Research teams uncover risk genes for multiple sclerosis
..., including preventing the bodys immune cells from attacking its own tissues. This analysis confirmed that link while also finding other variants in genetic regions that are more common in people with MS. Scientists are increasingly finding genetic links between autoimmune diseases that affect different tis...Risk genes for multiple sclerosis uncovered
..., including preventing the bodys immune cells from attacking its own tissues. This analysis confirmed that link but went further to find other variants in genetic regions that are more common in people with MS. One of the regions contains a gene called the IL-2 receptor, which has also been linked to two ot...New research identifies anti-viral protein that may predict who might be at risk to develop lupus
...oesnt know self from non-self anymore turning and attacking its own tissue as in SLE. As far back as the 1970s, doctors had known that a characteristic of patients with SLE, who are mainly women in their childbearing years, was an abnormally high blood level of interferon-alpha. However, they didnt know if...JCI table of contents -- July 26, 2007
... and arthritis result from the bodys immune system attacking its own tissues or self antigens. Therefore, researchers have long desired to understand how a state of immune tolerance (the inability to mount an immune response against an antigen) may be forcibly induced as a therapeutic approach to treating auto...MIT IDs link between brain tumor proteins
...n the tumor cells, and they have demonstrated that attacking both of those proteins kills tumor cells much more effectively than targeting either one alone. The researchers, led by Forest White, MIT associate professor of biological engineering, report their findings in the early online edition of the Procee...Immune system 'escape hatch' gives cancer cells traction
...eep the immune system in check and prevent it from attacking otherwise healthy tissue, can suppress the anti-tumor response to cancer. These suppressor cells block other immune system cells, CD8 killer T cells, from binding with proteins that identify the foreign antigens on the surface of unhealthy cancer...Aphids make 'chemical weapons' to fight off killer ladybirds
...mical defence system which enables them to disable attacking predators by setting off a mustard oil bomb, says new research published today. The study shows for the first time how aphids use a chemical found in the plants they eat to emit a deadly burst of mustard oil when theyre attacked by a predator, for...Scientists follow familiar TRAIL to new cancer therapy
...b/Nexavar, thus providing an exciting approach for attacking cancers that harbor defective intrinsic apoptotic machinery, explains Dr. El-Deiry. ...From clinical cancer research: rethinking therapeutic cancer vaccine trials
...e designed to rile the patients immune system into attacking tumor cells. In their review Schlom and his colleagues looked at two cell-based vaccines, Sipuleucel-T (Provenge) and GVAX, as well as three trials using an engineered pox-virus vector. While this review article focuses on prostate cancer vaccines,...New approach to pulmonary hypertension shows promise
...ingle problemactivation of NFAT. "Therefore, by attacking NFAT, the 'common denominator' of these abnormalities, you might be able to treat them all at once," he said. In January this year, the same U of A research team published a paper announcing a possible new treatment for various types of cancer usin...Invertebrate immune systems are anything but simple, conference finds
...ft unchecked, can harm an individual by mistakenly attacking cells in the body. In humans, the failure of the body to recognise itself results in autoimmune diseases. For example, Crohns disease is the failure of the body to recognize intestinal cells, resulting in an immune response against these cells....Marine phytoplankton changes form to protect itself from different predators
...t large, ball-shaped colonies. When copepods are attacking the phytoplankton, therefore, the best survival st...organism responds to the chemical signals of whats attacking it, Hay said. Experimentally, the researchers attempted to separate the chemical signals from the ...Hives ferment a yeasty brew, attract beetle pest
...y Collapse Disorder, a multitude of things are all attacking bees today, these beetles are just one more thing to add to an already embattled species," says the Penn State researcher. ...New Brandeis research sheds light on memory by erasing it
...new research shows how synapses can be weakened by attacking memory molecules. Lisman's lab plans further research to better understand what happens to the CaMKII after it is attacked. By using fluorescent forms of CaMKII, it will be possible to determine whether the kinase leaves the synapse after inhibito...Discovery of new family of pseudo-metallic chemicals
...es and might change the way scientists think about attacking disease or even building electronics. Five decades ago, Fred Hawthorne, professor of radiology and director of the International Institute for Nano and Molecular Medicine at MU, discovered an extremely stable molecule consisting of 12 boron atoms a...JCI table of contents -- April 19, 2007
...eumatoid arthritis are caused by the immune system attacking the bodys own tissues. Determining the factors that trigger the immune system to attack is an area of intensive research. In a new study appearing online on April 19, in advance of publication in the May print issue of the Journal of Clinical Investi...Enhancing chemotherapy's efficacy: New agent has synergistic effect with standard drugs
...k in different ways, such as damaging their DNA or attacking the cells' architecture. Several widely used drugs, including paclitaxel (Taxol), docetaxel (Taxotere) and long-time standby vincristine, take the latter approach, targeting important cell components called microtubules. "Very few clinical agents ar...Researchers discover connection between allergic diseases and autoimmune diseases
...ding B and/or T immune cells) becomes misdirected, attacking the very organs it was designed to protect. "Our study implies that allergic and inflammatory diseases may actually trigger autoimmune diseases by relaxing the controls that normally eliminate newly produced, self-reactive B cells. This is importan...Spiders: Chastity belts stop cuckoos in the nest
...y puts an end to the affair after a few seconds by attacking her partner and killing him if he does not escape in time. When the male detaches himself from the female, in more than 80 per cent of cases the tip of his genital breaks off, the Bonn lecturer Dr. Gabriele Uhl says. The tip then remains in the sexua...Researchers begin 'Project 3000,' a recipe for hope through genetic research
...st objective and become the "blueprint" recipe for attacking dozens of other sight-robbing diseases. Based at the UI Carver College of Medicine, Project 3000 will offer state-of-the-art genetic testing to identify individuals on a nonprofit basis through the John and Marcia Carver Nonprofit Genetic Testing L...