Tag: "cloned" at biology news

Clones on task serve greater good, evolutionary study shows

...keeps you in the zone. The group studied different cloned offspring of the Arabadopsis, a plant of the mustard family commonly used to test genetic questions. Arabadopsis can have many offspring that are genetically identical. Yet, just like human twins, these identical plants still have subtle individual d...

Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols

...tically generate RNA molecules in vitro, using the cloned gene of interest as a template. The RNA molecules are then randomly cleaved into short fragments, purified, and used in RNA interference experiments. The procedure was developed by Dr. Frank Buchholzs group at the Max Planck Institute of Molecular...

Fedoroff, of Penn State, to receive National Medal of Science

...application of molecular techniques to plants, and cloned some of the first plant genes. She then undertook...bel laureate Barbara McClintock in the 1940s. She cloned the first complete maize transposon and went on to study the molecular mechanisms that control the m...

Cloning the male genome may help infertile men

...vel of abnormalities consistent with that shown in cloned animals. Where the man in a couple has problems ...hich the nucleus had been removed, and by doing so cloned the male genome. The process worked well in almost all cases and the sperm genome was found to be ...

Cloned pigs help scientists towards a breakthrough in Alzheimer's

... the cutting edge of biotechnology. This time with cloned pigs that have been genetically modified so that they may function as animal models for the notorious Alzheimers disease. In the US alone, 5 million people suffer from this human brain disorder and globally the number is set at approx. 24 million ...

Banding together: RAS signaling of circadian output

...lleagues at Dartmouth Medical School, have finally cloned the band gene, and have found that it is an allele of ras-1. This finding posits RAS signaling as a key mediator of circadian output. The fungus Neurospora crassa is one of the best studied laboratory systems for circadian rhythms. However, over th...

MIT-led team uncovers malaria mechanism

...ell surface. In this experiment, the researchers cloned the parasite and then knocked out the gene that produces RESA and then measured the red blood cells' deformability with "optical tweezers," which use lasers to stretch cell membranes. They found that in red blood cells infected by parasites without...

Biosensor sniffs out explosives

... fluorescent protein. Into these yeast cells, they cloned individual rat olfactory receptors. When the olfactory receptor "smells" the odor of DNT, an ingredient in the explosive TNT, the biosensor turns fluorescent green. The research team is the first to identify, clone and sequence this novel olfactory r...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...s Medical Institute investigator at Duke who first cloned these receptors in 1986. The link was cemented through a collaboration with Matt Foster, a post-doctoral fellow in the laboratory of Jonathan Stamler M.D. G-protein coupled receptors reside on the cell surface where they interact with all manner of...

News tips from the Journal of Neuroscience

...exinA3 in primary motor axon guidance. The authors cloned plexinA3 from zebrafish and demonstrate its expression at the ventral edge of the embryonic spinal cord, specifically in the caudal and middle primary motor neurons (CaP and MiP), the axons of which regularly exit the spinal cord. Translation-blockin...

Veterinary scientists explore poultry virus as cancer killer

...the process of generating a recombinant virus from cloned complimentary DNA (cDNA) copy of a viral genome, explains Subbiah. Through the reverse genetics system, recombinant viruses can be designed to have specific properties that make them attractive as biotechnological tools, live vaccines, and cancer the...

New science of metagenomics 'will transform modern microbiology'

...of millions of random fragments of DNA that can be cloned into a form capable of being maintained in laboratory bacteria. These bacteria are used to create a "library" that includes the genomes of all the microbes found in a habitat, the natural environment of the organisms. Although the genomes are fragm...

Epigenetic studies will provide a better understanding of disease

...igenetic differences explain, for example, why two cloned organisms are not the same or why twins develop illnesses of distinct genetic origin. Epigenetic studies promise not only to have a direct impact on health and our understanding of the relations between the environment and genetics but also to provid...

DNA gives new perspectives to understand the mysteries of nature

... particular piece of DNA is then being multiplied, cloned and sequenced, which makes it possible to be identified by the researchers. However, this present procedure is slow, and it takes years just to identify a fraction of the most common animals and plants available from the DNA in the many samples. A...

Mice cloned from skin cells

...ive until adulthood have, for the first time, been cloned from adult stem cells. Scientists from Rockefeller...ademy of Sciences. A number of laboratories have cloned mice using cumulus cells (cells that surround and support a developing egg) or fibroblasts (connecti...

Scientists clone mice from adult skin stem cells

...ch is simpler and more efficient than generating a cloned mouse. Although this procedure has not yet successfully generated human embryonic stem cell lines, once technological hurdles are overcome, it may be possible in the future to use a patient's skin stem cells to tailor make embryonic stem cell lines, ...

Scripps Research study reveals new function of protein kinase pathway in tumor suppression

...p38 field, Professor Jiahuai Han. The p38 gene was cloned by Han in 1994. Since then, the Han lab has identified some p38 downstream protein kinases, including PRAK, and has shown that PRAK can be activated by various stresses. The Han research group also engineered PRAK knockout mice, animals that lack the...

UCLA and NYU microbiologists crack genome of a parasite that causes a common STD

... issue of the journal Science. "Patricia Johnson cloned the first Trichomonas vaginalis gene in 1990 as an assistant professor at UCLA, and it is tremendously gratifying that she is now senior author on a landmark publication describing the entire genome," said Jeffery F. Miller, chair of microbiology, im...

Imaging techniques permit scientists to follow a day -- or 4 -- in the life of a cell

...hnique is similar to those that are used to create cloned and transgenic organisms, and it can also be applied to more complex assays--including laser photobleaching and fluorescent speckle microscopy--that yield specific insights into cellular processes. A second freely available protocol ( http://www.cs...

McBride shows DNA detective work with paper-eating bacteria that 'glide'

... of gliding bacteria for more than a decade. They cloned "mutants" of F. johnsoniae that are unable to move, and then attempted to "repair" them by inserting certain pieces of DNA. In this way, they have uncovered nearly all the genetic components that propel the cells. It has been a long process. A decad...

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(Date:7/30/2014)... of America (ESA) has elected ten new Fellows of ... acknowledges outstanding contributions to entomology in one or more ... following Fellows will be recognized during Entomology 2014 -- ... November 16-19, 2014 in Portland, Oregon. , DR. ... Department of Plant, Soil and Entomological Sciences at the ...
(Date:7/30/2014)... Jackson Laboratory has received a pledge of $1 million ... name the Laboratory,s new Neurobehavioral Biometry Center. ... Center will enable the Laboratory to develop a greater ... the ultimate goal of accelerating the pace of research ... serve as a premier resource for the Laboratory and ...
(Date:7/30/2014)... changing climate threaten some of the world,s most ... establish seed collections to save the seeds in ... some genetic diversity., For decades, these seed collections ... a one-size-fits-all approach for how many seeds to ... regardless of species, pollination mode, growth habitat and ...
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