MCG pursues markers to improve ovarian cancer treatment, diagnosis
... one point increase means their disease is getting worse and they will have to go through treatment again," Dr. Dickman said. "We want to give them better options."...Glowing microspheres improve fluorescence measurements
...a sample can indicate whether a disease is getting worse or is in remission. Until now, the intensity of the signal, reflecting numbers of target molecules, has been judged visually or with benchmarks developed by individual manufacturers. Previous research has shown that measurements of the same samples c...AChemS: Cutting edge research in taste, smell, & chemical irritation
...ow air pollution). Mexico City residents performed worse on all tests. [ Read More ] The Bigger, the Better? Not in Olfaction! Recent studies demonstrate that human and nonhuman primates show an olfactory sensitivity which for several substances matches or even is markedly better than that of species s...JCI table of contents, 15 March 2004
...instead of an amelioration of RA, the mice had far worse RA symptoms, indicating that instead of increasing RA risk when present, CCR2 play some protective role in RA. This study indicates clearly the complexity of the molecular interactions involved in the development of RA and indicates the need for cau...Faulty DNA replication linked to neurological diseases
...will get still longer. And the longer it gets, the worse the disease," Mirkin said. "Basically, even if you are more or less okay, there is a probability that your kids will be sick and a still higher probability that your grandkids will be even sicker." To study how and why the inherited sequence expands ...Gene predisposes infants to neurologic injury after heart surgery
...tein E gene were significantly more likely to have worse neurodevelopmental outcomes at age one, compared t...igher risk of suffering Alzheimer's disease and of worse recovery after brain injury or cardiac surgery. However, the researchers did not find that APOE e4 h...Pew report finds GM insects may offer benefits, but clear regulatory oversight is lacking
...ion, potentially making pre-existing pest problems worse or creating altogether new challenges. It is also possible that GM insects released to control the spread of disease could actually have the unintended consequence of enabling an insect to more effectively spread disease or even carry a human diseas...Research reveals brain has biological mechanism to block unwanted memories
...eline group for a half-hour. "People's memory gets worse the more they try to avoid thinking about it," Anderson said. "If you consistently expose people to a reminder of a memory that they don't want to think about, and they try not to think about it, they actually don't remember it as well as memories wh...Asthma could be several diseases masquerading as one
...he late-onset patients, lung function was slightly worse in the late-onset group. That suggests that patients with late-onset disease suffer a more rapid loss of lung function. The pattern of inflammation also differed depending upon the age of onset. Late-onset patients were more likely than early-onset ...HPV testing could be future strategy for primary screening for cervical cancer
... HPV testing was more sensitive than borderline or worse cytology (97% compared with 77%) but slightly less specific (93% compared with 96%) for detecting malignant cells. Surveillance at 12 months was as effective as immediate colposcopy for women with minimal abnormalities, i.e., those women with either ...Communication is key to successful U.S. SARS quarantine
...ies in more than 25 countries. "It could have been worse without aggressive public health measures." SARS was a new virus that struck unexpectedly and the countries affected had little time to plan a response, Rothstein said. To combat the epidemic, the countries studied in the report imposed large-scale q...New pathway discovered at Stanford provides insight into heart disease
... of the study. In other words, the things that get worse during heart failure improve with the aid of an LVAD. Genes that change during the recovery process could provide valuable insight into the progression of heart disease because heart tissue after LVAD use approximates the patient's healthy heart. Th...Gene raises risk of neurodevelopmental problems after infant heart surgery
...ene variant were significantly more likely to have worse outcomes in a developmental evaluation of cognitive and motor skills compared to children who underwent heart surgery and did not have the APOE2 gene. APOE2 occurs in approximately 8 percent of the population. Apolipoprotein genes, which help to regu...Poor prognosis linked to BRCA1 mutations
...survival rates for women with BRCA1 mutations were worse than those without mutations (38% of carriers died compared with 14% of non-carriers). However, the presence of a BRCA1 mutation did not reduce long-term survival if the women were treated with chemotherapy. Risk factors other than the mutations are ...When heme attacks: After trauma, the molecule that makes life possible rampages
... free-floating heme can also make traumatic events worse by damaging tissue. The Penn researchers present their findings in the October 2nd issue of the journal Nature. Fortunately, the researchers also identified a chemical that can be targeted by drug developers to impede the deleterious effects of free...Asthma patients cautioned about melatonin
...ncreases inflammation in their airways, leading to worse lung function," said Dr. Sutherland. "Given that previous work has shown that melatonin promotes inflammation in the cells of both nocturnal and non-nocturnal asthmatics, any person with asthma should be cautious about taking supplements that would f...Telltale prostate cancer protein key to breast cancer, too
...re EZH2 there was, the deadlier the cancer and the worse the patient's outcome. The new results linking EZH2 to breast cancer, and describing the mechanism of its role in cancer's spread, are based on exhaustive analysis of tissue samples and medical records from 280 U-M breast cancer patients, and studie...Sleep disorders linked to faulty brain chemistry, study finds
...ine and acetylcholine. The greater their lack, the worse their sleep problems were. The patients with the fewest dopamine-producing neurons in the striatum of their brains had the worst RBD symptoms of thrashing, talking and violent flailing while they slept. And patients with the lowest levels of acetylc...Scientists say 'save our seas'
...ng areas. Coastal erosion is also expected to get worse due to increased storminess. Fish stocks in the North East Atlantic have declined during the past decade and ICES research has showed that, out of 113 stocks assessed in 2001, only 18 per cent were inside safe biological limits. Oil discharges ...... with higher levels of mercury in their hair fared worse on the tests for motor skills, memory and concentration. Mercury is used in small-scale gold-mining. A gold-rush began in the Patanal region of Brazil in the early 1980's, leading to an increased concentration of mercury in the environment in the mi...