Geisinger scientist seeks cure for Lou Gehrig's disease, creating device to find treatment
... ... Lou Gehrig's disease-or ALS or amyotrophi...$5M gift will attack Lou Gehrig's disease from all angles
... ... Now, he has greatly increased that support, with a new $5 million gift, and the promise of even further funding...Researchers discover misfolded protein clumps common to dementia, Lou Gehrig's disease
... Virginia Lee, Ph.D., and John Trojanowski, M.D., Ph.D., of the University of Pennsylvania, led an international team of scientists in this discovery. The work was...Exercise plus gene therapy shows promise for treating Lou Gehrig's disease
COLUMBUS, Ohio A new study in mice gives hope that a combination of gene therapy and exercise may extend the lives of people who have Lou Gehrig's disease.... ...Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a chronic and progressive illness that leads to paralysis and ultimately death. There are no known cures, and the only FDA-approved method for treating the disease is a dr...Protein aggregates in Lou Gehrig's disease linked to neuron death
EVANSTON, Ill. --- French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis (ALS) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure. ... ...What is known about Lou Gehrig's disease, as it is commonly called, is that misfolded and damaged proteins clump together in cells to form aggr...Bethesda, MD A new study indicates that mutant Cu/Zn superoxide dismutase (SOD1) enzymes that are associated with an inherited form of Lou Gehrig's disease cause the protein to become sticky in tissues. Partial unfolding of the mutant protein can expose hydrophobic residues that may promote abnormal interactions with other proteins or membranes in the cell. ...... The research appears as the "Pa...