome Research Project Underway
...nts and plant-based products. "Because plants are vital to our existence, increased understanding of the biology of plants will impact every facet of our lives, from agriculture, to energy, to the environment, to health," says Clutter. In 1990, the Multinational Coordinated Arabidopsis thaliana ...Duke's Russian Laser Making Ultraviolet Light And Gamma Rays
...action is critically important for predicting such vital details as therelative abundance of various elements in the universe. Measuring its details,however, is very difficult in the laboratory, Tornow added. A promising alternative is to study the reaction backwards by bombardingoxygen-16 with gamma rays...Pinpoint Gene Control Holds Promise For Nervous System Studies
...or life.But this can't be done with genes that are vital fordevelopment, such as NGF: Knocking them out in an animal that isstill developing usually kills the organism. "In our system, the animal develops as it normally would,"says Brooks. "Then we alter it later and study the molecular andbehavioral ...Proteins Interacting With RNA And DNA Are Surprisingly Similar
...ssential in the manufacture ofproteins rangingfrom vital enzymes and hormones to hemoglobin and structuralcomponents. DNA,or deoxyribonucleic acid, contains the huge library of geneticinformationorganisms need to reproduce and to make RNA. Both RNA and DNA aremade ofmolecules called nucleotides. But RNA is...High Levels of Vitamin C Prove Toxic to HIV
...(dehydroascorbic acid). Once inside the cell, this vital nutrient is reconverted to its original form, whose different shape and size prevent it from leaving the cell. This series of studies prompted Dr. Golde and his colleagues to ask whether HIV-infected cells also take in higher-than-normal levels of g......o the report, continued federal support for R&D is vital to the continued strength of the research capabilities at these universities. Massachusetts receives the most federal R&D funds among the six states, with a $3.3 billion dollar inflow to the state economy in FY 1994, placing it sixth in the ...Emory Researchers Advance Gene Therapy Studies For Metastatic Melanoma Treatment
...ncer Center are uncovering new information about a vital cellular ingredient which they believe may direct the body's immune system to kill malignant melanoma tumor cells, the most dangerous, and potentially deadly, type of skin cancer. If large doses of this ingredient can be delivered to melanoma tumo...Duke Study Shows Early Marrow Transplant Key To 'Bubble Boy' Disease Cure
...or's marrow cannot rise upand attack the patient's vital organs -- a common complication with bonemarrow transplants. And, by removing these cells before the transplant, the infant avoidsthe toxic drugs normally given to suppress the donor's T-cells. Results from the study of 79 SCID patients ...First Planned Release Of Captive Lemurs In Madagascar Wilds Expected In Fall
...nts will be remindedthat the Betampona refuge is a vital repository for clean drinking waterand also protects their villages from flooding. Madagascar is one of the world's poorest nations, and a major priorityfor conservationists. Its once-rich array of wildlife has been decimatedby habitat destruction, ...New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops
...ds. That meant her pottery studies could give him vital clues about how domesticatedcorn looked many centuries before the Spanish conquest. So her research trips to Mexico and Peru aided Mangelsdorf's continuingwork. In turn, Mangelsdorf's passion quickly rubbed off on her. Eubanksbegan studying biology ...Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos
...and showed that it makes a protein that plays a vital role in controlling cell cycle in all human and mammalian cells. When pRb-2/p130 is altered and cannot produce its protein, the cell may not reach its natural stage of programmed cell death. Instead, the cell continues to live and grow ...Low Oxygen, Key To Fetal Development, Also Offers Cancer Clues
...early pregnancy, controlling thedevelopment of the vital bridge between mother and baby. The finding also sheds light on cancer, says co-author JohnLudlow, associate professor at the University of Rochester CancerCenter, since hypoxia, or low oxygen level, also plays a role incancerous growth -- a pro...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
...ous throughout the body’s tissues and play vital roles in cell growth control. The p107 protein is found in high levels in breast and prostate tissue. The pRb-2 protein is present in high amounts in normal lung cells. Yet when Rb-2/p130 is altered and cannot produce pRb-2 , the c...Captive Lemurs To Depart For Madagascar Oct. 17 For First Release Into The Wild
...be reminded that the Betampona refugeconstitutes a vital repository for clean drinking water and plentiful water for their rice fields, and also protects theirvillages from flooding," he said. Madagascar is one of the world's poorest nations and a major priority for conservationists. Its once-rich array o...