Commandeering cellular machinery: recognition mechanism to detect small molecules
Researchers have learned how to commandeer the complex machinery that cells use to recognize and respond to such important molecules as steroid hormones, thyroid hormones and vitamin D. The development could provide a foundation for a new family of biologically-based mecha...Brain circuit may permit scientists to eavesdrop on memory formation
... the TA lesions in animals 24 hours after they had learned the position of the platform. These animals still retained short-term memory; but four weeks later they lost that memory as well. Since the lesion was made after learning, this experiment suggested that the animals had problems converting their short...Botulism bug says no to nitric oxide, provides key to molecule's role in human cell signaling
... part of a protective mechanism into a system that learned to use the toxin to benefit the organism." In human beings, nitric oxide binds to a receptor called soluble guanylyl cyclase to make cyclic GMP, a molecule that improves blood flow by relaxing blood vessel walls. Ferid Murad, M.D., Ph.D., profes...Society for Psychophysiology Research
...er the last eight years, 11 patients with ALS have learned to communicate directly to the computer by learnin...n-waves. Researchers have found that patients who learned to do this could then apply this skill to operate a computer program that allows patients to communi...Study describes basic mechanism in cell growth control involving damaged DNA
... altered during tumor development. Scientists have learned that the cell's ability to earmark proteins for recycling or degradation, often a target of cancer development, is key to controlling cell division. Xiong's laboratory has been studying a family of enzymes called E3 ubiquitin ligases. These ligases...Dr. Harris receives NIH Javits Neuroscience Investigator Award
...es change in size and number so information can be learned and remembered. "There have been a lot of people working hard together to develop the tools to investigate at the submicron level how the structure of the brain changes; we have to look at the submicron level because that is the size of synapse...To save dolphin's dorsal fin experts combine medical technology and teamwork
...xpert enlisted by Dolphin Quest. "The things we've learned working together to save Liko's dorsal fin will help other dolphins in the future and many, many other animals of all kind, as Liko's story helps introduce the concept of regenerative medicine to the veterinary field." The use of extracellular matrix...Molecule that helps DNA replicate may make good target for cancer therapy
...an invertebrate or a human. Therefore, whatever is learned from yeast--which are much easier to work with than are human cells--is likely applicable to humans, Bielinsky said. Among the next steps for her lab is to find exactly how Mcm10 interacts with the polymerase alpha complex, because disrupting this in...Mystery unwrapped: Texas A&M team uncovers mummy secrets
...s near the Suez Canal, Kennicutt and the team also learned that tar fueled fires in glass factories used by t...hat occurred about 2,000 years after the Egyptians learned the trick. "Another interesting thing we learned was that some of this tar used by the Egy...Evidence that learning is consolidated during sleep
...yzed brain activity in sleeping volunteers who had learned to navigate through a computer-generated virtual town have discovered evidence that spatial memories are consolidated during deep sleep. Also, the researchers say that they have shown for the first time that the activity level in the brain's learning...Gut microbes can open gates in fat cells
...ons of years of coevolution with us, microbes have learned to manipulate networks of human genes," Gordon says. "By defining these networks, we can learn 'new ways' to promote health." As a result of such research, physicians may one day opt to make specific changes in the mixture of a person's gut microorg...Do lead bullets continue to be a hazard after they land?
...said. However some lead escapes, he said. "But we learned that it is absorbed in the top few inches of soil and does not migrate beyond that," Rimstidt said. "Lead is not very mobile. It does not wash away in surface or ground water." Another finding is that there are large amounts of lead in the trees near...Sea change: Skeletons of ancient corals different from today's
...cing chemical shock in the unfamiliar seawaters, I learned that they must be acclimated gradually, in stages," Ries said. "This was actually one of the most challenging aspects of the project. There were many failed attempts before I was able to keep the corals alive, so that I could observe their growth and...UCSD researchers find effective treatment for unusual fever syndrom caused by cold exposure
...et out in the cold air. I feel miserable, but I've learned to live with it. Having a hot tub to warm up helps!" Fowler and her two daughters with FCAS were among the individuals who participated in Hoffman's study at UCSD. With the other study participants, they spent 45 minutes in a cold-storage ...Sex versus survival: A tradeoff at geographical range limits
...a benign greenhouse environment, the research team learned that the reproductive switch is due to genetic factors causing sexual sterility. These sterility mutations can spread in northern populations because the harsher environment makes sex relatively unsuccessful compared to asexual clonal reproduction (w...November nutrition news from the Friedman School of Nutrition Science and Policy at Tufts
...Taylor notes that since that time, scientists have learned of its role in numerous cell functions. The ubiquitin pathway also plays major roles in many other cellular processes such as cell division, DNA repair, immune functions, and even gene expression, which determines what kind of cell a progenitor , or ...Community living causes bacteria to diversify
...y of Iowa researchers show that even bacteria have learned this important lesson. When disease-causing bacteria assemble into communities known as biofilms, the individual bacteria rapidly diversify. This diversity increases the capabilities of the group and provides a form of "biological insurance," which p...JCI table of contents, November 15 2004
...n became widely known in the 1970's when the world learned of David Vetter, a boy with SCID who lived for 12 years in a plastic, germ-free bubble. A number of genetic abnormalities can cause SCID. The two most common forms are linked to the X chromosome. Patients with abnormalities on this chromosome eit...New gene mutation found to cause 'bubble boy disease'
...n became widely known in the 1970's when the world learned of David Vetter, a boy with SCID who lived for 12 years in a plastic, germ-free bubble. A number of genetic abnormalities can cause SCID. The two most common forms are linked to the X chromosome. Patients with abnormalities on this chromosome either ......ounds the end of a chromosome, the scientists have learned how the protein homes in on a specific DNA sequenc...ere the telomeric DNA can fit. They also learned that while the protein would bind to a ten-nucleotide sequence, the structure could also accommodate...