Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
...rtain fats in the diet, commonly known as omega-6, accelerates breast cancer, increasing the malignancy of the disease. The research team at the Departament de Biologia Cellular, de Fisiologia i d'Immunologia of the UAB has identified four genes, one which has a completely unknown function, whose expression may ...Globetrotting pollutants turn up on Toronto street
...(LAMS), which pulls in air from College Street and accelerates the pollutants to close to the speed of a bullet. As a particle passes by two lasers, sensors calculate its exact speed and tell the LAMS when to fire a third, high-powered laser that vaporizes a portion of the particle, sending fragments hurtling al...JCI table of contents, 3 January 2005
...tent infected cells (which promotes cell death and accelerates viral clearance) and combining this approach with intense antiretroviral therapy. In the January 3 issue of the Journal of Clinical Investigation, Roger Pomerantz, Giuseppe Nunnari, and colleagues from Thomas Jefferson University demonstrate that......tent infected cells (which promotes cell death and accelerates viral clearance) and combining this approach with intense antiretroviral therapy. In the January 3 issue of the Journal of Clinical Investigation, Roger Pomerantz, Giuseppe Nunnari, and colleagues from Thomas Jefferson University demonstrate that the......cells, glutathione, in turn, being an element that accelerates cellular proliferation. But this GSH compound is found in all cells and, therefore, in cancerous cells. And this is why the metastasis regenerates. Thus, in order to obtain beneficial effects using IL-2, the glutation in tumorous cells would have to ...New method simplifies search for genetic changes associated with disease
...oped a method called direct genomic selection that accelerates the transition between family or population-based studies of disease inheritance patterns and identification of genetic variations that may contribute to disease. That transition normally slows down dramatically when scientists have to sequence regio...Deficient DNA repair capacity associated with increased risk of breast cancer
... contributes to the accumulation of DNA damage and accelerates the genetic changes involved in carcinogenesis. To evaluate whether reduced DNA repair capacity in the nucleotide excision pathway that fixes DNA alterations known as bulky DNA adducts is associated with breast cancer risk, Regina M. Santella, Ph.D....JCI Table of Contents, March 1, 2005
...egulation of the protein protects kidney cells and accelerates their recovery from damage. Human kidney biopsies show extensive expression in the proximal tubule of kidneys damaged by ischemia and toxins. When a single dose of siderocalin was administered to the proximal tubule in the early stages of kidney di...NASA study finds soot may be changing the Arctic environment
...When soot falls on ice, it darkens the surface and accelerates melting by increasing absorbed sunlight. Airborne soot also warms the air and affects weather patterns and clouds. Koch and Hansen?s results suggest a possible mechanism behind the satellite-derived observations of Arctic climate change. They found...Noise and carbon monoxide exposure increases hearing loss according to Universit de Montral study
...s that the reduction of oxygen in the blood stream accelerates the deterioration of the sensory cells of the inner ear. Adriana Lacerda is currently finishing her doctoral thesis under the supervision of Professor Tony Leroux and Jean-Pierre Gagn of the cole d'orthophonie et d'audiologie at the Universit de Mo...Study finds obesity is associated with an impairment of coronary circulatory function
... and the mechanisms by which obesity initiates and accelerates vascular disease are still poorly understood," said Thomas H. Schindler, M.D., who works in the department of molecular and medical pharmacology at UCLA's School of Medicine. "Quantitative PET imaging--with the assessment of the functional stage of t...Study to determine if air pollution accelerates development of cardiovascular disease
...try to determine the degree to which air pollution accelerates development of cardiovascular diseases. "The results of this new study, called MESA Air, can be used in future efforts to better define air pollution standards on both an individual and community basis," said Gregory L. Burke, M.D., M.S., professor a...America's public forests landlocked by sea of development
...ects biodiversity, it impacts hydrology cycles and accelerates the spread of invasive species. Wildfires and animal-human conflicts are added risks. "It is possible that the national forests may not suffice for some endangered species," says Radeloff. Radeloff is not advocating a moratorium on building rural h...Tadpole soon to help in the fight against cancer and lymphedema
...ork can be studied with the help of tadpoles. This accelerates research of the lymphatic vessel network. With tadpoles one can now very quickly identify new genes that play a part in the development and functioning of the lymphatic vessel network. This is a first step in the search for solutions for illnesses re......have discovered that the loss of a gene called p63 accelerates aging in mice. Similar versions of the gene are present in many organisms, including humans. Therefore, the p63 gene is likely to play a fundamental biological role in aging-related processes. "To study how the p63 gene works, we devised a system for...JCI table of contents September 1, 2005
...lerosis. TITLE: Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice AUTHOR CONTACT: Ira J. Goldberg Columbia University, New York, NY USA Phone: 212 305 5961; Fax: 212 305 5484; E-mail: ijg3@columbia.edu View the PDF of this article at: https://www.the-jci.org/...Symptoms of depression may worsen heart failure
...ailure or if heart failure causes depression which accelerates inflammation." A study at Duke University found that patients with major depression are twice as likely to die or to be re-admitted to the hospital a second time within 12 months. "Patients with heart disease are prone to developing depression," Ferk...Molecular drug pump may help reduce risk of Alzheimer's
...sts found that the molecule, P-glycoprotein (Pgp), accelerates clearance from the brain of amyloid beta (A-beta) peptide, the primary component of the plaques that are the hallmark of Alzheimer's disease. According to scientists, the new link is potent and intriguing enough to suggest several potential follow-u...Winners of 2005 AAAS Science Journalism Awards
... for an elusive force that shapes the universe and accelerates its expansion. "Monastersky's work stands out for its meticulous explanatory reporting of a remarkably broad range of scientific controversies," said Robert Lee Hotz of the Los Angeles Times. "I am deeply honored that the judges selected my work for ......lgaris (PV). The authors show that intravenous Ig accelerates the degradation of pathogenic autoantibodies and prevents blistering. It does this by saturating the Fc receptor, FcRn. The results give new insights into the pathology of these types of diseases and suggest that FcRn is a promising therapeutic tar...