JCI table of contents: January 25, 2006
... Multiple sclerosis (MS) is a chronic inflammatory disorder that causes degeneration of the nerves in the brain and spinal cord, leading to various symptoms including muscle weakness and pain. Most individuals with MS go through cycles of disease and remission, leading to the suggestion that there are regulatory mechanisms that counter the disease-causing inflammation. Using a mouse model of...ACS News Service Weekly PressPac -- January 24, 2007
... ... ... ... In This Edition:... ... Toward development of...Story tips from the Department of Energy's Oak Ridge National Laboratory, January 2007
... ORNL researchers performing basic research have discovered a carbon nanotube-based system that functions like an atom-scale switch. Their approach is to perform first-principles calculations on positioning a molecule inside a carbon nanotube to affect the electronic current flowing across it. The result is an electrical gate at the molecular level: In one position, the molecular gate is open...ACS News Service Weekly PressPac -- January 10, 2007
...... ...Weekly PressPac - Jan. 10, 2007 ...ALL CONTENT IS FOR IMMEDIATE USE EXCEPT ARTICLE #5 (EMBARGOED FOR 9 A.M., EASTERN TIME, JAN. 15, 2007) ...... ... The American Chemical Society (ACS) News Service PressPac is your access p...JCI table of contents -- January 11, 2006
... In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity. Most studies have focused on understanding the defects in T cell activation caused by the WASp deficiency, but researchers at the University of Washington in Seattle have now found that in mice and humans a population of T cells known as regulatory T cells (Treg)...Highlights from the January 2007 Journal of the American Dietetic Association
... ... Watching television, eating family meals and the safety of the neighborhood all play a role in children's weight, according to researchers at the University of Missouri....Other highlights in the January 3 JNCI
...Regular use of cholesterol-lowering drugs called statins is not associated with a reduced risk of colorectal cancer, according to a population-based case-control study. ... Laboratory tests of statins have found anticancer effects on colon cancer cells. One case-control study of people found that use of statins for at least 5 years reduced the risk of colorectal cancer by 50 percent. To furt...JCI table of contents: January 2, 2007
... ... The group of drugs known as beta blockers help slow nerve impulses traveling through the heart in order to reduce the heart's workload. This effect is achieved via their action on beta-adrenergic receptors present in cardiac cells. As such, beta blockers have become a mainstay of the treatment regimen for chronic heart failure. However, doctors have remained puzzled by the variable res...Other highlights in the January 18 JNCI
... Women infected with HIV types 1 and 2 may have a higher risk of HSIL than HIV-negative women, according to a new study in Senegalese women....... Stephen E. Hawes, Ph.D., of the University of Washington in Seattle, and colleagues studied a cohort of 627 women with and without HIV types 1 and/or 2 and/or high-risk human papillomavirus (HPV) infection in Senegal, West Africa. They followed th...JCI table of contents: January 12, 2006
......Blockade of fat hormone helps halt and heal multiple sclerosis ... ...Italian researchers have found that blockade of the hormone leptin, which is primarily produced in fats cells, has beneficial effects on the induction and progression of experimental autoimmune encephalomyelitis (EAE) in mice the animal model of human multiple sclerosis (MS). In their study appearing online on January 1...JCI table of contents: January 4, 2006
... ... Soy diet worsens heart disease ... ...Researchers from the University of Colorado have shown that mice carrying a genetic mutation that is linked to altered heart growth and function in humans, have significantly worse heart problems if fed a soy diet, when compared to mice fed a soy-free (milk proteinbased) diet. This is the first study to provide evidence that an environmental influenc...Other highlights in the January 4 JNCI
... A new study has found that a cancer drug and an engineered form of the herpes simplex virus may work together more effectively than either agent alone to destroy glioblastoma cells from human brain cancers....... The drug temozolomide, which stops tumor growth by preventing DNA replication in the cell, was approved in 2005 for the treatment of glioblastoma, a rapidly fatal type of brain canc...Story tips from the Department of Energy's Oak Ridge National Laboratory, January 2005
FORENSICS The telltale tree . . . ... ...Logs confiscated by police at a Texas murder scene and the work of a scientist at Oak Ridge National Laboratory may help put a killer behind bars. Using a technique called laser-induced breakdown spectroscopy, Madhavi Martin obtained "chemical fingerprints" from a partially burned log at the crime scene and compared them to those of logs that had been p...Other highlights in the January 5 JNCI
...... A new study has found that blocking vascular endothelial growth factor receptor 3 (VEGFR-3) prevented lymphangiogenesis in a mouse model but had no effect on blood angiogenesis or the survival or function of existing lymphatic vessels. Specifically targeting VEGFR-3 may inhibit tumor metastasis by preventing lymphatic vessel growth by the tumor, the study concludes....... VEGFR-3 plays an...JCI table of contents, 3 January 2005
Cincinnati study of Chernobyl residents uncovers new cause of thyroid cancer ... ...Cincinnati University scientists studying papillary thyroid cancer in Chernobyl residents following the 1986 nuclear plant accident have identified a novel genetic mutation event that occurs as a result of their exposure to high levels of radioiodide.... ...Yuri E. Nukiforov led a team of researchers from bot...Highlights of January 2005 issue of Biology of Reproduction
The January 2005 issue of Biology of Reproduction marks the start of the co-editorship of Drs. John Eppig and Mary Ann Handel. The new editors-in-chief, along with members of their board of associate editors, will provide highlights of some of the prominent papers in each issue of the journal. Following are the January highlights of groundbreaking papers dealing with genetic modification of germl...Highlights of January Journal of the American Dietetic Association
The January 2005 issue of the Journal of the American Dietetic Association contains articles and research studies you may find of interest. Below is a summary of some of this month's articles. For more information or to receive a faxed copy of a Journal article, e-mail . ...... ...Coffee gets its perk from caffeine, and so do soft drinks and tea. According to researchers from the University of V...