News tips from the Journal of Neuroscience
... Attila Gulys-Kovcs, Heidi de Wit, Ira Milosevic, Olexiy Kochubey, Ruud Toonen, Jrgen Klingauf, Matthijs Verhage, and Jakob B. Srensen... , Munc18 binds the "closed" state of syntaxin1 and thus occludes binding of the SNARE proteins SNAP-25 and synaptobrevin. However, Munc18 cannot be simply a negative regulator of exocytosis because vesicles fail to dock in its absence. To address this issu...National Ecological Observatory Network featured at ESA/SER Joint International Conference
... ... Dr. David Schimel (NEON CEO) will convene...American buffalo slaughter fueled by international trade
... In a working paper for the National Bureau of Economic Research, University of Calgary environmental economist M. Scott Taylor argues that the story of the buffalo slaughter on the Great Plains is not, at bottom, an American one. Instead, Taylor argues that the slaughter of some 30 million bison over the course of a decade was initiatied by a...... ... ... Dr. Yokoyama and colleagues developed a cell-free system using extrac...News tips from the Journal of Neuroscience
... ... Much has been written about the subunit composition of hippocampal NMDA receptors and their differential contributions to functions ranging from learning to neurodegeneration. Although NMDA receptors can be di-heteromeric, two NR1 subunits and two identical NR2 subunits, they can also be tri-heteromeric, containing NR1, NR2A, and NR2B subunits. Al- Hallaq et al. set out to examine recep...MicroRNA works with Ago2 protein to regulate blood cell development
... While microRNAs are made in large amounts in every cell from plants to humans, Dnal OCarroll, a research associate in Alexander Tarakhovskys lab at The Rockefeller U...News tips from the Journal of Neuroscience
... ...Rhona Seijffers, Charles D. Mills, and Clifford J. Woolf ... Injury of peripheral axons results in a regenerative response from the central as well as the peripheral process of a dorsal root ganglion (DRG) neuron. This conditioning effect is mediated by altered transcription of multiple genes and involves both enhanced axonal growth and reduced inhibition by myelin. Seijffers et al. con...Alternative farming cleans up water
... Nitrogen is one of the most important elements required in agricultu...CRESIB coordinates an international consortium to fight malaria caused by Plasmodium vivax
in CRESIB under...News tips from the Journal of Neuroscience
... ...Mu Sun, Mark J. Thomas, Rachel Herder, M. Lisa Bofenkamp, Scott B. Selleck, and Michael B. OConnor ... Bone morphogenic protein (BMP) has diverse functions in cell signaling from development to cell death. This week, Sun et al. focused on its possible role in synaptic plasticity by targeting the endogenous BMP antagonist chordin. The BMPRII receptor protein was expressed throughout the...New research seeks to enhance alternative fuel integration in public vehicle fleets
... RITs Center for Integrated Manufacturing Studies will work with the County Department of Environmental Services to analyze the environmental and economic impact of these vehicles and assist the county in determining a future course for the integration of additional alternative en...Tips from the Journals of the American Society for Microbiology
... ... Helicobacter pylori is a bacterium that colonizes the digestive tract of 50% of the worlds population. Infection commonly occurs in early childhood and can lead to chronic gastritis, peptic ulcer diseas...Journalists can register now for ECCO 14 -- the European Cancer Conference
... ... ECCO is recognised as one of the worlds leading multidisciplinary cancer conferences and provides a unique European forum for presentations of exciting new research from experimental and clinical oncologists, epidemiologists and cance...Journal of Alzheimer's Disease achieves significant impact factor
... Editors-in-Chief George Perry and Mark A. Smith commented, We are extremely pleased to have quantitative evidence of the high regard in which the Journal of Alzheimers Disease is...News tips from the Journal of Neuroscience
... Benjamin K. Ng, Lian Chen, Wilhelm Mandemakers, Jos M. Cosgaya, and Jonah R. Chan... Although neurotrophic factors are usually considered to be target-derived secretory products that are then retrogradely transported to their site of action, this week Ng et al. provide more proof that BDNF can move in other directions. The authors examined the source of BDNF necessary for Schwann cell-media...Penn researchers discover how microRNAs control protein synthesis
... Scientists estimate miRNAs have the ability to regulate the expression of approximately one third of human genes, and previous studies have linked abnormal activity of miRN...Internal clock, external light regulate plant growth
... Using time-lapse photography, postdoctoral researcher Kazunari Nozue, with colleagues from UC Davis and the University of Lausanne, Switzerland, found that the shoots of Arabidopsis seedlings show a spurt of growth once a day. The timing of that growth spurt is controlled by both the plant's internal clock and by exposure to light, acting on two...Highlights from the July 2007 Journal of the American Dietetic Association
CHICAGO -- The July 2007 issue of the Journal of the American Dietetic Association contains articles and research studies you may find of interest. Below is a summary of some of this months articles.... ... ... The researchers showed nearly 5,000 children a variety of portion sizes of french fries, meat, cooked vegeta...News tips from the Journal of Neuroscience
...Qian Cai, Ping-Yue Pan, and Zu-Hang Sheng ... If you are planning to ship Piccolo, Bassoon, and a bit of N-cadherin and SNAP- 25, you will need some syntabulin, according to Cai et al. this week. Piccolo and its active zone (AZ) compatriots are transported by a complex, which includes syntaxin-1, the kinesin motor KIF5B, and the adaptor protein syntabulin. In fetal rat brains, vesicles conta...Regulating alternative splicing during neural development
... ... Polypyrimidine-tract binding protein (PTB) is a well-known inhibitor of alternative splicing in various cell types. A neuronal version of PTB - called nPTB - is expressed solely in nerve cells, but its function...Journal of Nuclear Medicine's impact grows, remains consistently high over past 5 years
... JNM is ranked in the top 5 percent of all imaging journals based on its impact factor, which rose to 4.986 from 4.684 in 2005, placing it ahead of other imaging journals such as Human Brain Mapping, Seminars in Nuclear Medicine, the International Journal of Radia...News tips from the Journal of Neuroscience
... La Siksou, Philippe Rostaing, Jean-Pierre Lechaire, Thomas Boudier, Toshihisa Ohtsuka, Anna Fejtov, Hung-Teh Kao, Paul Greengard, Eckart D. Gundelfinger, Antoine Triller, and Serge Marty... This week, Siksou et al. give us some close-up views of the cytomatrix in presynaptic terminals. To catch synaptic vesicles and particularly their filamentous network in the act, the authors immobilized...2 MSU professors spearhead international water project
... ... With the biggest funding of its kind a $2.5 million grant by the National Science Foundation (NSF), the team leaders are bringing together domestic...UGR researchers design an alternative to blood test to detect drugs in the body
... ), coordinated by professor Antonio Hernndez Jerez, has developed a new t...International team to honor 30th anniversary of deep-sea vent discovery in Galpagos
... "The discovery of hydrothermal vents-ecosystems driven by chemical energy from the seafloor rather than energy f...Surprising origin of cell's internal highways
... Now, researchers at Vanderbilt University Medical Center reveal a surprising new origin for these cellular "highways." In the June issue of Developmental Cell, Irina Kaverina, Ph.D., and colleagues report that the Golgi apparatus -- a stack of pancake-shaped compartments that sorts and ships proteins out to their cellular destinations -- is the...Tips from the Journals of the American Society for Microbiology
... ... Clostridium difficile is the leading cause of nosocomial diarrhea worldwide with more than 300,000 cases reported each year in the U.S. alone. The recent emergence of a new highly virulent strain has increased the need for effect...News tips from the Journal of Neuroscience
... ...Melissa R. Regan, Yanhua H. Huang, Yu Shin Kim, Margaret I. Dykes-Hoberg, Lin Jin, Andrew M. Watkins, Dwight E. Bergles, and Jeffrey D. Rothstein ... , Regan et al. used bacterial artificial chromosome (BAC) transgenes to visualize the expression pattern of two glutamate transporters in mice, glutamateaspartate transporter (GLAST) and glutamate transporter-1 (GLT-1). These two transport...Yale journal examines the global impact of cities
... ....News tips from the Journal of Neuroscience
... Judith Blanz, Michaela Schweizer, Muriel Auberson, Hannes Maier, Adrian Muenscher, Christian A. Hbner, and Thomas J. Jentsch... . This widely expressed chloride channel is activated by cell swelling, l...Scientists decode RNA mystery, will help aim drug therapies
A team of University of Maryland scientists have made a discovery that will help better direct drug therapies to their molecular targets. ... ... Although these two terms have been used by scientists for over...June 2007 issue of the Journal of Ultrasound in Medicine focuses on contrast-enhanced ultrasound
... In recent history, the AIUM has championed the cause to obtain approval for the use of CEUS in the United...International study points to new breast cancer-susceptibility gene
... The gene, known as PALB2, may play a role in only about 1 percent of breast cancer cases in the select population that was studied (Finnish women), but its discovery sheds light on the complex web of gene interactions that underlies the disease, say the authors of the study, which is being publis...Structure of iron regulatory protein-RNA complex solved
... ... The iron regulating protein, called IRP1, has two structural forms, each with important functions within t...Salmonella bacteria use RNA to assess and adjust magnesium levels
Researchers at Washington University School of Medicine in St. Louis have added a gene in the bacterium Salmonella to the short list of genes regulated by a new mechanism known as the riboswitch. ...... The Salmonella riboswitch is the first to sense and respond to a metal ion, substantially expanding the types of molecules that riboswitches can detect to help cells assess and react to their envi...Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
WASHINGTON, D.C. - Cancer researchers are working toward a future in which each patient's tumor will act like a crystal ball, revealing how oncologists should treat the cancer to obtain the best outcome. Currently, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery - or whether some of these patients have an indolent disease that does not even...Role of microRNA identified in thyroid cancer
The presence of only five tiny strands of RNA is enough to clearly distinguish cancerous thyroid tissue from otherwise normal tissue, scientists say. ...... The findings provide more evidence that an emerging set of RNA genes called microRNA (miRNA) is a powerful regulatory force in the development of cancer and other diseases. The study is published online in the Dec. 19 Proceedings of the Natio...MicroRNA gene that regulates lifespan found by Yale scientists
New Haven, Conn. -- Genes that control the timing of organ formation during development also control timing of aging and death, and provide evidence of a biological timing mechanism for aging, Yale researchers report in the journal Science. ......"Although there is a large variation in lifespan from species to species, there are genetic aspects to the processes of development and aging," said a...HHMI awards international research grants to 28 scientists
Tams Freund, a Hungarian neuroscientist, and 27 other exceptional scientists in eight countries have been selected to receive international research awards from the Howard Hughes Medical Institute (HHMI). This is Freund's third HHMI research grant. His first, in 1995, was pivotal in his decision to stay in Hungary despite prestigious job offers in the West. A second grant in 2000 enabled him to b...International team of scientists complete fungal genomic sequences
Humans have a love-hate relationship with the aspergilli, a group of about 185 different species of fungus: several species are human athogens, while others are the basis for the production of human food and industrial enzymes. Now, an international team of scientists have determined and compared the genome sequences of three aspergilli Aspergillus fumigatus, a potentially deadly human pathogen,...