JCI table of contents November, 2005
...Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods ...... The sense of taste informs the organism about the quality of ingested food. It comprises five sub-modalities that perceive sweet, salt, sour, bitter, and umami stimuli. The possibility for an additional taste modality directed to lipid has often been suggested because many animals exhibit a spontaneo...JCI table of contents: November 16, 2006
... Many diseases of the eye (such as retinopathy of prematurity (ROP) and diabetic retinopathy) that result in loss of vision are the result of the growth of abnormal blood vessels that leak and bleed. Current treatments are designed to prevent the growth of these abnormal blood vessels. However, the authors of a study using a mouse model of retinopathy suggest that an alternative treatment st...Other highlights in the November 15 JNCI
... ... ...<...Story tips from the Department of Energy's Oak Ridge National Laboratory, November 2006
... To see if your system or instrument will stand up to real-world stresses, put it through its paces in Oak Ridge National Laboratory's Environmental Effects Laboratory. The EE Lab boasts a suite of instruments and mechanisms that can simulate just about any insult the world can throw at a piece of equipment. Team leader Peter Chiaro said the project looks at and mimics real-world situations...Free article by Nobel Laureate in November MCP
... Dr. Fire was awarded the 2006 Nobel Prize in Physiology or Medicine along with Dr. Craig C. Mello for their discovery of RNA interference (RNAi). In the MCP paper, F...JCI table of contents: November 9, 2006
... ... In a study that appears online on November 9, in advance of publicati...Highlights from the November 2006 Journal of the American Dietetic Association
... Dietary Effects of Free School Breakfast for All Children...Offering free school breakfasts to all elementary school students regardless of income increases the likelihood that the children will consume a nutritionally sound breakfast, according to researchers...Other highlights in the November 1 JNCI
... ... Statins and fibrates are often used for prevention of heart disease, and some research has suggested trial participants taking these medications have a lower melanoma incidence. Robert P. Dellavalle, M.D., Ph.D., of the Department of Veterans Affairs Medical Center in Denver, Colo., and colleagues reviewed 20 randomized controlled trials in which statins or fibrates were used as...National Academies advisory: Two-day stem cell symposium begins November 7
... ...Tuesday, Nov. 7, 8:30 a.m. to 5:15 p.m., and Wednesday, Nov. 8, 8:30 a.m. to noo...JCI table of contents: November 23 2005
...... Childhood infection with Epstein-Barr virus (EBV) is often asymptomatic, while the same infection in adolescents and adults causes infectious mononucleosis (IM). Liisa Selin and colleagues from the University of Massachusetts Medical School now show how, in a strange twist of immunological karma, T cells specific to a previously encountered virus (such as the flu) may come back to haunt y...Other highlights in the November 16 JNCI
... ...Increased physical activity is associated with decreased breast cancer risk in both black women and white women, a new study has found.... ...Dozens of studies have examined the association between recreational physical activity and breast cancer. However, questions remain about whether a reduction in risk is observed in all population subgroups. To examine the association between physica...Story tips from the Department of Energy's Oak Ridge National Laboratory, November 2005
...... Climate change can have a significant impact on the amount of carbon stored in cropland soils around the nation, according to researchers at the University of Illinois at Urbana-Champaign and Oak Ridge National Laboratory. Results published recently in Geophysical Research Letters show that about 5 percent of the 868 million tons of carbon sequestered from no-till cropping practices in th...Highlights from the November Journal of the American Dietetic Association
The November 2005 issue of the Journal of the American Dietetic Association contains articles and research studies you may find of interest. Below is a summary of one of this month's articles. For more information or to receive a faxed copy of a Journal article, e-mail . ... ... ... ...Researchers at Boston University studied dietary patterns of 1,666 adult men to assess relationships between nu...JCI table of contents November, 2005
... ... ...The sense of taste informs the organism about the quality of ingested food. It comprises five sub-modalities that perceive sweet, salt, sour, bitter, and umami stimuli. The possibility for an additional taste modality directed to lipid has often been suggested because many animals exhibit a spontaneous attraction for fats, but the existence of an actual sensor remained a matter of de...Other highlights in the November 2 JNCI
... ...Alcohol consumption is associated with an increased risk of estrogen receptor (ER)-positive, but not ER-negative, breast cancer in postmenopausal women, according to a new study.... ...Many epidemiologic studies have found an association between alcohol consumption and breast cancer risk, but it has not been known whether this risk varies by hormone receptor type. Alicja Wolk, Dr.Med.Sc.,...JCI table of contents November, 2005
... ... ...Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. High numbers of pDCs is related to successful control of HIV. In a paper appearing online on October 13 in advance of print publication of the November issue of the Jo...JCI table of contents November, 2005
...A NOVEL MECHANISM OF ACTION FOR LEAD ANTI-TUMOR AGENT ... ...Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months. Therefore, identification of unrecognized angiogenic pathways that selectively support tumor neo-ve...Wiley to publish new edition of Textbook of Biochemistry in November 2005
Hoboken, NJ, July 25, 2005 Global publisher John Wiley & Sons, Inc., today announced the November 2005 publication of the sixth edition of the Textbook of Biochemistry with Clinical Correlations, a benchmark textbook in the field of mammalian biochemistry for undergraduates, graduates, and students in professional schools....... Edited by Thomas M. Devlin, Textbook of Biochemistry with Clinical...National Academies news: Conference on genomics revolution set for November 2005
WASHINGTON The National Academies Keck FUTURES INITIATIVE announced today it will begin accepting applications from researchers for "The Genomic Revolution: Implications for Science and Health," a conference to be held Nov. 10-13, 2005, in Irvine, Calif. Applications must be submitted by June 2 and those selected to attend the conference will receive an invitation in late July. The FUTURES IN...Other highlights in the November 17 JNCI
...... A new study finds that higher levels of selenium in the blood may be associated with a decreased risk of colorectal cancer....... Selenium is a trace element found in meats and grains, but dietary intake can vary by geographic area because of different concentrations of the element in the soil. People living in regions where selenium intake is low have higher rates of several cancers, inc...JCI table of contents, November 15 2004
New gene mutation found to cause "bubble boy disease"... ...Approximately one in every million people develop a group of inherited disorders known as severe combined immunodeficiency (SCID) or "bubble boy disease". Characterized by inherited abnormal changes in B and T cells of their immune system, these individuals often suffer from numerous serious or life-threatening infections that are often...November nutrition news from the Friedman School of Nutrition Science and Policy at Tufts
...... Most people, scientists included, had not heard of the protein ubiquitin until a few weeks ago when the 2004 Nobel Prize in Chemistry was awarded to three scientists for their groundbreaking work on the subject. While it might not become a household word overnight, the Nobel Prize award certainly means that ubiquitin will become better understood and more prominent in scientific research.......... Assessing how quickly the body metabolizes the drug midazolam combined with genotyping could help to optimize irinotecan chemotherapy, according to a new study....... Irinotecan has been approved for use as part of first- and second-line chemotherapy for colorectal cancer and also has moderate activity against breast cancer, relapsed or refractory non-Hodgkin lymphoma, and lung cancer. Re......... High cholesterol levels are a major contributor to heart disease in particular atherosclerosis. High density lipoprotein (HDL) has an essential role in reducing cholesterol levels, and therefore has a cardioprotective effect. There is therefore a great deal of research into the genetic underpinnings that control HDL blood levels. Individuals with Tangier disease have essentially no HDL...