Studying the chemistry of drugs in wastewater
...which significant wastewater treatment occurs) and identified the resulting products using multiple techniques. Scientists found that the reactions are complicated and often produce several products, some unexpected. For instance, acetaminophen forms multiple products, two of which are highly toxic. All the dru...DNA sequence controls expression of gene involved in cancer
... the ARE. From these constructs, the investigators identified a region of 30 nucleotides outside the ARE that destabilizes bcl-2 mRNA both in the absence and in the presence of the ARE. Because the region is composed mostly of cytosine and adenine repeats, they named it the CA-repeated Region (CAR). The discov...Endangered frogs coexist with fungus once thought fatal
...8, the fungus Batrachochytrium dendrobatidis was identified from sick and dead frogs and, since then, several lines of laboratory based evidence have suggested that B. dendrobatidis is to blame for the dramatic frog declines. But with little information about how the disease impacts frogs in the wild, the c...Columbia University scientist wins 2004 Nobel Prize
...molecular biology to problems in neurobiology. He identified the peptide genes responsible for eliciting an innate behavior in a marine snail, and molecular analysis of these genes suggests how diverse behavioral patterns may be encoded in the genetic material and inherited from parent to offspring. ...HHMI researchers Richard Axel and Linda Buck win 2004 Nobel Prize
...ns, mice, catfish, dogs, and salamanders have been identified in this way. The team's most surprising finding wa...receptors. The 100 different genes the researchers identified first were just the tip of the iceberg. It now appears that there are between 500 and 1,000 separate...Daphne Koller named MacArthur Fellow
...l to identifying modules of co-regulated genes and identified regulatory roles for several proteins whose functions had been previously uncharacterized. Koller received her bachelor's (1985) and master's (1986) degrees from the Hebrew University of Jerusalem, followed by a doctorate (1993) from Stanford....Below the surface: New clues to plant signaling from the roots
... authors show that it is different from previously identified plant hormones or signaling molecules and report evidence that it may be a novel carotenoid. ...Marine Biological Laboratory summer investigator wins Nobel Prize in Chemistry
...with Joan Ruderman of Harvard University, he later identified a specific ubiquitin ligating complex that "targets cyclin B for degradation at the end of mitosis"-the final phase of cell division. Today Hershko is studying that ubiquitin ligating complex in both clam eggs and cultured human cells in hopes ...Brain circuit may permit scientists to eavesdrop on memory formation
Howard Hughes Medical Institute researchers have identified a circuit in the brain that appears crucial in converting short-term memories into long-term memories. The circuit links the major learning-related area of the brain to another region that governs the brain's higher functions. The studies open the wa...Botulism bug says no to nitric oxide, provides key to molecule's role in human cell signaling
...the evolutionary development of the sensor protein identified in C. botulinum, dubbed SONO for "sensor of NO," the scientists were able to determine the three-dimensional structure of a related nitric oxide sensor in a different bacterium. That structure will provide a key to unlock answers to some questi...UCR researchers identify key plant enzyme that defends against multiple infections
... from the University of California, Riverside have identified one of the key enzymes that trigger programmed cell death, an important process plants undergo in fighting off bacterial, fungal or viral infections. The development holds out hope of improving crop yields, which are dependent on plants being able to...New risks for bladder cancer identified by MIT team
...BRIDGE, Mass.--MIT researchers and colleagues have identified three new chemical risk factors for bladder cancer...nt cancer rather than treat it." The team also identified six chemicals in the same chemical family that do not appear to be human carcinogens. Because they a...US Agency for International Development awards $34 million to Virginia Tech
...verty and pollution. For example: IPM research has identified key pests in Uganda (coffee wilt pathogen), Philippines (onion root knot nematode), Mali and Bangladesh (tomato leaf curl geminiviruses), the Caribbean (pepper gall midge), and Central America (snow pea leafminer). At one site in the Philippines, tho...Embryonic stem cells correct congenital heart defect in mouse embryos
...and the molecular basis of the rescue, the authors identified two important molecules implicated in signaling from the ES cells to the Id knock-out cells. These molecules are insulin-like growth factor 1 (IGF-I) and WNT5a. The former molecule is a long-range acting factor, and the latter is a short-range factor...Acoustics meeting in San Diego
...ho suffer from the disorder. Previous studies have identified components of words (such as stressed syllables) and even parts of sentences that are more likely to trigger stuttering episodes, but the reasons for why this happens remain unclear. In efforts to pinpoint the causes even more precisely, Timothy Arb...Rutgers-led research offers new clues in the genetic mysteries of maize
... as much as 22 percent of the maize genes could be identified as being different. This was surprising, considering that other close relatives such as chimpanzees and humans differ in less than one percent of their genes. "It looks like significant evolutionary change happened in a relatively short time," sa...Study in Royal Society journals presents evidence for inherited factors in homosexuality
...edi, Dr. S Rodriguez-Zas and Dr KA Hughes We have identified several genes associated with variation in male re...on level of over 14,000 genes in the fruit fly and identified 27 that were strongly associated with differences in male reproductive success. One of these genes i...UNC scientists identify sticky protein in sickle cell red blood cells
...to blocked blood vessels, the signaling mechanisms identified in sickle reticulocytes seem to be present in reti...nd not just sickle cell disease"The UNC study also identified where Alpha-4Beta-1 binds to thrombospondin. "This knowledge opens the door to possib...Channel protein converts vibrations to electrical signal
Researchers have identified a molecule that can transform the mechanical stimu...nsory in the fruit fly a molecule known as NOMPC, identified by HHMI investigator Charles S. Zuker. In other parts of the nervous system, however, the TRPA1 chan...Experimental drug prevents vaginal simian HIV transmission in monkeys Science study says
... are urgently needed, the authors write. "We have identified a key target for strategies to prevent vaginal HIV transmission and have a candidate molecule that blocks this target," said Science author Michael Lederman from Case Western Reserve University in Cleveland, Ohio. "There is a real need for a topica...