Amgen investigational therapy, AMG 162, increased bone mineral density with twice yearly injection
...e resorption. Amgen scientists have confirmed the essential role of RANK Ligand pathway in the formation, activation and survival of osteoclasts, the cells that are associated with bone resorption. RANK Ligand is responsible for osteoclast-mediated bone loss in a range of conditions including osteoporosis, tr...Columbia University scientist wins 2004 Nobel Prize
...ted by rotting fish. The sense of smell is essential to the survival of most species, who use their olfactory systems to identify food, smell predators and observe and interpret their environments. In humans, smells warn us if food has gone bad and can be powerful enough to trigger distinct memories y...Dying cells encourage neighbors to grow
...unding cells. "Such compensatory mechanisms may be essential to allow for the elimination of as many damaged or dangerous cells as needed without compromising organismal fitness. In spite of its importance, the underlying mechanisms are poorly understood," explains study leader Dr. Hermann Steller. Dr. Stel...Protein energy profiles offer clues about amyloids
...t. "By designing simplified models that retain the essential physical and chemical features of protein dynamics, Clementi's team is making excellent progress in quantitative prediction -- work that's highly complimentary to the detailed simulations we're creating through Folding@Home." Basic thermodynamics dic...New biosensor rapidly detects deadly foodborne pathogen
...bility to detect L. monocytogenes at low levels is essential because most of the foods susceptible to Listeria contamination are ready-to-eat products, which are cooked or otherwise processed for human consumption before they make it to a grocer's shelves. "Since precooked meats have already bee...September/October 2004 Annals of Family Medicine tip sheet
...ing part in primary care research, are emerging as essential laboratories for the generation of new knowledge relevant to the types of problems and patients seen in primary care. This expanded issue of Annals of Family Medicine features nine studies from PBRNs. From an original research study examining the pot...Biologists ID molecular block for social 'cheaters'
...lies on-- tying cooperative genes tightly with the essential function of reproduction," said paper co-author Jo...pores. "This test confirmed that the dimA gene was essential not only for DIF-1 recognition but also for spore production," said paper co-author Gad Shaulsky, as......he development of Grid computing, which will be an essential element of the LHC, CERN's new particle accelerato...e and in the culture of CERN. Sharing knowledge is essential for a centre of excellence in particle physics, with a mandate to make its results freely available....Component of volcanic gas may have played a significant role in the origins of life on Earth
...t the chemistry necessary for life, and formed the essential physical structures of life (something done primarily by proteins today). But how did that RNA world come about? "Anybody who thinks they know the solution to this problem [of the origin of life] is deluded," says Orgel. "But," he ad...UCR researchers identify key plant enzyme that defends against multiple infections
...s, or enzymes that degrade proteins, which play an essential role in initiating and carrying out programmed cell death in animals. Caspase-like activities have also been shown to be required for the initiation of programmed cell death in plants, but the genes controlling those activities have not been identif...Report: How 10 top new technologies will help world reach globally-agreed goals by 2015
...ould give developing countries access to knowledge essential to their reaping the benefits of genomics for development. It would promote actions needed at a global level, strengthen capacity in biotechnology worldwide by increasing the international exchange of know-how, and encourage partnerships between cou...Emory chemists develop bacteria that may help decaffeinate coffee
...ch." In bacteria, riboswitches normally recognize essential molecules, such as vitamin B12, and switch the production of proteins on or off. The Emory team created a synthetic riboswitch that recognizes theophylline, and turns on the production of a protein known as "cat" which allows the cells to survive in ...FSU scientist links iron imbalance to Parkinson's disease
...il further studies determine optimal levels of the essential nutrient, Levenson advises health-conscious consumers without doctors' orders to forego the mineral in tablet form in favor of natural dietary sources like red meats, dried fruits, dark leafy greens, tofu, cooked dried beans or wheat germ. "I'...Mitochondria findings may help beat wide range of disease
...ay in both normal and aberrant cell biology, it is essential to first understand the fusion-fission process tha...tential to reveal keen insights into the basic and essential cell-mitochondria relationship, leading to increased understanding of the aging process; and potenti...Time-lapse movies show brain cells move like a two-stroke engine
...which had been controversial. Although the cage is essential for the cell to migrate, further experiments showed that it does not initiate cell movement. Comparing the elements of the cage in migrating and stationary cells, the researchers found no difference. Next the researchers looked at the protein Par6-a...Amphibians in dramatic decline; Up to 122 extinct since 1980
...e distribution of each species, and gathered other essential ecological information. ...Researchers find protein that makes long-term memory possible
...tually takes place in the brain, and that mBDNF is essential to the long-term memory process," said Dr. Pang. ...ew proteins from being made. Protein synthesis is essential for the formation of long-term memory and, before the current study, researchers had searched for ye...Using fruitflies to examine alcohol tolerance
...ely studied organisms in biology, and has provided essential insights into developmental and cellular processes that are shared with higher animals, including humans," said Berger. "Flies have a relatively sophisticated nervous system and are capable of many well-characterized complex behaviors, including res...Purdue chemists give an old laboratory 'bloodhound' a sharper nose
...osition of unknown substances. Mass spectrometers, essential tools in any modern chemistry lab, are often used by law enforcement to test suspicious-looking residues that could indicate the presence of explosives or drugs inside packages. But while most mass spectrometers are unwieldy, cabinet-sized machines t...... required for Dpp morphogen movement, albeit it is essential for its signaling activity. ...