Researchers discover structure of Nature's 'circuit breaker'
... many new details about the architecture and inner workings of potassium channels -- the voltage-sensing mechanism remained a frustrating mystery. "The general principle was understood that the electric field on the membrane somehow moved 'gating charges' on the channel that would somehow open it to allow pot...MacKinnon lab's newest picture tells action potential story
...the Rockefeller scientists have revealed the inner workings of sodium and potassium channels, or the why's and how's of ion movement through a cell's membrane. What this earlier research did not do, however, was explain how a fundamental feedback loop worked. Now, with the structure of the voltage-dependent ...Researchers determine fundamental mechanisms involved in immune response
...us foreign pathogens. The findings also reveal the workings of a gene mutation process that can go awry, leading to the development of certain forms of cancer or allergic reactions. HHMI investigator Frederick W. Alt at Children's Hospital in Boston and Harvard Medical School directed the studies. His team'...Brain imaging study sheds light on inner workings of human intelligence
...nd colleagues devised a study to explore the inner workings of one important aspect of human intelligence. The study sought to better understand the process through which the mind reasons and solves novel problems, an ability known among psychologists as fluid intelligence. The results may help researchers to...Scientists crack the black box of coastal ecosystems
...ack box of coastal ecosystems, revealing the inner workings of the near-shore marine environment. Working on a scale from microscopic fish larvae to the 1200 mile long California Current that sweeps the west coast of the United States, an interdisciplinary team of over 100 ecologists, oceanographers, genetici...Puzzle solved on how influenza builds its infectious seeds
...t virulent diseases. This insight into the genetic workings that underpin infection by flu, reported today (January 27, 2003) in the Proceedings of the National Academy of Sciences (PNAS), provides not only a better basic understanding of how flu and other viruses work, but holds significant promise for new a...Deadly coral toxin exposes ion pump's deepest secret
...Prilosec. A better understanding of the molecular workings of ion pumps may ultimatelypave the way for better treatments for hypertension and heart failure, andpossibly other disorders. "We hope that palytoxin will give us a more detailed picture of themolecular mechanisms underlying the function of one of ...Powerful technologies probe innate immunity
...ween biology and information science to fathom the workings of innate immunity. Knowledge generated could help scientists develop treatments for septic shock, certain autoimmune disorders and diseases caused by potential agents of bioterrorism. Daniel Rotrosen, M.D., director of NIAID's Division of Allergy...Genes, neurons, and the Internet found to have some identical organizing principles
...ndamental laws governing our bodies, rendering the workings of a cell fully evident and the means of repairing it clear cut. One day in the distant future, scientists hope, doctors' work will be comparable to that of present-day electronic engineers. They will analyze blueprints of malfunctioning cells and th...NSF establishes center for biophotonics at UC Davis
...the science of using light to understand the inner workings of cells and tissues in living organisms. The center will be announced in a press conference on the UC Davis campus today, Oct. 24. Applications of biophotonics range from using light to selectively treat tumors, to sequencing DNA, biochemical stud...Energy Department awards $103 million for post-genomic research
...es. Scientists have long tried to understand the workings of individual genes or small groups of genes. The...mice -- that provide new perspectives on the inner workings of biological systems. The project's 10-year goal is to make advances in systems biology, computatio......unds that they were "subsidised" and disrupted the workings of the free market. "It's been disastrous," he says. "We can't sacrifice food security on the altar of free-market economics."...NIGMS energizes NMR research with world's biggest magnets
...o have faster, more accurate glimpses of the inner workings of molecules and to study ever-larger molecules, rolling back a major limitation of the technology. The National Institute of General Medical Sciences will support the construction of four new custom-built 900 MHz NMR magnets--the largest size availa...Genetic fingerprint of lung cancer predicts treatment outcome
...once provides unprecedented insight into the inner workings of individual lung tumors. "The goal is to further refine the fingerprint and eventually produce a lung cancer-specific microarray for testing in clinical trials," said Dr. Frances Shepherd, the Head of the Lung Cancer site group at University Health...HHMI selects new clinical investigators
...gy that have revealed new concepts about the inner workings of the human cell, said Joseph L. Goldstein of the University of Texas Southwestern Medical Center at Dallas and chairman of HHMIs Medical Advisory Board. What are crucially needed are more patient-oriented researchers with the expertise to translate...Traits link viruses from common cold to HIV
...nt virus groups." On the surface, the reproductive workings of viruses are extremely complicated as, over time, they have evolved subtle and intricate ways to camouflage themselves or otherwise circumvent the immune defenses of their hosts. Finding common threads, says Ahlquist, means it is possible to genera...Tidying up transcription factors
...ately lead to new and important concepts about the workings of the cell....Researchers link gene to hereditary form of prostate cancer
... new finding presents a tantalizing clue about the workings of the complex genetic machinery that leads to this common cancer." "It has been clear for some time that hereditary factors play a major role in prostate cancer risk," added Francis S. Collins, M.D., Ph.D., director of the National Human Genome Res...Lehigh scientists believe they have found link between DHEA and central nervous system
...cause-and-effect relationship between DHEA and the workings of the body's central nervous system. Neal Simon, chair of the biological sciences department at Lehigh, says he and his colleagues have discovered the "genomic effect" of DHEA, or its influence at a cell's genetic level. By contrast, says Simon, mo......ht on the still relatively poorly understood inner workings of human, bacterial, fungal, and tumor cells. "This has important implications for our continued fight against many human ailments," Romo said, "because the more we know about how cells work, the better we will be equipped in controlling the activity...