Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...on early neuronal signaling alterations that occur prior to the onset of beta amyloid plaques and tangles, and impairments in memory function. Specifically, she will try to determine the role of early calcium signaling defects in AD, and, to determine if normalizing this calcium defect can reduce the late...Sugar and spice and everything nice: Health differences in newborn girls and boys
...e the baseline levels of metabolites in both sexes prior to isolating the hearts. The hearts were then subjected to 60 minutes of normothermic ischemia and left ventricular biopsies were collected at the end of the period. All tissues were analyzed for adenosine adenosine triphosphate (ATP; the main energy...Inflammation may cause preterm labor and fetal deaths
...ve brought about the fetal death in mice. In a prior mouse study at Case Western Reserve, the investigators noted that inflammation closely paralleled localization of bacteria. In the present study, the researchers found that mice deficient in TLR4 lacked the necro-inflammatory response to bacteria an...Census of Marine Life historians detail collapse of bluefin tuna population off northern Europe
...hern waters of the eastern Atlantic and complement prior data showing that the western and eastern stocks of north Atlantic bluefin mingle in rich foraging grounds of the central Atlantic, says Barbara Block, chief scientist of the CoML Tagging of Pacific Predators program and TAG. Its possible all thr...Progesterone injections do not prevent preterm birth in twin pregnancies
...dy, 655 healthy women with twin pregnancies and no prior preterm births received weekly injections of eithe...reducing the rate of preterm birth in women with a prior spontaneous preterm birth, but not in women carrying twins is a question that will be answered only ...Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
...M.D., women with short cervix (most of whom had no prior history of preterm birth) who received progesterone suppository treatment between 24 and 34 weeks gestation had a greatly reduced rate of preterm birth. Another large multi-center trial led by Dwight J. Rouse, M.D., found that weekly injections of ...Nanotechnology helps scientists make bendy sensors for hydrogen vehicles
...rfaces of the pipe can detect any hydrogen leakage prior to diffusion to alert control units to take action. Flexible hydrogen sensors show a change of 75 percent in their resistance when exposed to hydrogen at a concentration of 0.05 percent in air. The devices can detect the presence of 1 percent hydro...Reading a face is tricky business
...ions -- were shown for 30 milliseconds immediately prior to each surprise face. The expressions of surpr...rime faces with other expressions briefly appeared prior to the surprise faces. Our results show that an unconsciously perceived signal of threat, such as...High rates of HIV infection documented among young Nepalese girls sex-trafficked to India
...ed 60 percent among girls forced into prostitution prior to age 15 years. One in seven of the studys participants had been trafficked into sexual servitude prior to this young age. Approximately 600,000 to 800,000 people are trafficked across the globe every y...Insulin grown in plants relieves diabetes in mice; UCF study holds promise for humans
...ing normal levels of insulin. Those results and prior research indicate that insulin capsules could someday be used to prevent diabetes before symptoms appear and treat the disease in its later stages, Daniell said. He has since proposed using lettuce instead of tobacco to produce the insulin because th...Report recommends off-site disposal of secondary waste
... used to wash work areas and decontaminate workers prior to removal of their suits. They are analyzed for contaminants, treated if necessary, and disposed of either on- or off-site. The committee found that disposal of these spent solutions does not present a significant challenge for the currently opera...Learning a second language -- Is it all in your head?
...ants aged 18 to 26 who had their brain scans taken prior to participating in the pseudo second-language training were previously participants in two related studies published by Wong and his research team. The three studies have identified behavioral, neurophysiologic and, with the current study, neuroanat...Success rates for prostate cancer depend on experience of surgeon
...inexperienced surgeons (for example, those with 10 prior operations) were nearly 70% more likely to have evidence of recurrence of their prostate cancer within five years than those whose surgeons had performed 250 operations (17.9% vs. 10.7%). Our findings also have implications for education in surgic...Adult survivors of childhood leukemia exercise less, worsening high risk for obesity and illness
...ipated in physical activity or exercise during the prior month. The study found that adult ALL survivors were less likely to meet the CDC physical activity guidelines (52.8 percent vs. 48.2 percent) and more likely to report no moderate or vigorous physical activity during the month preceding the survey...Neurons for numerosity: Parietal neurons 'sum up' individual items in a group
...rdinal number, such as 4, as have been reported in prior studies. These findings support computer models that separate the processes of summing and numerical identification, and may also explain the fact that parietal cortex damage causes both numerical and spatial confusion. ...'Preconditioning' helps protect brain's blood vessels from stroke
...he brain's vasculature, as well" Based on their prior work, the researchers knew that the protective effect of preconditioning relies on a ubiquitous chemical in the blood called nitric oxide (NO). Injuries to tissues -- such as the ischemia that occurs in stroke -- activate certain enzymes that produce...Scientists to make news at Computational Biology Conference
...n of 14 half-day tutorials will be held on July 21 prior to the opening reception. Welcome ceremonies for the main meeting will be held on the morning of Sunday, July 22. In parallel with the plenary sessions of the main meeting, there will be several alternative, parallel "tracks" of special interest to s...Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer
...ing chemotherapy and radiation to a treatment plan prior to surgery in individuals with oesophageal cancer, according to a study published last month in the Annals of Surgery. The authors say their finding is particularly important because the focus of recent pathological studies of response to neoadjuvant...JCI table of contents: July 12, 2007
... cells, or clonotypes, soon after immunization and prior to disease onset: BV8S2/BJ2S7 and BV16/BJ2S5. The BV8S2/BJ2S7 clonotype was found in far greater excess, disappeared with disease recovery, and was found to transfer disease to other healthy mice. The second clonotype, BV16/BJ2S5, persisted following......anglion (DRG) neurons. The expression was greatest prior to myelination. Using Campenot chambers, the authors report that BDNF was secreted from the compartment containing DRG axons as well as the cell body compartment, consistent with anterograde transport and secretion from the surface of the axons. Vira...