Tag: "abnormalities" at biology news
Immune systems in breast cancer survivors who suffer from fatigue fail to shut off after therapy
... A small study at UCLA had previously demonstrated abnormalities
in immune activation in breast cancer survivors. If researchers could determine the biological factors underlying this activation, and therefore fatigue, they could uncover a biomarker for the condition that could help them predict which patients wou...
New findings help pinpoint autism's genetic roots
...m disorders. The investigators also found physical abnormalities
in the brains that mimic some cases of autism, showing that the research animals can be useful in studying the mysterious condition. The finding to be published in the May 4 issue of the journal Neuron confirms recent indications that a mutation i...
Mutant mice show key autism traits
... learning and memory. The mutant mice showed major abnormalities
in a variety of social interactions normally undertaken in mice, found the researchers. For example, they were far less likely to approach and sniff new mice introduced into their cage, compared to normal mice. And while normal mice show markedly les...
Scientists develop ENDEAVOUR − a computer program for identifying disease genes
...he infants have deformed features and blood vessel abnormalities
in the heart. ENDEAVOUR identified one gene as a p...EL1 gene. The embryos of these fish showed several abnormalities
that are comparable to the symptoms of DiGeorge syndrome. This study provided the ultimate proof tha...
Fox Chase study sheds light on cancer susceptibility and disease involving bone-marrow failure
...luding lymphoma; and, starting as early as age 10, abnormalities
of skin, nails and mucous membranes that resemble premature aging syndromes. The majority of patients are male. The Fox Chase researchers used a variety of approaches to study the Dkc1 mutation in cells from humans with dyskeratosis congenita and in...
Full year of treatment helps infants and children with toxoplasmosis
...hty percent of these infants (96/120) had clinical abnormalities
at birth, often severe. Patients were treated with...ons assessed neurologic status, including movement abnormalities
and cognitive function, vision, including the development of new lesions in the eye, and hearing los...
Test for dioxin sensitivity in wildlife could result from new study
...ls and have been linked to cancer and reproductive abnormalities
in humans. Dioxin was the primary toxic component of the defoliant Agent Orange, and was found at Love Canal in Niagara Falls, NY. In virtually all vertebrates, dioxin sticks or binds to the aryl hydrocarbon receptor, or AHR. Like any protein, AHR ...
Study shows that genetic quality of sperm deteriorates as men age
..., the researchers analyzed DNA damage, chromosomal abnormalities
and gene mutations in semen samples from the same subjects 97 healthy, non-smoking LLNL employees and retirees between 22 and 80 years old and found that sperm motility showed a high correlation with DNA fragmentation, which is associated with incr...
Loss of central vision with age may be linked to quality of dietary carbohydrates
...iences campus in Boston. "The likelihood of having abnormalities
characteristic of AMD on eye exam more than doubled for women who consumed diets with the highest glycemic index, regardless of other factors already known or suspected to increase the risk of AMD, such as age, high blood pressure, cigarette smoking,...
Study says lung cancer overdiagnosis a result of screening
...an detect very small lung abnormalities, but these abnormalities
may be clinically unimportant. The question remains as to whether early detection of lung cancer through mass screening results in a net benefit to the public's health." the authors write. In an accompanying editorial, Edward F. Patz, Jr., M.D., of...
Novel non-invasive imaging technology may allow precise diagnosis of coronary artery disease
...-and SPECT perfusion imaging--detecting blood flow abnormalities
in the cardiac muscle, he explained. "To the best of my knowledge these are the first results of cardiac SPECT/CT in a clinical setting," he added. "These initial results indicate that cardiac SPECT/CT imaging enables the precise localization of an ...
The downside to diversification
...eviously thought, and can generate the chromosomal abnormalities
found in human lymphomas. Using a novel and more biologically relevant experimental system, the scientists determined that in pre-B cells, about one out of every 50,000 V(D)J recombinations results in an unexpected, and potentially dangerous, transp...
New egg freezing technique offers hope to hundreds of women
...Rome, Italy, told the conference that a variety of abnormalities
became apparent when frozen-thawed eggs were inspected more closely, even in those that appeared undamaged after thawing. In addition, the type and/or concentration of agent that was used to protect the egg during freezing (cryoprotectant agent or CP...
How IVF could be causing genetic errors in embryos
...ted with certain developmental syndromes and other abnormalities
in growth and development, such as low birth weigh...dence shows that some neurological and behavioural abnormalities
are associated with assisted reproductive techniques. Cases of Angelman and Beckwith Wiedeman syndro...
New method of testing eggs for abnormalities could solve problems of embryo freezing
...woman's egg, before fertilisation, for chromosomal abnormalities
that might make an embryo less likely to implant successfully or more likely to miscarry at a later stage. The technique involves analysing the first polar body, a small membrane-bound cellular structure that is expelled from the mature egg (oocyte) ...
Study contradicts USA warning that an antidepressant can cause congenital abnormalities
...ular antidepressant, paroxetine, causes congenital abnormalities
if taken by pregnant women, the 22nd annual confer...to the drug. "We found that the rate of congenital abnormalities
was not increased after using paroxetine in early pregnancy. Three abnormalities
were reported after...
Microchannels, electricity aid drug discovery, early diagnosis
...ed picture of the cell population and can pinpoint abnormalities
more quickly and exactly." The size of the channel, while small enough to accommodate only one cell at its narrowest diameter, varies in width so that the electric field intensity differs depending on the cell's location in the device, Lu said. The f...
Chromosomal abnormalities in sperm higher after vasectomy reversal
...ersed have a very much greater rate of chromosomal abnormalities
in their sperm than do normal fertile men, a scien...estions, so we decided to study the rates of these abnormalities
in ejaculated sperm after vasectomy reversal. If these sperm continued to have a high rate of aneup...
Parkinson's disease mechanism discovered
...n Parkinson's disease. It had long been known that abnormalities
in alpha-synuclein could cause a lethal buildup of...-synuclein in yeast, so they could determine which abnormalities
arose earliest in the pathological process. Those experiments by Cooper revealed that an important e...
RSRF-funded research links Rett syndrome to mitochondrial gene
...l experiments are needed to link the mitochondrial abnormalities
to the symptoms found in the mutant mice. The rese... there have been clinical reports of mitochondrial abnormalities
in Rett Syndrome patients. Dr. Bird's research provides the first genetic link between MECP2 and mit...
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