Tag: "smallpox" at biology news
Research team develops nonhuman primate model of smallpox infection
...nificant progress in developing an animal model of smallpox
that closely resembles human disease, which will b...t of bioterrorism, antiviral drugs and an improved smallpox
vaccine are urgently needed. Because the disease no longer occurs naturally, vaccine and drug candi...
Mayo Clinic awarded major NIH contract for smallpox genomics research
...ederal contract to study genetic susceptibility to smallpox
and genomic-based risks to the smallpox
vaccine. "This award underscores the confidence of the National Institutes of Health in our researc...
HHS awards $232 million in biodefense contracts for vaccine development
...e the greatest threat to national security. The smallpox
awards continue advanced development work that beg...ed that MVA is nearly as effective as the standard smallpox
vaccine, making it a promising candidate for use in children and pregnant women as well as people wi...
New study on smallpox in monkeys reveals tactics of a killer
...s a rare glimpse of how, on a molecular level, the smallpox
virus attacks its victims. The findings shed light...s and drugs that would be needed in the event of a smallpox
bioterror incident. The study, led by David Relman, M.D., of Stanford University, is now online in t...
Tips from the Journals of the American Society for Microbiology
...unds that block a key step in the lifecycle of the smallpox
virus and have little toxicity to human cells. The...sue of the Journal of Virology. An outbreak of the smallpox
virus is considered to be one of the greatest threats facing the world today. No antiviral drug has...
Hudson's Bay Company fur trapping policies set stage for modern environmental struggles
... Indian population by introducing such diseases as smallpox
and measles. Schefke notes that in the first century of European contact, native populations declined by as much as 80 percent in parts of the Pacific Northwest and British Columbia. And along the lower Columbia River, the Indian population shrank b...
Balancing 'hysteria and suspicion': Doctors face new responsibilities in 'bioterrorism era'
...programs and community drills (such as a simulated smallpox
scenario Evans and Clements developed for the CDC ...e how things may unfold in an atypical outbreak of smallpox
and how different their work environment might be. "In a bioterrorism incident, physicians...
UCI researchers create new technique for speeding development of vaccines
...p the live virus that is used to vaccinate against smallpox
today. Humans react strongly only to these 11 prot...he best way to blunt a bioterrorist threat against smallpox
and other dangerous organisms that terrorists can use as weapons. "The existing live-virus vaccine ...
JCI table of contents
in its tracks: a new anti-viral approach Natural or deliberate exposure to smallpox
poses a great health threat, especially since routine smallpox
vaccinations have been discontinued a...
Blocking cell signaling can stymie viral infections, study shows
... drug capable of treating people infected with the smallpox
virus, it could eliminate the virus' potential as ...o block a key signal in the cell machinery used by smallpox
and similar viruses to propel themselves from infected cells and to reproduce in new cells. In labor...
Stopping smallpox in its tracks: A new anti-viral approach
Natural or deliberate exposure to smallpox
poses a great health threat, especially since routine smallpox
vaccinations have been discontinued and no clinically approved treatment currently exists. In the F...
Preparing for the inevitable: New book for nurses guides patient care during a disaster
...ered a list of nurses willing to volunteer to give smallpox
vaccinations should mass immunization become necessary. Driven by the Sept. 11 terrorism attacks, Langan collaborated on "Preparing Nurses for Disaster Management" with Dotti James, Ph.D., associate professor of nursing at Saint Louis University. The...
Biologists discover why 10% of Europeans are safe from HIV infection
...ntists have suggested this disease could have been smallpox
or even bubonic plague but bubonic plague is a bacterial disease rather than a virus and is not blocked by the CCR5-32 mutation. Professor Duncan commented: "The fact that the CCR5-32 mutation is restricted to Europe suggests that the plagues of the ...
No serious adverse events found with next-generation smallpox vaccine
...II clinical trial of a next-generation vaccine for smallpox
suggest that the vaccine may provide immunity and ...ense Research Meeting. LC16m8 is a live attenuated smallpox
vaccine that is produced in cell culture from vaccinia virus that has been attenuated, or modified, ...
Secret of smallpox's success may lead to bioterror cure
...not only be able to create a vaccine that can cure smallpox
infections in their early stages, but he may also ...une systems. The ability to stay hidden allows the smallpox
virus, in particular, time to grow and multiply to the point of causing devastating disease before t...
Understanding biases in epidemic models important when making public health predictions
...ched Rohani to assist in the modeling of potential smallpox
introduction. "I noticed that when we assumed different distributions of the infectious period in the models, we observed very different epidemic curves," said the researcher. Conversations with Wearing and Keeling followed, alternative models were...
UF scientist finds unexpected link between cat and human AIDS viruses
...s against viruses from the same subfamily, such as smallpox
in humans, which is made from cowpox virus, and human measles vaccines for canine distemper in puppies. "Therefore, protective vaccines based on cross-reactive regions of AIDS viruses can provide broad immunity, and may be useful against viruses that...
LIAI scientists make major finding on potential smallpox treatment
...or advancement toward protecting society against a smallpox
outbreak by identifying an antibody in humans that quickly fights the smallpox
virus. "This is a very important finding because it has the potential to be an effective treatment...
The bioweapon is in the post
...difficult for a terrorist to obtain genes from the smallpox
virus, or a similarly vicious pathogen. Well, it's...tempt to order all the genes necessary to launch a smallpox
attack would probably arouse suspicion. "That would stand out from a technological point ofview," su...
New technique points to safer, more efficient vaccination
...xample, twenty percent of people immunized against smallpox
will suffer side effects. Wilfred Jefferies, a r...the team vaccinated mice against a relative of the smallpox
virus. Mice immunized with just one-hundredth the standard dose and induced to overproduce TAP were...