Protein's tail may be flu virus's achilles heel
... ......... ...UCSD biochemists discover bacteria's Achilles' heel
Researchers at the University of California, San Diego have determined what factors turn on protein production in bacteria, a finding that provides new targets for the development of antibiotics. ......In the study, published in the April 7 issue of the journal Molecular Cell, researchers Sean Studer and Simpson Joseph in UCSD's Department of Chemistry and Biochemistry report how the messenger R...Researchers develop new method to help find deadly malaria parasite's Achilles heel
Researchers at UCSD have discovered that the single-cell parasite responsible for an estimated 1 million deaths per year worldwide from malaria has protein "wiring" that differs markedly from the cellular circuitry of other higher organisms, a finding which could lead to the development of antimalarial drugs that exploit that difference. ...The scientists will report in the Nov. 3 issue of Nature...SAN FRANCISCO -- It's one of the most common viruses in America, and one that causes the most guilt and shame. It can get inside almost any kind of human cell, reproduce in vast numbers, and linger for years in the body, causing everything from recurrent genital blisters to sores around the mouth. Its complications can kill, and it may increase susceptibility to many nerve and brain disorders.......