Structure solved by Scripps scientists shows one way that body controls gene expression
...ent RNA sequence motifs. Insights into the workings of the regulatory protein TIS11d are particularly valuable because these proteins are involved in a number of fundamental biological processes, such as inflammation, and are potential targets for therapeutics in diseases where these processes go awry...RNA inner workings partly unveiled in Stanford study
...n their findings and continue to explore the inner workings of RNA polymerase. "Because we have overcome technical problems in making the complexes, it opens a huge opportunity for a lot of other variations of this. We can do a lot of experiments that we couldn't do before," said Westover....Mind Science Foundation announces Rare Consciousness Research Awards
...xecutive Director, Joseph Dial. "Insights into the workings of our minds inform the ways in which we teach our children, make economic decisions, create art, develop computers, deliver healthcare, and implement justice." Dr. Emilio Romero, M.D., Chair of the Mind Science Foundation's Scientific Advisory Comm...Until now, scientists studying the workings of ultra-microscopic forms have had to rely on the scientific equivalents of still photos, something like trying to fathom driving by looking at a photograph of a car. Now, Prof. Irit Sagi and her team of the Structural Biology Department are using n...Purdue biologists expose the inner workings of viral machine
... have a much clearer understanding of the internal workings of the reovirus machine now - understanding that could play a role in determining how to stop those presses someday." The discovery was possible because of an innovative improvement on the microscope technology developed in Baker's lab at Purdue. To ...Researchers describe new technique for cataloging RNA targets in rare brain disease
...is capacity is believed to critical to the complex workings of human cells such as those found in the neurons of the brain. Nova was the first RNA binding protein discovered to regulate alternative splicing specifically in the brain. "The finding that Nova regulates RNA splicing in neurons was satisfying as ...Conference to highlight medical advances resulting from 50 years of DNA knowledge
...em-cell therapy, and oceans of ignorance about the workings of our bodies in sickness and in health." While many of the celebrations held this year have focused on the science surrounding the discovery 50 years ago, the UCSD symposium will emphasize the translation of genetic and genomic knowledge to the pati...Beyond biology: Simple system yields custom-designed proteins
...s Seho Kim and David Fela. Nearly all the internal workings of living things are built from proteins. While genes are the "blueprints" for organisms, proteins are the products built from those instructions. The molecules that transmit signals in the brain, carry oxygen in the blood and turn genes on and off a...Digital Biology Week: Building a national infrastructure for biomedical computing
...imulations that accurately model the complex inner workings of the human brain and other vital organs? What are the scientific and technical roadblocks that researchers will need to overcome in order to achieve such goals? These are just some of the key questions that top experts in biology, medicine, comput...Newly identified gene may halt fuzzy, moldy fruit
...ut he said he believes understanding the molecular workings of plants' natural methods of fighting off disease is the best way to overcome pathogens. The BOS1gene appears to control other genes and seems to provide resistance to several types of stresses. In other words, it controls a number of different gene...Mathematical modeling predicts cellular communication
... modeling can offer powerful new insights into the workings of complex signaling systems, cutting through the static to pick up important signals even in those pathways that are well understood. The results have important implications for developmental biology and human disease: The Wnt pathway is often activ...Illinois professor wins Nobel Prize
...y insights into the functions of the brain and the workings of the human body." Lauterbur was among the first scientists to use nuclear magnetic resonance in the studies of molecules, solutions and solids. He was the first researcher to produce an image with NMR and apply the technology to medicine. This led ...Targeting transcription: New insights into turning genes on
... coworkers have gained important insights into the workings of gene-activating transcription factors. They recently discovered that the gene-activating power of a transcription factor likely depends on where the factor binds to the cell's transcriptional machinery, as well as on how tightly it binds. Previous...New principle guides memory dynamics
...led accuracy. A new fundamental rule governing the workings of the brain, recently discovered by a team of scientists in the Weizmann Institute of Science, headed by Prof. Yadin Dudai of the Neurobiology Department, constitutes a step towards reaching this goal. Every memory that we acquire undergoes a "ripe...Genes that paint fly derrieres hint at convergence
...milar to melanogaster." By comparing the molecular workings of the captured fly, and other fly species snared or otherwise acquired by Gompel, the Wisconsin group was able to find genetic commonalities across 13 species covering the various branches of the fruit fly family. They found that a common gene know...'Mimics' may open screen(ing) door to GPCR drugs
...-resolution structural tools to study the detailed workings of rhodopsin and other members of the superfamily of membrane proteins called G-protein coupled receptors (GPCRs). In the journal Biochemistry, Kevin D. Ridge and co-authors describe a new approach for structurally characterizing functional regions o...Chemists unlock secret to activating tumor suppressor gene
...With this newly reported knowledge about the inner workings of PTEN, Cho hopes a way will be found to treat patients with damaged or mutated PTEN genes. Loss of PTEN action causes the cancer, Cho explained. To treat this condition, one must add the PTEN gene to the cell which lacks it, but the resulting PTEN...Insulin study sheds light on physics of crystal growth
...elp scientists design new drugs and understand the workings of the body and diseases. Crystallized materials also are key components in the next generation of computer chips, as well as in lasers used in nuclear fusion and nuclear weapons research. In a new study focusing on the physics of crystal growth in t...Hebrew University researcher wins prize for work leading to new anti-cancer drugs
... year for the awards. Kosloff has analyzed the workings of the Ras protein that is found in all cells of the body. Mutant, defective Ras is involved in up to 30% of human cancers. In healthy tissue, Ras is a master switch controlling cell division and proliferation. It cycles between an "off" state that s...'Work stinks': It's more than just a slogan among ants, researchers find
...even being used to unravel secrets about the inner workings of the mind. "A brain consists of units called neurons, none of which can make any global assessments, and yet somehow in the aggregate, lots of neurons together manage to think and remember," Gordon explained. "We hope that by learning more about ho...