Tag: "way" at biology news

Streptococcus infects humans by thwarting blood clotting

... microbes. The research is also likely to open the way to new understanding of the factors that enable ba...ng infection by that bacterium, but in opening the way to similar studies of other bacteria. In infecting its human host, the group A streptococcus secrete...

Strep disrupts blood clotting to infect humans

... infection by this bacterium, but also opening the way to similar studies of other bacteria that afflict humans. "Understanding why bacteria in general are so species-specific has been a major problem for a long time," Ginsburg said. "And this species-specificity had greatly hindered our ability to dev...

Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies

...hers have shown that when cells engineered in this way are placed in a specific region of the heart, they form linkages permitting direct communication with the heart muscle cells. The engineered cells emit a signal, carried by an ionic current that stimulates the hearts of experimental animals to genera...

Review article makes case for a new source of cells in the body

...ts," Dr. Sohal says. "VENT cells would be a simple way of providing stem cells to various tissues because nerves connect to every tissue and you would not be dependent on every muscle, every nerve, every bone to make sure you keep a small reserve," Dr. Sohal says. The work to date has been in chicken, qu...

University of Pittsburgh receives $10 million grant for head and neck cancer

...fects of most therapies," said Dr. Siegfried. "One way to address this difficulty is to develop therapeutic approaches that target multiple signaling pathways." Drs. Siegfried and Grandis are examining the interaction of two types of protein receptors implicated in the proliferation of head and neck canc...

What actually influences air pollution over the Indian Ocean?

...umes of nitrogen oxide pollution extending all the way across the central Indian Ocean, mainly in the middle troposphere, originating from Africa in the west and from southeast Asia (Indonesia and other countries) in the east (Fig. 1b). "Our results suggest that the central Indian Ocean is not always as ...

UC Irvine scientists to develop vaccine to combat bioterrorism threat from deadly bacteria

... is a national and worldwide goal, and is the best way to blunt a bioterrorist threat," said Philip Felgner, principal investigator of the research project and director of the proteomics laboratory within the Center for Virus Research . "Even if we have antibiotics, it will be difficult to treat everyon...

Images reveal how rotavirus - leading cause of diarrhea - enters cells

...st infection. "The work is a clear example of the way in which structural studies can contribute to new good ideas about strategies for vaccines," says Senior Investigator Stephen Harrison, Ph.D., a Howard Hughes Medical Institute investigator and chief of CHB's Laboratory of Molecular Medicine. Vacci...

UCSD biologists develop 'super-endurance' strain of mice

...gy at UCSD, who headed the study. "By changing the way skeletal muscles respond to low-oxygen levels, we've developed muscles that appear to be superiorly adapted or trained for long bouts of submaximal aerobic exercise. But these muscles also become damaged more easily than normal muscles during exercis...

Synthesized molecules studied as weapon to stop cell division in cancer cells

...k. This a simple change -- the swing of an arm one way or another to open or close the U results in a large conformation change in a protein. The researchers synthesized cis and trans shaped inhibitors and introduced them into cancer cells. These inhibitors mimic part of the Cdc25 protein but do not be...

Length of sex act in flies dictated by genetics

...and "timeless" regulate mating behavior in a novel way unrelated to the clock. These genes control not only when certain behavioral acts may occur, but also how long they may last. Clock genes are also found in humans they have been conserved between tiny fruit flies and humans through millions of years...

Carnegie Mellon scientists reveal ways of studying, resolving PCB contamination in US rivers

...force, Carnegie Mellon scientists have developed a way to identify true shifts in specific PCB congener distributions over time in river sediments by tracking pairs of PCB congeners whose ratios do not vary from Aroclor lot to Aroclor lot. This computationally intensive procedure, which was tested using ...

Anticancer drug zebularine specifically targets tumor cells

...uch of the difference, Jones notes, comes from the way zebularine is preferentially taken up by the cance..."And we have since shown that it can work the same way in mammalian cells." In a previous study published in the Journal of the National Cancer Institute i...

Why your knees and quads hurt more after running than walking: You're only human

...e ground, and here, too, the knee extensors sprung way past the hip and ankle. Whereas all three joints increased the active muscle volume as speed increased and gait changed, the knee extensors increased 4.9-fold during running (to 49% of the three extensor groups combined, vs. 23% at a walk). This comp...

Genetically-engineered 'marathon mouse' keeps on running

... by pharmaceutical companies could be abused as a way to enhance athletic performance. Led by Howard Hu...n of the genetically altered mouse, the only known way to increase endurance was through physical training. "We thought that the enhanced PPAR-delta would...

In gene regulation, small is beautiful

...s designed small molecules that mimic in a general way the features of natural transcriptional activators. In this research, published online in the Journal of the American Chemical Society earlier this month, small molecule artificial activation domains developed in Mapp's lab were as effective as a nat...

New compound could give some types of cancer the one-two punch

...that successful; somehow cancer cells still find a way to form blood vessels." Li and his colleagues are continuing to look for even more potent analogs based on the structure of SU-5416. "We're developing small, easy-to-make compounds that are similar to established drugs, but hopefully much easier to c...

Clemson University spin-off uses corn to make plastics, provide cleaner air

...nnis Smith and his research group have found a new way to replace up to 50 percent of the chemicals that make regular plastics with polylactic acid. The end product is a plastic that has both the environmental friendliness of the corn-based product and the durability of regular plastics. Potentially, thi...

Scientists reinvent DNA as template to produce organic molecules

...ipping up of complementary DNA strands is a simple way to bring molecules at low concentrations together without having to develop an entirely new class of enzymes for each different type of molecule." The 10-base DNA strands used by Liu's team are large enough to be stable at room temperature and in the...

Researchers show how to assemble building blocks for nanotechnology

...iversity of Michigan researchers have discovered a way to self-assemble nanoparticles into wires, sheets, shells and other unusual structures using sticky patches that make the particles group themselves together in programmed ways. This method could be used to fabricate new materials and devices for nan...

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(Date:4/17/2014)... chronic inflammation in benign prostate tissue was associated ... association was found even in those with low ... published in Cancer Epidemiology, Biomarkers & Prevention ... Cancer Research. , An analysis of prostate tissue ... arm of the Prostate Cancer Prevention Trial (PCPT) ...
(Date:4/17/2014)... today in PLOS Pathogens , children who live ... can mount an immune response to infection with malaria ... of high fever and illness and partially control the ... may help researchers develop future interventions that prevent or ... Each year, approximately 200 million cases of malaria occur ...
(Date:4/17/2014)... Children,s Hospital Pediatrician-in-Chief Jon McCullers, MD, was recently ... issue of Nature Reviews Microbiology , one ... McCullers, a world-renowned infectious disease specialist, and chair ... of Tennessee Health Science Center, analyzed the epidemiology ... and 1968 pandemics, as well as more recent ...
(Date:4/17/2014)... NY (April 16, 2014) The cause of neuronal ... new study proposes that neurons may be mistaken for ... system, similar to the way autoimmune diseases like type ... body,s cells. The study was published April 16, 2014, ... new, and likely controversial, idea in Parkinson,s disease; but ...
(Date:4/17/2014)... Calif.) An international team led by researchers at ... complex, which plays a key role in cell division, ... This is the first time the complex has been ... make cyclin B1/Cdk1 an excellent target to control cellular ... The research was published online today in the journal ...
Breaking Medicine News(10 mins):Health News:Chronic inflammation may be linked to aggressive prostate cancer 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 3Health News:Study sheds light on how the immune system protects children from malaria 2Health News:Is Parkinson's an autoimmune disease? 2Health News:Dual role: Key cell division proteins also power up mitochondria 2
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