Study begins to reveal clues to the cause and progression of sepsis
...to sepsis. To gain a better understanding into the mechanisms behind the condition, the researchers conducted the Genetic and Inflammatory Markers of Sepsis study (GenIMS), which collected extensive clinical and laboratory data geared to help analyze the risks of a person developing sepsis and dying. Data were ...Unravelling new complexity in the genome
...vides a valuable basis for understanding molecular mechanisms by which genes can function differently in different parts of the body. Blencowe attributes these new findings in part to the power of a new tool that he, together with his colleagues including Profs. Brendan Frey (Department of Electrical and Comp...Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
...ncer Cell, provides new insight into the molecular mechanisms that underlie aberrant NF-κB activity in MM t...ated in various types of cancer, but the molecular mechanisms involved are not well understood. Two separate research groups used a variety of sophisticated genom......of injection) in order to understand the molecular mechanisms underlying this invasive behavior. They identified the neurotrophin receptor p75NTR, which normally functions during development to induce neurite outgrowth and promote neuronal cell death, as an important regulator of glioma invasion. The researcher...Features of replication suggest viruses have common themes, vulnerabilities
...al genome while safe from surveillance and defense mechanisms of the host. " The virus has developed a very elegant strategy," says Ahlquist. "It creates for itself a new compartment for RNA synthesis, where it can collect its (constituent) components, organize successive steps of replication, and sequester t...Doernbecher Children's Hospital scientist earns coveted Javits award
...School of Medicine. Back's research looks at the mechanisms responsible for causing whitematter brain injury in developing infants. White matter brain injury isthe underlying basis for cerebral palsy, or CP, a condition in whichpermanent brain damage causes movement disorders, including inability towalk witho...Does the desire to consume alcohol and tobacco come from our genetic makeup?
... behind alcohol and tobacco use may point to novel mechanisms for blood pressure modification by these substances.) The volunteers were from the Saguenay-Lac-St. Jean region of Quebec, Canada. The locale, which is relatively isolated, somewhat genetically homogenous, and has kept genealogical records of its cit...New textbook illuminates the close links between evolutionary and molecular biology
...vels. They illuminate evolutionary principles and mechanisms with examples from across the spectrum of lifefrom...ast 3.5 billion years, and explain the fundamental mechanisms underlying evolutionary change. The final section is devoted to human evolution and diversity, merg...Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...and progression of Alzheimers, including the basic mechanisms of aging, genetics, biomarkers, inflammation and the impact of exercise and the environment. Award recipients include: Yaniv Assaf, Ph.D., Lecturer, Tel Aviv University: "Hippocampus characterization of mice over-expressing APP and APOE3/4 ...1 of deep ocean's most turbulent areas has big impact on climate
...the Atlantic Ocean. Better understanding of the mechanisms of mixing is crucial, says St. Laurent, an assistant professor of physical oceanography at FSU and the studys co-principal investigator, because mixing produces the overall balance of water temperatures that helps control the strength of the Gulf Str...A study by the MUHC and McGill University opens a new door to understanding cancer
..., 9 August 2007 - An in-depth understanding of the mechanisms that trigger cancer cell growth is vital to the de... 3 issue of Molecular Cell provides a key to these mechanisms that may prove crucial in the future. The paper is co-authored by Dr Morag Park, Director of the MUH...Research shows skeleton to be endocrine organ
...r (glucose) and fat deposition through synergistic mechanisms previously not recognized. Usually, an increase in insulin secretion is accompanied by a decrease in insulin sensitivity. Osteocalcin, however, increases both the secretion and sensitivity of insulin, in addition to boosting the number of insulin-pro...Cardio exercise benefits in male vs. female hearts
...heart diseases are likewise unequal. The molecular mechanisms responsible for these differences are so far unkno...mones such as estrogen and testosterone. While the mechanisms behind the differences are unknown, the physiological differences are clear. A new study examining c...Research aims to identify markers for menopausal women at risk for deadly blood clot
...rom the female KEEPS study may shed light on these mechanisms involving men. Conclusion According to Dr. Miller, This type of research brings us closer to defining risk profiles for a specific health issue. Our hope is that it can lead to tools that will allow doctors to provide hormonal therapy for thei...Weizmann Institute scientists discover a control mechanism for metastasis
... of Science has now revealed new details about the mechanisms controlling metastasis of breast cancer cells. The...by the growth factor and the nature of the genetic mechanisms involved in cancer cell migration, a team of researchers pooled their knowledge and resources. This ...ASBMB taps 8 scientists and 1 politician for top awards
...ression events, as well as defined the enzymes and mechanisms involved in epigenetic regulation. The Merck Award is given to a researcher who makes outstanding contributions to research in biochemistry and molecular biology. Alexandra C. Newton (University of California, San Diego) will be presented with t...Link identified between Alzheimer's disease and glaucoma
...at causes Alzheimer's disease and one of the basic mechanisms behind glaucoma," says Dr Francesca Cordeiro from University College London, who led the study. Dr Cordeiro is also a consultant ophthalmologist at the Western Eye Hospital, London, specialising in glaucoma. "However, this doesn't mean that everyone ...Genetic analysis finds greater threat in frog-killing fungus
...ted that badly. We could then try to determine the mechanisms those frogs use to resist the pathogen." The study also found that the sites near Tioga Pass Road contained two similar populations of fungi. Because the lakes are 40 kilometers apart, the evidence is strong that movement of the fungi between the t...New mechanism links smoking to lung damage
... damaging hits. Finding and testing drugs or other mechanisms that can selectively block these unpaired channels offers a novel approach to disease prevention."...Disabling a sensory organ prompts female mice to act like male mice
...eagues promises to open a new window to the neural mechanisms that underlie gender-based behavior in animals by ... mice, Dulac explained. The new insight into the mechanisms that govern sexual behavior in animals gives science a new avenue to explore the molecular and physi...