Tag: "estrogen" at biology news

Good news: As you age, leg blood vessels adapt so you can still exercise without fainting

...e conducting similar experiments in women (both on estrogen replacement and not). They plan to study the mechanisms underlying age-related changes in vascular responsiveness to sympathetic stimulation; and to examine the importance of sympathetic outflow in regulating vascular tone and oxygen delivery to exe...

Estrogen protects male rats from aortic aneurysms

... "Earlier studies have demonstrated that increased estrogen systemically inhibits the development of AAAs," Up...rch and his research team implanted a slow-release estrogen pellet in half the male rats, while the other half went through the same implantation procedure, but...

Combination hormone therapy doubles breast density and quadruples risk of abnormal mammograms

...n, ages 50 to 79, who were participants in the WHI estrogen plus progestin trial, which involved more than 16,...in the sub-study were randomly selected to receive estrogen plus progestin and half received an identical-looking placebo. All received a baseline mammogram at ...

Hormone therapy's effect on breast density is not the same for all women, Group Health study finds

...discovered that hormone therapy (HT), specifically estrogen plus progesterone therapy, increases breast densit...s association was strongest among current users of estrogen plus progestin (vs. estrogen only). "Recent research on hormone therapy has raised lots of questio...

High fiber intake reduces estrogen levels in Latina women, according to researchers

...dietary fiber is associated with lower circulating estrogen levels. Because high estrogen levels have been linked to breast cancer, this finding could provide a significant step toward preve...

Study demonstrates Cenestin reduces sleep disturbances/night sweats in post-menopausal women

...ti shows that a plant-derived synthetic conjugated estrogen called Cenestin (synthetic conjugated estrogens, A...and sleeping for a longer period of time. "When estrogen levels in a woman's body decrease, their difficulties with sleep increase," said Dr. Scharf, whose d...

Red wine mist? Resveratrol shows potential effects against COPD, asthma, arthritis

...archers showed that "resveratrol did not act as an estrogen or glucocorticosteroid," each of which have patien...y agents. Their mechanism of action is not via the estrogen or glucocorticoid receptor; thus these agents might be beneficial in inflammatory diseases where glu...

Army-funded effort examines androgen's role in bone loss

...ls. Androgen testosterone is best-known type and estrogen both contribute to adult bone mass maintenance: An...anabolic agent that stimulates bone formation, and estrogen is thought to have a protective effect on bone by inhibiting resorption. "In osteoporosis, you...

New breast cancer study shows hormonal therapy not enough

...men with hormone-dependent breast cancer (requires estrogen and/or progesterone to grow) may be undertreated i..."We discovered that women with very high levels of estrogen receptor in their tumors can probably avoid chemotherapy, but those with lower or intermediate level...

The Molecular Profiling Institute named US provider of genetic breast cancer test

...h node negative with either a positive or negative estrogen receptor status. Taken together with a patient's c...y, oncologists use several clinical factors --age, estrogen receptor status, tumor size and grade-- to determine how a patient's tumor will behave and how best ...

Component of plastic stimulates growth of certain prostate cancer cells

...industrial chemical and nonsteroidal environmental estrogen used in the manufacture of food cans, milk container linings, food storage containers and water supply pipes. About 2.5 billion pounds of the chemical are produced each year. In particular, the study showed that the affected class of prostate cancer ...

Genetic polymorphisms, antidepressant use may be associated with altered tamoxifen activity

...creasing importance as therapeutic alternatives to estrogen for the treatment of hot flashes in patients with breast cancer as well as in unaffected women, in addition to their already established role in treatment of depression and other psychiatric illnesses. It is possible that testing of CYP2D6 genetic va...

EB and IUPS - Where cures of tomorrow can be seen in the science of today

... cardiovascular disease; genetic susceptibility to estrogen carcinogenesis; and long term effects on adolescents' developing brains of nicotine, stimulants and other drugs. Other sessions focus on the effect of social structure and influences on drug actions and discuss how pharmacologists and other scientis...

Study provides insights on why some prostate cancer becomes resistant to hormone withdrawl therapy

...ecome cancer-causing genes known as oncogenes. The estrogen and progesterone receptors--two receptors that become defective in many breast cancers--are also members of this protein family. The androgen receptor is a protein produced by prostate cells that binds to androgens, a family of chemically related hor...

Increased risk of osteoporosis associated with gene that one in five people have

... women the variant gene speeds up the breakdown of estrogen and is associated with low density in the bones of...detoxifies foreign substances and also breaks down estrogen as a normal part of maintaining proper estrogen balance. Within the general population, several vari...

Controlling protein diversity

... have shown in previous studies that hormones like estrogen and progesterone can change the amounts of proteins made by their target genes. When hormone binds to receptors inside the cells, they are activated to seek out target genes. They then recruit the coactivators in this case CAPER and CAPER. These coa...

Research focusing on why estrogenic hormones produce differing results

... right now for women to make a choice about taking estrogen or other estrogen-like compounds, and, I think, it...o the argument that the long-held model for how an estrogen receptor binds to DNA and, in turn, regulates gene transcription is need of retooling. Nardulli's te...

Findings suggests that blocking estrogen may be crucial to lung cancer survival

... may rest on their ability to hinder the action of estrogen in lung cancer cells, according to two studies pub...n current knowledge about the relationship between estrogen and lung cancer growth and suggest that blocking estrogen may be vitally important to improving surv...

Signaling protein builds bigger, better bones in mice

...otected from the usual loss of bone density due to estrogen deficiency," MacDougald adds. To confirm that Wnt10b was the key to increased bone formation, Bennett and Hankenson scanned bones from a strain of laboratory mice that didn't have a gene for Wnt10b. Lacking the ability to produce Wnt10b protein in bo...

What are little boys made of?

...ts on mice, the researchers found evidence that an estrogen receptor in the hypothalamus called ER reg...) produced by their testes. Estradiol binds to the estrogen receptor (ER) and this acts to turn on, or turn off, other genes which sculpt the neural arc...

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(Date:10/15/2014)... the 44th Rosenstiel Award for Distinguished Work in Biomedical ... the mechanisms of genomic instability and its implications for ... second alumnus to win the Rosenstiel Award; the first, ... Alt is the Charles A. Janeway Professor of Pediatrics ... an investigator at the Howard Hughes Medical Institute at ...
(Date:10/14/2014)... – Scientists have sequenced the house fly genome for ... might expect from an insect that thrives in pathogen-rich ... Oct. 14 in the journal Genome Biology , ... and of how flies quickly adapt to resist insecticides, ... house flies (Musca domestica) carry and transmit more than ...
(Date:10/14/2014)... of scientists led by researchers at the University ... of Miami Miller School of Medicine (UMMSM) have ... underlying bipolar (manic depressive) disorder, a breakthrough that ... affective disorder, as well as depression and other ... online this week in Nature Molecular Psychiatry ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2House fly genome reveals expanded immune system 2Rare genetic disease protects against bipolar disorder 2Rare genetic disease protects against bipolar disorder 3
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