Saudi Arabia's KAUST names WHOI first research partner
...al reef health and identify regional environmental stress factors that make the reefs susceptible to disease, bleaching and death. The goal of the proposed WHOI-KAUST three-year fisheries and aquaculture project will be to develop an integrated bioeconomic model of the Red Sea coast of Saudi Arabia tha...Does the desire to consume alcohol and tobacco come from our genetic makeup?
...he area identified as being involved with pre-math stress DBP, they found a locus for alcohol on chr 4, inside gene GRID2, researchers found linked and associated SNPs for smoking moreover they found associated SNPs inside these gene for alcohol in males female-specific candidate SNPs were fou...High blood pressure, low energy -- a recipe for heart failure
...t heart health greatly depends on ERR alpha. "The stress of a cardiac pressure overload asks heart muscle to manufacture more high energy compounds, and without ERR alpha, they can't do it," explains Kelly, the Tobias and Hortense Lewin Professor and Chief of the Cardiovascular Division. "You could say tha...Antioxidant overload may underlie a heritable human disease
...first bona fide example of the role that reductive stress can play in disease. Reductants, sometimes refer...for similar deleterious effects. Indeed, reductive stress had been demonstrated in simpler organisms but not in mammals and/or disease states, he said. In t...New study suggests Concord grape juice may provide protection against breast cancer
...maintaining breast health by suppressing oxidative stress and inhibiting DNA damage to cells that can lead to the initiation of cancer, or in helping to slow the progression of breast cancer by slowing the multiplication of cancer cells. Diets high in natural antioxidants have been associated with a reduced...Preclinical study links gene to brain aneurysm formation
...reased blood flow, it attempts to reduce the shear stress to even levels by enlarging its luminal caliber through a process known as remodeling. This involves reabsorbing the inner layers of the vessel wall and forming new outer layers to replace them, explains Abruzzo. Although we dont fully understand ...New mechanism links smoking to lung damage
...his study, they looked at the effects of oxidative stress on unpaired (or non-junctional) hemichannels found...tion of these channels. "It required very little stress to open these channels," Lal said. "Substances found in smoke and other pollutants can alter the ele...Unlocking proteins from their cellular shell
PHILADELPHIA Applying physical stress to cells, researchers at the University of Pennsyl...ation. Cytoskeletal pliability within cells under stress has been a matter of guesswork in the past, however, and so a better understanding, achievable with ...JCI table of contents: August 1, 2007
... FoxO3 is required for the regulation of oxidative stress in erythropoiesis AUTHOR CONTACT: Saghi Ghaffari Mount Sinai School of Medicine, New York, New York, USA. Phone: (212) 659-8271; Fax: (212) 803-6740; E-mail: saghi.ghaffari@mssm.edu . View the PDF of this article at: https://www.the-jci.org/art...Cell damage caused by brushing may help keep gums healthy
...gene, an early-response gene often activated under stress that may be the first step in a response such as c.... Many tissues in our bodies respond to mechanical stress by adapting and getting stronger, like muscles. We think the gums may adapt to this mechanical stres...Military to study better pain relief in battle zones
...ot relieved adequately, can lead to post-traumatic stress disorders. A large multidisciplinary team of U-M scientists will use the grant to design multipurpose nanoparticles and test how well they perform several tasks under simulated physiological conditions in the laboratory. Ultimately, they want the p...Research shows NPD1 protects a key component of vision
...the retina and brain. DHA is a target of oxidative stress in pathological conditions and Dr. Bazans research...ter. The team decided to explore whether oxidative stress triggered by another experimental condition, called serum starvation/H2O2/TNF,, would be similarly i...Prenatal stress keeps infants, toddlers up at night, study says
...tress, which is associated with increased exposure stress hormones, like cortisol, may disrupt a childs formation of a bundle of nerve cells in the brain called the suprachiasmatic nucleus which act as a signaling system that tunes bodys internal clock. This signaling system helps to properly regulate dai...Gene-transcription machinery seen poised for action, held in check until needed
...for nearly instantaneous activation in response to stress or other vital needs. Embryonic stem cells, for example, are known to have numbers of genes held in this state of readiness. In their investigations, the scientists were able to identify a single molecule called ubiquitin that, when in place, appea...Air pollution link to clogged arteries
...y generating reactive oxygen species and oxidative stress when combined with oxidised phospholipids in the arteries. This can lead to vascular inflammation, which can in turn lead to increased lesions in the clogged arteries, potentially giving rise to blood clots that trigger heart attack or stroke. Thes...Effects of aging in stem cells
... found that genes involved in the inflammatory and stress response became more active with age, while genes ...e how epigenetic regulation, inflammation, and the stress response interact to better understand the molecular mechanisms of aging, and why so many of us face...Alternative farming cleans up water
...ater can contribute to waters becoming hypoxic and stress aquatic life living downstream. The challenge facing industry, farmers, agricultural advisors, and others concerned about the environment is to develop efficient cropping systems that maintain economical production levels while minimizing surface a...A brain chemical that battles despair
...sants work on the brain circuitry involved in such stress response. Led by Eric Nestler, the researchers p...nd his colleagues showed that exposure to repeated stress caused an increase in a protein called ∆FosB in the brain. This protein is a "transcription fa...Purdue-IU researchers explore new method for early disease diagnosis
... metabolites can indicate a response to biological stress or a specific disease state. "The metabolic profile in biofluids, such as blood and urine, provides a snapshot of ongoing biological processes in the human body," Raftery said. "This type of analysis could be a key to earlier detection of diseases....Cardiac patches stimulate regeneration, improve function after heart attack
...hocardiograms, and decreased left-ventricular wall stress on catheterization. They also had less scarring of heart tissue, a reduction in infarct size and a denser network of blood vessels feeding the area. In contrast, the rats receiving Gelfoam alone showed little if any improvement. At the cellular lev...