Tips from the Journals of the American Society for Microbiology
.... Toxin A initiates infection allowing toxin B to access underlying cells. In the study researchers developed a vaccine including anti-toxin A antibodies and transcutaneously immunized mice, some also with the cholera toxin and some without, over a period of 42 days. Mice immunized with both C. difficile...PINK1 protects from Parkinson's
... PD. In a study published this week in the open access journal PLoS Biology, Julia Pridgeon, Lian Li, and colleagues at Emory University show that PINK1 is a protein kinase that phosphorylates the mitochondrial molecular chaperone TRAP1 to promote cell survival. The researchers find that PINK1 normally p...Staphylococcus aureus hides out in cells
...o avoid detection. New research in the online open access journal BMC Genomics shows how S. aureus makes itself at home in human lung cells for up to two weeks. A team of 12 researchers from University Hospital of Geneva, Switzerland and the Institute of Food Research, Norwich, UK set out to uncover what ...Could fungal collection hold the key to new life-saving drugs?
... are delighted to be working with CABI and to have access to their fantastic source of fungal samples. We hope that this novel source of chemical diversity will contain new compounds that can be used to point the way to new drugs for serious diseases. CABI currently uses its fungal collection, along with ......he tool worked. The researchers gave the animals access to small rakes with either a rigid wooden head or a flimsy fabric head. Both enculturated and semi-enculturated chimpanzees correctly chose the rigid rake which enabled them to obtain the reward, indicating that both of these groups understood the p...UVa-led team uncovers important secret in gene replication
...his packaging determines how the cells enzymes get access to the DNA to read off the DNA and replicate, ultimately to create all of the proteins needed by a given cell. Several other researchers around the country were part of this larger project, the Encyclopedia of DNA Elements (ENCODE) project, using t...Vets seeing more horses with nutritional issues this year
...ose watch on their horses. Horses that do not have access to green grass and that are being fed old yellow hay are at risk. Usually, by the time the horse is showing symptoms of either problem, it may be too late to reverse the disease completely, Johnson said. However, if a horse owner has other horses t...Hormone that signals fullness also curbs fast food consumption and tendency to binge eat
...reat even while living in todays environment where access to high-caloric food is abundant every day. While this research is promising, it appears pramlintide will produce only modest weight loss, probably around 8%, before reaching a plateau. Amylin Pharmaceuticals clinical research program in obesity i...Conference to examine role technology can play in managing health care costs
...of care, managing health care costs and increasing access to affordable and effective health care throughout the world, Biotechnology Council Chair Dick Doyle said. The all-day conference will bring together key government, industry, academic and research leaders and patient advocates. This will help poli...Reprogrammed fibroblasts identical to embryonic stem cells
...stocyst that houses a supply of stem cells. But to access these cells, researchers must destroy a viable embryo. Now, scientists at Whitehead Institute have demonstrated that embryonic stem cells can be created without eggs. By genetically manipulating mature skin cells taken from a mouse, the scientists ...Human ancestors learned to walk upright in the trees, say experts
...of chimps and gorillas, however, tried to maintain access to the canopy as well as the ground by developing very strong arms to climb vertically up and down tree-trunks and as a consequence became top-heavy. When they are on the ground, therefore, they move predominantly by knuckle-walking, propping themsel...2nd International EuroFIR Congress
...y, healthiness and safety of European diets.Having access to quality and accurate compositional data about the food we eat is crucial to regulators, health policy makers, researchers, the food industry and the public. This second Congress will describe how EuroFIR (European Food Information Resource) is con...Philandering female felines forgo fidelity
...arge landscapes if females are to continue to have access to many males. In addition to helping save cheetahs in Africa, WCS is also studying the last remaining populations of Asias cheetahs in Iran....Climate change signal detected in the Indian Ocean
... South East Australia Climate Initiative, combined access to ocean observations using the volunteer 'ships o...ew of commercial ships, Australian scientists have access to a regular series of ocean measurements to a depth of 800 metres across the Indian Ocean. The te...Avian influenza survivors' antibodies effective at neutralising H5N1 strain
...esearchers. In a study published today in the open access journal PLoS Medicine, the researchers have shown how specific antibodies taken from avian flu survivors in Vietnam can be reproduced in the laboratory and prove effective at neutralising the virus in culture vitro and in mice. The H5N1 influenza v...Rapid syphilis testing in Haiti will prevent congenital disease and stillbirths
...he standard of care in rural Haitian areas without access to syphilis laboratory testing, is assessing sympt...for all pregnant women in Haiti who currently have access to prenatal care, over 1,000 cases would be avoided each year, along with over 1,000 stillbirths and...Research center unites biomedical competitors to fund medical technology development
...earch is complete, all industry partners will have access to the technologies." Haridas, associate profess...idas adds, "because it gives our industry partners access to unbiased research and the university countless opportunities for students to get hands-on trainin...CSHL links activity in brain synapses and developmental abnormalities with schizophrenia gene
...functionality of NRG1 was possible here because of access to powerful technology that combined the ability to manipulate individual genes, to study the very structure of the glutamate synapse with a two-photon microscope, and to perform functional studies using electrophysiology." Li hopes that his re......dy published in the journal PLoS Pathogens an open access journal published by the Public Library of Science Dr Pleass and his collaborators in London, Australia and The Netherlands describe how they got around the problem by creating a mouse model of the human malaria infection. They took a closely relate...... immediately upon publication. For other articles, access is limited to subscribers for the first 6 months after publication, and access will be free thereafter. The HFSP Journal is be published online and in print....