Tag: "accelerated" at biology news
Protein 'chatter' linked to cancer activation
...rder, and Nijmegen breakage syndrome experience an accelerated
rate of loss of DNA from chromosome ends. We didnt know why this happens; now we have found that the communication link between these proteins and a protein crucial for maintenance of chromosome ends is either missing or nonfunctional in these patien...
Geisinger scientist seeks cure for Lou Gehrig's disease, creating device to find treatment
...y bred and tends to exhibit diseases effects at an accelerated
rate. Yet the instruments needed to use these small and inexpensive fish for finding new drugs have not yet been brought to market. The students have developed a working prototype screening plate that allows scientists to quickly expose zebrafis...
JCI table of contents -- July 26, 2007
...striking body-wide accumulation of cholesterol and accelerated
atherosclerosis. This observation suggests that LXR-beta alone is unable to maintain homeostasis under conditions of cholesterol overload. Surprisingly, however, administration of a synthetic compound that activates LXR-beta, was able to compensate f...
Story tips from the Department of Energy's Oak Ridge National Laboratory
... approaches can be effective, Bloom noted that the accelerated
anaerobic bioremediation of tetrachloroethene and trichloroethene has exceeded their expectations. Funding for the effort is provided by DOD. [Contact: Ron Walli, (865) 576-0226; email@example.com ] Homeland Security Bio watchdog . . . Effec...
Military bases can benefit by addressing sprawl issues and biodiversity
... but the programs funding and activities should be accelerated
before land development hinders future buffering opportunities, according to a RAND Corporation report issued today. The Office of the Secretary of Defense asked the RAND Corporation, a nonprofit research organization, to assess the effectiveness o...
Biovest announces interim blinded data of fast-tracked pivotal Phase 3 clinical trial of BiovaxID
...centers and 8 centers in Russia. Applications for accelerated
conditional approval of BiovaxID are planned to be submitted to both the Food and Drug Administration (FDA) and European Medicines Agency (EMEA) by mid-2008. The DMC has agreed to serve as a liaison between the Company and the FDA and the EMEA. If ...
Interim analysis of anti-cancer vaccine, BiovaxID, to be conducted
...:ABPI) announces a milestone in its effort to gain accelerated
conditional approval for BiovaxID. The independen... will be supportive of its planned application for accelerated
conditional approval of BiovaxID. BiovaxID is an anti-cancer vaccine that is in pivotal Phase 3 Cli...
Major study predicts grim future for Europe's seas
... every sea, we found serious damage related to the accelerated
pace of coastal development, the way we transport our goods and the way we produce our food on land as well as the sea. Without a concerted effort, to integrate protection of the sea into Europes development plans, its biodiversity and resources w...
Extra-aggressive form of idiopathic pulmonary fibrosis identified
...ration of symptoms before diagnosis and display an accelerated
clinical course to end-stage disease. The authors postulate that these "rapid progressor" patients, predominantly smoking males, represent a distinct clinical phenotype compared with the usual "slow progressors" patients. "These findings highl...
Growth factors and environment combine to increase brain maturation
...particular that maturation of the visual system is accelerated
in an enriched environment, where animals can expl...-I), has been found to be capable of mediating the accelerated
maturation of cortical development produced by enriched environment. The present work suggests that ...
World's leading scientists announce creation of 'Encyclopedia of Life'
...a, have been underway since January 2006, work has accelerated
due to the support provided by the John D. and Catherine T. MacArthur Foundation and the recent discussion of the Encyclopedia of Life by renowned biologist Edward O. Wilson at the March 2007 Technology, Entertainment, Design (TED) Conference. One ...
Story ideas from the Journal of Lipid Research
...n involved in cholesterol metabolism may cause the accelerated
onset of Alzheimer's Disease in individuals affected with Down Syndrome. People with Down Syndrome a genetic disorder due to the presence of an extra chromosome 21 develop Alzheimer's disease (AD) earlier (mid- to late 30s) than the general pop...
New clues for treatment of disease that causes accelerated aging
...nt of a rare genetic condition that causes rapidly accelerated
aging and leads to an average life expectancy of 13 years. Scientists studying the genes of two infants who died of mysterious illnesses found the infants had mutations in LMNA, the same gene altered in patients with the premature aging condition pro...
Arctic ice retreating more quickly than computer models project
...reasingly rapid loss of ice in recent years, which accelerated
to 9.1 percent per decade from 1979 to 2006 according to satellite observations....
Satellites shed light on global warming
...ity's Professor Helmut Rott has been observing the accelerated
retreat and break-up of the Larsen Ice Shelf on th...s, where the buttressing ice had disappeared, have accelerated
significantly. The retreat of grounded ice and the accelerated
ice export due to increased velocity ...
Corn, oats, cherries and red wine's high melatonin content can help delay aging
...Both normal and genetically-modified mice, with an accelerated
cell ageing, were analysed. "We proved", says professor Acua Castroviejo, "that the first signs of ageing in animal tissues start at the age of five months [in mice] equivalent to 30 human years of age due to an increase in free radicals (oxygen an...
Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
...g pathways, they will then begin reproducing at an accelerated
rate, leading to a particularly aggressive form of cancer." The researchers believe further studies will identify new biomarkers that will enable physicians to clinically screen patients for mammary stem cells and provide specific treatments design...
JCI table of contents -- April 5, 2007
...levels of STARS in their heart muscle cells showed accelerated
heart failure under conditions that led to cardiac hypertrophy. At the molecular level, a protein known as MEF2 was shown to induce the expression of STARS, which, in turn, induced the expression of genes controlled by a protein known as SRF. This mo...
Treatment-induced growth factor causes cancer progression
...ansgenic mouse model of breast cancer dramatically accelerated
metastasis. Then they came across a few clinica...in and docetaxel all increased TGF-beta levels and accelerated
metastasis, an effect that was blocked by neutralizing antibodies directed against TGF-beta. Simi...
Almac Diagnostics announces pioneering genetic research on colorectal pre-malignancies
...ch tools are novel microarrays developed to enable accelerated
research in discovery, development and validation and ultimately to deliver clinical applications. As the first microarrays based around the transcriptome of an individual disease, this technology generates significantly more information, which is...
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