NIH awards new $14.5 million, five-year grant to the Scripps Research Institute
...boratory, in collaboration with Benjamin Cravatt's laboratory at Scripps Research, published in Science the crystal structure of the integral membrane protein fatty acid amide hydrolase at 2.8A resolution. Fatty acid amide hydrolase degrades endocannabinoids, molecules involved in pain signaling, and is a curr...Studying the chemistry of drugs in wastewater
...titute of Standards and Technology (NIST) is using laboratory experiments to help answer this question by studying what happens to pharmaceuticals when they react with chlorine--a disinfectant commonly used in wastewater treatment. Scientists around the world often find drugs in water samples taken from streams...New therapy for specific form of leukemia
...Cools has already successfully conducted the first laboratory tests with Glivec on the cancer cells of these patients. Ingenious research The team of Jan Cools and Peter Marynen, along with Carlos Graux and colleagues from the Centre for Human Heredity under the direction of Anne Hagemeijer, noticed that the ...Endangered frogs coexist with fungus once thought fatal
...k and dead frogs and, since then, several lines of laboratory based evidence have suggested that B. dendrobatidis is to blame for the dramatic frog declines. But with little information about how the disease impacts frogs in the wild, the causal role of this chytrid fungus remains unclear. In the open access ...How roots control plant shoots
...becca Frederick, who formerly worked in Sieburth's laboratory and now is a graduate student in biochemistry. Seeking the Secrets of How Leaves Grow Sieburth's research focuses on a seemingly simple question: "How do leaves grow? It's a basic biological question," she says. Plants look different dependin...Mayo Clinic awarded major NIH contract for smallpox genomics research
...y the Mayo Genotyping Share Resource (GSR), a core laboratory under the direction of co-investigator Julie Cunningham, Ph.D. Other aspects of the research including bioinformatics -- the processing of the huge number of data points in this type of genomic research -- will involve Mayo biostatisticians and the ...Good news: As you age, leg blood vessels adapt so you can still exercise without fainting
...ith age. Proctor noted that his laboratory group "is one of the first to systematically study the impact of aging on blood flow to exercising muscle in healthy humans." It's important to study how healthy people age, he noted, "because keeping our rapidly expanding older population healthy w...September/October 2004 Annals of Family Medicine tip sheet
...ce and applicability to primary care patients than laboratory studies, it does have its challenges. The authors use a case study to discuss several challenges associated with psychosocial intervention research in community-based primary care. The authors posit several criteria, which may help shape future resea...NIH awards Emory and Georgia Tech $10 million for partnerships in cancer nanotechnology
...rt of the process to move this technology from the laboratory to the bedside in the fight against cancer." ...h environment to transform nanotechnology from the laboratory into promising diagnostics and therapies for cancer patients." The Bioengineering Research Partnersh...After flu exposure, mild exercise protects mature mice from dying
...t of flu-specific immune cells. At the moment, the laboratory also has a large NIH-funded human clinical trial underway examining whether or not moderate exercise training can improve immunological vigor --including responses to influenza vaccine -- in older adults....U-M scientists see ubiquitin-modified proteins in living cells
...icular partner." Scientists in Kerppola's laboratory have used bimolecular fluorescence complementation methods to study protein interactions and signaling pathways, in addition to ubiquitination. While the technology should be generally applicable to most interactions, it does have some limitations. ...Sedentary overweight people get insulin boost from short term exercise; CVD risks trend down
...undergraduate honors student), both working in the laboratory of Barry Braun in the Department of Exercise Science, University of Massachusetts, Amherst. Black will present, "Improved insulin action following short-term exercise training: effects of exercise or energy balance?" while Mitchell will present "The ...Study describes basic mechanism in cell growth control involving damaged DNA
...hor, added that a major goal of his UNC Lineberger laboratory is to understand the molecular mechanisms controll...nt, is key to controlling cell division. Xiong's laboratory has been studying a family of enzymes called E3 ubiquitin ligases. These ligases place a long tail o...Why do African-American women have more pregnancy problems?
...peed the movement of research discoveries from the laboratory bench to the bedside. While compliance with traditional prenatal care among black women has improved in recent years, it still lags behind white women: 75 percent of black women seek prenatal care vs. 89 percent of white women. The discrepancy contin...Defense provides additional $4.9 million for pathogen research tool
...ing data sets. Through integration with VBI's core laboratory facility, VBI scientists and collaborators have access to a unique infrastructure for data generation, management, analysis, and dissemination. "The continuation of this project provides increased capabilities and infrastructure for our nation to mee...FSU scientist links iron imbalance to Parkinson's disease
...ere at the cellular level," said Levenson from her laboratory at FSU's Biomedical Research Facility. "Our primary research objective is to better understand how trace metal imbalances, which are associated with neuropsychiatric and neurodegenerative diseases, affect the molecular mechanisms that regulate gene e...New study on smallpox in monkeys reveals tactics of a killer
...llpox countermeasures. CDC has the only U.S. laboratory facility in which research using smallpox virus is permitted. However, many more labs in the United States have sufficient safety features for handling less-lethal pox viruses, such as monkeypox. If monkeypox--a pox virus less virulent in humans--pro...Estrogen protects male rats from aortic aneurysms
...r his study. Woodrum conducted his research in the laboratory of Gilbert Upchurch, M.D., an associate professor ...TVB paper describes how scientists in the Upchurch laboratory first perfused the aortas of male and female rats with elastase, an enzyme that triggers an uncontro...Study in Royal Society journals presents evidence for inherited factors in homosexuality
... have been observed in several different field and laboratory populations. These particular cycles are shown to ...eders are of similar size. We show in a controlled laboratory experiment that helpers reduce this risk of eviction by maintaining a 'safe size difference' with th......ponse was determined more than 20 years ago in the laboratory of HHMI investigator A. James Hudspeth but since that time, no one had been able to identify the channel protein. In the search for a molecule that might form the hair cell channel, the researchers turned to a family of ion channels known as TRPs, ...