Carnegie Mellon's Peter Adams receives EPA research grant
PITTSBURGHCarnegie Mellon Universitys Peter J. Adams has been awarded a $900,000 research grant from the Environmental Protection Agency (EPA) to study how global climate change and international pollution impact U.S. air quality. Spyros Pandis, a chemical engineering research professor, is a co-investigator on the grant. ... Adams, an associate professor of civil and environmental engineering...Story tips from the US Department of Energy's Oak Ridge National Laboratory, August 2007
... ... Oak Ridge National Laboratory research has aided in development of two new lines of wireless sensor products targeted at manufacturers by industry heavyweights Honeywell and General Electric. The instrument offeringsRF ValProbe by GE and OneWireless by Honeywellrepresent a new generation of wireless technology that taps industry-standard approaches to radio frequency identification, or...... That question may now be closer to an answer. By comparing computer models of damaged human DNA with micro...High rates of HIV infection documented among young Nepalese girls sex-trafficked to India
... Approximately 600,000 to 800,000 people are trafficked across the globe every year, and 80 percent of these individuals are estimated to be women and girls, according to the...Fish eyes could hold clue to repairing damaged retinas in humans
... Retinal damage is responsible for the majority of cases of blindness. Diseases damaging the retina including macular degeneration, glaucoma and diabetes are responsible for three quarters of registered blindn...Does EPA have an adequate strategy to oversee nanotechnologies?
... Former EPA...US Department of Defense awards $1.6 million for implantable biochip research
... ... Anthony Guiseppi-Elie, C3B director and Dow Chemical Profess...Nanowaste needs attention of EPA, industry and investors
... In addition, firms that manufacture nanomaterials, investors, an...Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process
... Researchers at the University of Illinois, Yale University and the Howard Hughes Medical Institute have shed new ligh...Chromosome glue repairs damaged DNA
... The new results are concerned with a phenomenon called cohesion, whereby two copies of a chromosome in the cell nucleus are held tightly together by a protein complex called cohesin. Cohesion fulfils an important function during cell division as the newly copied chromosomes, t...EPA foregoes opportunity to improve nanotechnology oversight
... According to former EPA official and Project on Emerging Nanotechnologies (PEN) senior advisor J. Clarence Davies, The agencys current practice is ina...Story tips from the Department of Energy's Oak Ridge National Laboratory
... The recently-opened Dell Regional Childrens Medical Center in Austin, Texas, is demonstrating the future in self-sufficient power, with the help of Oak Ridge National Laboratory. Working with researchers in ORNLs Buildings Technology Center, the medical facility has installed a combined heat and power system that delivers power to the facility at greater than 70 percent efficiency compared...Faulty cell membrane repair causes heart disease
... ... The study, led by UI researcher and Howard Hughes Medical Institute investigator Kevin Campbell,...CU researchers solve mystery of how DNA strands separate
Cornell researchers have answered a fundamental question about how two strands of DNA, known as a double helix, separate to start a process called replication, in which genes copy themselves.... The research, published in the current issue of the journal Cell, examined the role of an enzyme called a helicase, which plays a major role in separating DNA strands so that replication of a single stra...Scientists discover role of enzyme in DNA repair
... When DNA within a cell is damaged, the cells protective mechanism must do one of two things: repair the defect or commit suicide, says Rafael Casellas, Ph.D., an investigator in NIAMS Molecular I...Energy department selects 3 Bioenergy Research Centers for $375 million in federal funding
WASHINGTON, DC -- U. S. Department of Energy (DOE) Secretary Samuel W. Bodman today announced that DOE will invest up to $375 million in three new Bioenergy Research Centers that will be located in Oak Ridge, Tennessee; Madison, Wisconsin; and near Berkeley, California. The Centers are intended to accelerate basic research in the development of cellulosic ethanol and other biofuels, advancing P...Hepatitis B drug can compromise HIV treatment
... In findings published June 21, 2007, online in the journal, the researchers reported that a patient infected with both hepatitis B and HIV who was treated with entecavir developed a mutant strain of HIV that is resistant to the antiviral drugs lamivudine and emtricitabine. Entecavir is manufactured by Bristol-Myers Squibb and is ma...Innovative subsea separation technology wins 2007 EUREKA environmental award
Dutch and Norwegian project E! 3040 SUBSEA SEPARATOR has been presented with this years EUREKA Lillehammer Award for its outstanding environmental benefits. The award was handed over by Mr Einar BULL, Norwegian ambassador to Italy, at EUREKAs High Level Group gala dinner in Rome. This compact subsea processing equipment will ensure a better use of increasingly scarce resources and is set to impr...Herpes virus hijacks DNA repair process
June 13, 2007 -- Scientists probing the details of viral infection have discovered an intriguing surprise: in mice, herpes viruses hijack their host cells' tools for fixing DNA damage and use those tools to enhance their own reproduction. ... The DNA damage response normally fixes DNA errors caused by radiation or other environmental factors, or mistakes accidentally introduced when cells copy t...Enzyme crystal structure reveals 'unexpected' genome repair functions
The study is being published in an advance online version of the journal Molecular Cell. ...... The research looked at XPB helicase from an archaea, a single cell organism similar to bacteria. Helicases are enzymes that unwind or separate the strands of the nucleic acid double helix, an action that is critical to transcription and nucleotide excision repair (NER), as well as other cell processes....Hepatitis C therapy: Inhibiting newly discovered microDNA molecule
Last fall Dr. Peter Sarnow and a team of Stanford University scientists reported that the hepatitis C virus needs a specific microRNA, named miR-122, in order to replicate in cultured liver cells. When the scientists inactivated the microRNA, the amount of hepatitis C virus RNA was reduced by approximately 80 percent. The discovery was widely heralded for its potential to develop new antiviral...Stanford scientist to discuss new approach to treating hepatitis C virus
STANFORD, Calif. - Last year Peter Sarnow, PhD, professor of microbiology and immunology at the Stanford University School of Medicine, identified a previously unknown mechanism that the hepatitis C virus uses to replicate, yielding a promising new approach to combating the disease-causing virus. On April 5 at the Experimental Biology meeting in San Francisco, Sarnow will discuss recent developme...Energy and Agriculture Departments provide $8.3 million in funding for biofuels research
Washington, D.C. -- U.S. Energy Secretary Samuel Bodman and Agriculture Secretary Mike Johanns today announced that the Department of Energy and the Department of Agriculture have jointly selected 11 projects for awards totaling $8.3 million for biobased fuels research that will accelerate the development of alternative fuel resources.... These research projects build upon DOEs strategic investm...Departure to cold water corals and other 'hot spots'
... Bremerhaven, 24 May 2007. With a new coat of paint, thorough ship inspection, and sailing under the flag of the Helmholtz Association, Polarstern begins to make its way toward the north on May 29. The flagship of the Alfred Wegener Institute for Polar and Marine Research (AWI), is initially heading to Northern Norway and then on to Spitsbergen during its 22nd Arctic expedition. One of the s...Analysis reveals extent of DNA repair army
Cells have the remarkable ability to keep track of their genetic contents and -- when things go wrong to step in and repair the damage before cancer or another life-threatening condition develops.... But precisely how cells monitor the integrity of their genomes, identify problems, and intervene to repair broken or miscoded DNA has been one of nature's closely held secrets. Now, however, a rep...Nanotechnology requires immediate changes in EPA
WASHINGTON Regulatory oversight of nanotechnology is urgently needed and the Environmental Protection Agency (EPA) should act now, reports a new study released today. In EPA and Nanotechnology: Oversight for the 21st Century, former EPA assistant administrator for policy, planning and evaluation, J. Clarence (Terry) Davies, provides a roadmap for a new EPA to better handle the challenges of nano...Repair of DNA by Brca2 gene prevents medulloblastoma
... The St. Jude researchers demonstrated that the Brca2 gene plays a dual role in the developing nervous system, eliminating errors in the DNA of newly made copies of chromosomes and suppressing the onset of the brain cancer medulloblastoma. Medulloblastoma is a cancer of the cerebellumthe lower back part of the brain that cont...EPA and nanotechnology: Oversight for the 21st century
... A new report by J. Clarence (Terry) Davies, EPA and Nanotechnology: Oversight for the 21st Century, examines the EPA role in nanotechnology ov...... Kunio Satou and Hiroshi Nishiura analysed blood test data from 2,500 pigs, natural hosts for the virus, on Japanese farms at Hokkaido, Honshu and Kyushu....DNA repair proteins monitored at double-strand break
... Using a technique developed specifically for this project, the St. Jude researchers could determine when repair proteins arrived at or around the DNA break and evaluate its repaireven when particular proteins shifted away from the break to make room for others. A...Gladstone's Deepak Srivastava receives E. Mead Johnson Award for achievement in pediatrics
... Dr. Srivastava was honored for his work in discovering the intricate networks that regulate normal and abnormal cardiogenesis, along with his contributions in understanding the ge...Adult stem/progenitor cells repair of damaged brain, pancreas, kidney cells newly understood
... The cells not only differentiate to replace injured cells, as had been understood, but they also stimulate the proliferation and differentiation of stem cells already present in the injured tissue and they transfer mitochondrial DNA to local cells in which the mitochondri...Protein found that slows hepatitis C growth in liver cells
... The anti-hepatitis C activity of the protein, called p21-activated kinase 1 (PAK1), was discovered by scientists at the University of Texas Medical Branch at Galveston (UTMB), who describe their findings in an article in the current issue of the Journal of Biological Chemistry. In addition to presenting the researchers discovery that PAK1 controls the rate at which hepati...Study shows food preparation may play a bigger role in chronic disease than was previously thought
... This class of toxins, called advanced glycation end products (AGEs), are absorbed into the body through the consumption of grilled, fried, or broiled animal products, such as meats and cheeses. AGEs, which are also produced when food products are sterilized and pasteurized, have been linked to inflammation, insulin resistance, diabetes, vascul...Story tips from the Department of Energy's Oak Ridge National Laboratory, April 2007
... Increased levels of ozone associated with the release of greenhouse gases are causing vegetation to use more water and may intensify the effects of global warming on ecological systems, according to findings published in New Phytologist. Researchers Sandy McLaughlin of the University of Tennessee and Stan Wullschleger of Oak Ridge National Laboratory conducted studies of trees in the mounta...Study links faulty DNA repair to Huntington's disease onset
... ... The s...EPA selects Phylonix to screen compound library in zebrafish
Cambridge, MA April 12, 2007 -- Phylonix Pharmaceuticals, Inc. today announced it has been awarded a major, two-year contract for up to $4.3 million by the Environmental Protection Agency (EPA) as part of the agencys ToxCast project to correlate compounds having known toxicities with biological activities in a zebrafish test system. ... "We are very pleased that the EPA has chosen Phylonix to...2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things. However, individuals with just a single mutant copy of one of these genes are also at increased risk of developing cancer. This occurs when the remaining "g...3 proteins may play important role in nerve-cell repair
... ... ... "Our findings suggest th...Story tips from the Department of Energy's Oak Ridge National Laboratory, March 2007
... A new material developed at Oak Ridge National Laboratory's Nanoscience Center could replace a costly process in the manufacture of biodiesel that consumes chemicals, water and energy and also reduces the yield of the final product. During production, catalysts must be applied to transform biodiesel from a thick and sticky substance into a fluid form that can easily be pumped into vehicles....