Gladstone's Deepak Srivastava receives E. Mead Johnson Award for achievement in pediatrics
... Dr. Srivastava was honored for his work in discovering the intricate networks that regulate normal and abnormal cardiogenesis, along with his contributions in understanding the ge...Gladstone scientists identify critical gene factor in heart development
SAN FRANCISCO, CA -March 29, 2007 -- Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) announced they have identified a critical genetic factor in the control of many aspects of heart form and function. As reported in the journal Cell, scientists in the lab of Deepak Srivastava, MD, have successfully deleted a genetic factor, called a microRNA, in animal models to understan...Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco. ...... Using a unique mouse model, Gladstone Investigator Yadong Huang, MD, PhD, and his team have proven that, under certain conditions, neurons produce Alzheimer's-linked apolipoprotein E.... ... Also known as apoE, this...Gladstone Institutes receives funding for training grant from stem cell institute
The California Institute for Regenerative Medicine (CIRM) today announced that the J. David Gladstone Institutes and 15 other California nonprofit institutions have received the first year of funding for a three-year program designed to train the next generation of stem cell scientists. These are the first grants awarded by the California stem cell agency....... The Independent Citizens' Oversigh...Gladstone researchers hone in on differentiation of heart stem cells
A team of scientists from the Gladstone Institute of Cardiovascular Disease (GICD) has identified a key factor in heart development that could help advance gene therapy for treating cardiac disorders....... Published in the current online edition of the Proceedings of the National Academy of Sciences, the study evaluates the role of short RNAs, also known as miRNAs, in the early stages of the dev...Gladstone study links Alzheimer's with toxic protein fragments
New research from the Gladstone Institute of Neurological Disease details exactly how a mutant form of the protein apolipoprotein E, also known as apoE, is a causative factor for Alzheimer's disease....... It pinpoints mitochondria, the organelles within cells designed to turn glucose into energy, as a key site that specific fragments of a particular form of apoE attack, leading to the neuronal d...Gladstone researchers identify new drug target for Alzheimer's disease
San Francisco, Calif. (December 1, 2005)--Researchers at the Gladstone Institute of Neurological Disease have identified a potential new way to stop brain cell death related to Alzheimer's disease. ... ...Working with cell cultures, the scientists investigated how amyloid beta proteins, which build up in the brain tissue of people with Alzheimer's disease, kill neurons. The cell cultures were est...Gladstone Institutes assists with Exploratorium stem cell exhibit
Members of the Gladstone Institutes' Conklin lab and Embryonic Stem Cell Lab provided living cells and helped train museum staff members for the development and launch of a current Exploratorium exhibit featuring live mouse embryonic stem cells. ......The interactive exhibit opened to the public on July 1 and continues through January 8, 2006. Located in the Exploratorium's high-resolution Micr...CIRM awards $2.4 million training grant to the Gladstone Institutes
The California Institute for Regenerative Medicine (CIRM) has awarded the J. David Gladstone Institutes a $2.4 million grant to create a CIRM Scholars Training Program focusing on stem cell research. The training grant, part of CIRM's first-ever round of awards, enables Gladstone to develop and implement an intensive stem cell-specific curriculum for ten postdoctoral fellows over a three-year per...Gladstone investigators discover how resting T cells avoid HIV infection
Scientists have discovered the mechanism that enables some CD4 T cells -- the main target of HIV -- to thwart the virus. The discovery, reported on April 13 in the online version of Nature, could open the door to an entirely new strategy for preventing the spread of HIV infection in the body's cells, according to the senior author of the study, Gladstone Institute of Virology and Immunology Direc...Gladstone investigator Steve Finkbeiner wins prestigious Lieberman Award
The Hereditary Disease Foundation has named Steven Finkbeiner, MD, PhD, an assistant investigator at the Gladstone Institute of Neurological Disease and assistant professor of neurology and physiology at University of California, San Francisco (UCSF), as the recipient of its highly esteemed Lieberman Award. ......The annual honor, featuring $150,000 in research funding over two years, is designed...Gladstone building honored with San Francisco Business Times award
The new J. David Gladstone Institutes research facility, located at Mission Bay in San Francisco and dedicated in December, is the recipient of the San Francisco Business Times 2004 Real Estate Deal of the Year Award as Best New Office R&D Development/San Francisco. The honor is announced in a special section of the Business Times current (March 25-31) issue. ......"We are delighted to receive th...Gladstone scientists announce new version of bioinformatics software program
A team of scientists at the J. David Gladstone Institutes has unveiled a new version of GenMAPP, a widely used software program designed to help biomedical scientists view and analyze genome-scale data sets in the context of biological pathways. ......GenMAPP 2.0, short for Gene Map Annotator and Pathway Profiler, marks the first major revision of the program, which was developed and launched by...Gladstone researchers resolve key Huntington's disease mystery in Nature cover story
A mystery long associated with Huntington's disease has been resolved by a team of researchers at the UCSF-affiliated Gladstone Institute of Neurological Disease, thanks to a specially designed microscope that allows researchers to track changes in cells, including those associated with neurodegeneration, over long lengths of time.... ...As reported in the cover story in the current issue of Natu...