Children's Hospital Boston geneticist awarded for research on muscular dystrophy
...ildren's Hospital Boston and a well-known muscular dystrophy scientist, has received the major annual award given by the American Society of Human Genetics (ASHG). A pioneer in the field of human genetics, Kunkel was honored for nearly two decades of work on the genetics of muscular dystrophy, a family of here...National Eye Institute funds search for genetic key to corneal disease
...to narrow the genetic cause of one type of corneal dystrophy and to offer improved diagnosis of this family of ...ies of corneal dystrophy. "There are many types of dystrophy and it's difficult to discern them just by looking at them," Yee said. "Physicians will be able to ...JCI table of contents, December 1 2004
...an an animal model of cardiomyopathy and muscular dystrophy to determine whether these stem cells would be re...ress/22787.pdf Halting cell death heals muscular dystrophy The most common form of muscular dystrophy present at birth is caused by mutation of the LAMA2 gene...Zebrafish study yields observation of muscle formation
...oping new treatments for diseases such as muscular dystrophy and to treating muscle injuries. However, while sc...del system for development in general and muscular dystrophy in particular," says Henry....Zebrafish may hold key to understanding human nerve cell development
..., colon cancer, congenital heart defects, muscular dystrophy and other birth defects....... the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice. AUTHOR CONTACT: David M. Holtzman Department of Neurology, Washington University, St. Louis, Missouri, USA. Phone: 314-362-9872; Fax: 314-362-2826; E-mail: Holtzman@neuro.wustl.edu . This article is available at http://ww...Ophthalmologists and physicists team up to design 'bionic eye'
...ests in larger animals for which models of retinal dystrophy exist. The researchers are currently shipping chips to Joseph Rizzo, a professor of ophthalmology at Harvard Medical School, for implantation into pigs. Professor Mark Blumenkranz, chair of the Ophthalmology Department, advises the authors about surg...Scientists analyze chromosomes 2 and 4
...ase, polycystic kidney disease, a form of muscular dystrophy and a variety of other inherited disorders. Chromosome 2 is noteworthy for being the second largest human chromosome, trailing only chromosome 1 in size. It is also home to the gene with the longest known, protein-coding sequence a 280,000 base pair...Groundbreaking study shows adult stem cells have same ability to self-renew as embryonic
...ed while searching for a cure for Duchene muscular dystrophy (DMD), a genetic disease that is estimated to affe...,500 boys. DMD is the most common form of muscular dystrophy affecting children and patients often die in early adulthood because of heart damage. In addition to...Study in Royal Society journal on holly as an indicator of climate change
...viabilities (such as colour blindness and muscular dystrophy in humans) only when partners are of particularly high genetic quality, i.e., when the risk of having inviable offspring is reduced. Contact: Dr M Olsson, School of Biological Sciences, University of Wollongong, NSW 2522, Australia Journal of the R...$7.3 million NIH grant establishes Wellstone Muscular Dystrophy Research Center at the UI
...nal and clinical research on all forms of muscular dystrophy by providing resources and fostering collaboration...ffected individuals. The various types of muscular dystrophy differ in severity, age of onset, specific muscles affected and the rate at which symptoms progress....Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy
...ac muscle, too. Many people with Duchenne muscular dystrophy die in their 20s from heart failure caused by cardiomyopathy, a gradual weakening of the heart muscle. Heart failure is the second leading cause of death in DMD. The chemical sealant that protected hearts in dystrophic mice from damage is called polo...Research casts doubt on circulating stem cells
...issue. Even severe diseases like Duchenne muscular dystrophy (DMD), which destroys all the body's muscles, appeared to be potentially treatable indeed, by the simple means of transplanting healthy bone marrow. For boys, DMD is the second most common hereditary disease. Due to a genetic defect, the muscles fai...Nerve cells' power plants caught in a traffic jam
... why human neurological diseases, such as muscular dystrophy and spastic paraplegia, develop....No small feat: First ever gene therapy success for muscular dystrophy achieved
...e therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable s...apy ever being feasible for children with muscular dystrophy can be overcome. Moreover, their results, published in this week's online edition of the Proceedings...Hebrew U. / Johns Hopkins study provides clues to dealing with human disease
...minopathic diseases, such as progeria and muscular dystrophy in humans....Collaborations yield new discoveries in psychiatric genetics
...r blood type or found in such diseases as muscular dystrophy or cystic fibrosis. "The diseases we study are polygenic, meaning that many genes are likely to contribute, but how many genes there are and how they interact are unknowns," Millonig said. "Identifying a gene in a complex disease may give more insig...Cornell finds natural selection in humans
... negative selection are those involved in muscular dystrophy and in Usher syndrome, the most common cause of congenital blindness and deafness in developed countries. "We have a long way to go before we can predict from looking at sequences, which mutations in which genes and under which environmental conditio...Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
... tested AAV-8 in an animal model of human muscular dystrophy called limb girdle muscular dystrophy, or LGMD. In...f heart failure or other complications of muscular dystrophy around 37 weeks, while all of the AAV-8-treated LGMD hamsters survived beyond the 48-week duration o...Early cardiac screening necessary for muscular dystrophy patients
...ead to longer life in Duchenne and Becker muscular dystrophy patients, say experts at Baylor College of Medicin...major cause of mortality in patients with muscular dystrophy and is present in most boys with Duchenne muscular dystrophy and approximately 70 percent of those w...