American Chemical Society's Weekly PressPac -- Aug. 8, 2007
...g, changing color in the presence biogenic amines, compounds produced by the bacterial decay of food proteins. In laboratory tests, the polymer identified and distinguished between 22 different kinds of key food-spoilage amines with 97 percent accuracy. Researchers also used the polymer to check the freshness ...OHSU turns mouse into factory for human liver cells
...aceutical industry uses for testing candidate drug compounds is estimated at $2 billion a year, according to a ...nimals because liver enzymes that break down these compounds are species specific. "Animal liver cells process drugs quite differently than human liver cells do,...Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...t helps other proteins to fold properly. These new compounds can tether bulky chaperones to the beta-amyloid fragments and prevent them from forming large clumps. As a result, these molecules are effective at reducing protein clumping at concentrations 100 times lower than other blocking agents that have been ...Antioxidant overload may underlie a heritable human disease
...times referred to as antioxidants, are elements or compounds that easily give up an electron to become oxidized, while oxidizing agents readily accept electrons. In the body, such oxidation-reduction (redox) reactions are integral to the release and storage of energy. Many cellular pathways are also sensitive ...New study suggests Concord grape juice may provide protection against breast cancer
...t issue of the Journal of Medicinal Foods, natural compounds in Concord grape juice protected healthy human bre.... However, the introduction of Concord grape juice compounds blocked the connection of the carcinogen to the DNA of the healthy cells. The purple grape compo...Grapes, soy and kudzu blunt some menopausal side effects
...ve been sought. Certain naturally occurring edible compounds found in plants dietary polyphenols have been shown to have some beneficial effects similar to HRT but without the appreciable adverse effects. Grape, soy and kudzu are dietary polyphenols. One research lab investigating them through several studie...Role of thyroid hormones in slumber under investigation at Rutgers
...urements of the levels of thyroid hormones and the compounds which are derived from them in the brain during circadian rhythms and during sleep and waking. Additional research will include observations of the effect of microinjections of thyroid hormones in sleep-related brain structures of rats. As in the ...American Chemical Society's Weekly PressPac -- Aug. 1, 2007
...edications that are combined with certain chemical compounds that respond to light in ways that release precisely controlled amounts of the drug. Drug release begins when light falls on the compounds, and lasts only as long as the light continues to shine. The study reports successful laboratory tests of the...UCF research links proteins, stem cells and potential Alzheimer's treatment
...ells. Sometimes that may mean coming up with other compounds that help deliver the therapy. ...... to cause disease. The next step will be to screen compounds that could potentially block the action of this ge...ne. As a first step, U-M scientists plan to screen compounds to find ones able to block specific processes they have identified in the anthrax microbe....Native fruits bear sweet antioxidants
...ies. Studies to identify additional antioxidant compounds as well as clinical trials for testing the fruits bioactivity in vivo, are in progress. he says. While Australian native fruits have been eaten by indigenous people for thousands of years, this is the first scientific study of the fruits as a sour...American Chemical Society's Weekly PressPac -- July 25, 2007
...es from lab to clinic. The use of small molecules compounds that include most drugs to generate new nerve cel...ort notes, had predicted that certain metabolites compounds formed in the bodies of people exposed to diesel exhaust should appear in the urine. One of those c...Geisinger scientist seeks cure for Lou Gehrig's disease, creating device to find treatment
...in the right mix of the millions of drugs and drug compounds that have been developed in laboratories across the world. There are so many different compounds but you dont know which ones to test, Gerhard says. We need bioengineering help to automate this pro...MIT model could predict cells' response to drugs
... and could help drug developers identify the ideal compounds on which to focus their research. In addition, the model could help test the effectiveness of drugs for a wide range of diseases, including various kinds of cancer, arthritis and immune system disorders, according to Douglas Lauffenburger, MIT pro...GI Caramba! Blue tortillas may help dieters and diabetics
...s in the corn. These are the same health promoting compounds found purple berries and red wine....Faster-acting antidepressants closer to becoming a reality
...for weeks or months. The value of our research on compounds like ketamine is that it tells us where to look fo...ated experiment, the scientists used two different compounds instead of ketamine to try to block just one part of the NMDA receptor, an even more precise target....Coming soon -- Protein synthesis without amino acids?
...utely necessary to start from amino acids. Imines, compounds with a carbon-nitrogen double bond, could be an ideal starting materialif it were possible to link them together in an alternating fashion with a carbon monoxide molecule (CO), like a pearl necklace made of two different alternating types of pearl. T...Exercise, exercise, rest, repeat -- how a break can help your workout
...ncrease in free fatty acids and glycerol (chemical compounds that are released when stored fat is used) concentrations in the final 15 minutes of exercise, whereas these concentrations only progressively increased throughout the Single trial. Also, the second half of the Repeated trial showed a significantly ...American Chemical Society's Weekly PressPac -- July 11, 2007
...s, with implications for diabetes Healthful compounds in tomatoes increase over time in organic fields ... ARTICLE #2 FOR IMMEDIATE RELEASE Healthful compounds in tomatoes increase over time in organic fields Journal of Agricultural and Food Chemistry Level...Tips from the Journals of the American Society for Microbiology
...as a model for the development of chemotherapeutic compounds against tick-borne disease organisms. (N. Tsuji, B. Battsetseg, D. Boldbaatar, T. Miyoshi, X. Xuan, J.H. Oliver, Jr., K. Fujisaki. 2007. Babesial vector tick defensin against Babesia sp. Parasites. Infection and Immunity, 75. 7: 3633-3640)....