New therapy for specific form of leukemia
.... Leukemia appears in several forms − in the case of T-ALL, a large accumulation of immature white b...s a number of processes in the cell − in the case of ABL1, this is the process of cell division. It is crucial that kinases function in a very control...An embryonic stem cell model for Parkinson's disease
...S Biology , Asa Abeliovich and colleagues make the case that a model based on mouse embryonic stem cells offers a promising platform for dissecting the disease mechanism of Parkinson's. Working with these cells, the researchers created dopamine neurons deficient in DJ-1, a gene mutated in an inherited fo...Pine cones lead to a fundamental change in clothing
...ss to match the changing temperature. Often it's a case of being too hot or too cold, or taking a jumper on and off. "The new smart clothing will make all that unnecessary and we're pleased to combine our expertise in technology with cutting-edge clothing design. "We've drawn upon nature to...Intelligent clothing inspired by pine cones
...ss to match the changing temperature. Often it's a case of being too hot or too cold, or taking a jumper on and off. "The new smart clothing will make all that unnecessary and we're pleased to combine our expertise in technology with cutting-edge clothing design. "We've drawn upon nature to come up with a...Dying cells encourage neighbors to grow
...gulation of apoptosis, as has been shown to be the case in some cancers, may result in pathological activation of these pathways. "Based on the behavior of undead cells in Drosophila imaginal discs, one might expect mutations that block or delay apoptosis to cause secondary proliferation and hyperplasia. ...September/October 2004 Annals of Family Medicine tip sheet
...ent) or heart attack (97 percent). However, in the case of a minor foot operation, only 33 percent wanted ...ipated needing contact as well: 81 percent in the case of a birth within the family and 90 percent in the case of a death in the family. Qualitative interv...MIT: Recycling of scrapped electronics studied
...ecycler paid or was paid to take it away. In case studies of three U.S. firms, the researchers found that the value-based metrics worked well and were easy to use. The researchers stress that their materials-only analysis is just a baseline and does not incorporate the effect of device or component ...Children's Hospital Boston wins $2.5 million in health surveillance grants
...ents can become overwhelmed by the large number of case investigations and public inquiries," notes Advani. "This automated system will allow health agencies to rapidly enhance their capabilities during outbreak emergencies." This the first time that the CDC is making research grants to academic scientist...Highlights of American Anthropological Assoc. meeting
...gining the "Urban": San Francisco is examined as a case study of how traditional concepts of urban versus suburban have changed. (Noon1.45 p.m.). Anthropological Approaches to Central Asia and the Middle East: Scholars working on both sides of the Atlantic discuss new approaches to replace notions ...UT Southwestern researchers uncover process for sugar-induced fat formation
...n genes on and off in response to a signal. In the case of ChREBP, the signal is glucose, a simple sugar formed when carbohydrates are broken down during digestion. Glucose enters the bloodstream and, through transport molecules, enters cells where it is broken down into even smaller pieces. These smaller......e colourful 'auras' around their loved ones. The case study, reported in the October issue of Cognitive ...th the person's name or face. In contrast, a case discovered in the 1930s documents a seven year old boy who also associated colours with people, but ...Mice thrive despite massive genetic makeover
...m a novel and still follow the story line? In the case of the mouse's genome, or "book of life" -- and perhaps even our own -- the answer appears to be, astonishingly, "yes." Researchers from the U.S. Department of Energy Joint Genome Institute (JGI) and Lawrence Berkeley National Laboratory demonstrated...OHSU study: Bacterial switching mechanism key to survival
...ntibiotics, which disrupt those functions." In the case of the Cell study, an antibiotic could be developed to disrupt the HPr-CcpA interface, rendering the bacteria dysfunctional but not necessarily dead. "They would then be at a great disadvantage," Brennan said. "They would be less competitive and not...Molecular mechanism sheds light on neurodegenerative diseases
...al time that the toxic protein aggregates, in this case caused by mutant Huntingtin, bind to the proteasome machine irreversibly and prevent the complete degradation of the proteins. This evidence could help explain the disease process. "We believe this suggests why Huntington's disease is so destructive,...Are yeast cells bringing us a step closer in treating obesity?
...he cell. The chance is great that this is also the case with human cells. Because about 40% of today's medicines act on receptors in our cells, this research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity. Detecting sugars in the cell Every living thing is ......nce from the total of 548 families strengthens the case for EN2 as an autism gene. The EN2 gene encodes a protein called a transcription factor that binds to cells' DNA to control the expression of dozens or even hundreds of other genes. Therefore, a variation in EN2 could have far-reaching effects...Early life stress harms mental function and immune system in later years
... of adult mice, and how experience--hunting in the case of barn owls--can dramatically increase adult animals' adaptability to new stimuli. Together, these studies point to exciting new approaches for potentially lessening or preventing these long-term changes that can lead to disease or psychopathologies...Pesticides may promote Parkinson's disease and exercise may offer protection
...y to the animals over a period of 18 months in one case and 19 months in the other before the Parkinson's-like pathology developed. When the monkeys' brains were later examined, the scientists found anatomical and biochemical changes virtually identical to the major abnormalities seen in Parkinson's disea...Insects implicated in the evolution of new human infectious diseases
...h as malaria into the Northern hemisphere." In the case of Photorhabdus luminescens, the infection is naturally resistant to several antibiotics but the relapsing infection can be combated using repeated administration of certain drugs. The researchers predict that the failure of automated hospital diagn......risk for local populations. Their results make the case that mathematical models can help public health officials calculate risk of infectious diseases in heterogeneous environments--that is, real world conditions--when vector ecology and the parameters of transmission are well characterized. Any plan to ...