Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process
...b is to unwind the tightly coiled chain of nucleic acids the DNA or RNA molecule that spells out the organisms genetic code so that another enzyme, a polymerase, can faithfully copy each nucleotide in the code. Researchers at the University of Illinois, Yale University and the Howard Hughes Medical Ins...UCLA study links air pollution to clogged arteries
...ion between diesel exhaust particles and the fatty acids found in low-density lipoprotein (LDL) cholesterol... chemicals containing free radicals, and the fatty acids in LDL cholesterol generate free radicals during metabolism in the cells, said first author Ke Wei G...Eat fish -- especially if you drink high levels of alcohol
Essential fatty acids (EFAs) are a necessary part of an individual's hea...the already very low EFA levels. Essential fatty acids (EFAs) are just that; an "essential" part of the total fat intake necessary for a healthy human diet...Coming soon -- Protein synthesis without amino acids?
...al amino acids. Like pearls on a string, the amino acids then line up. However, to get to such a structure, it isnt absolutely necessary to start from amino acids. Imines, compounds with a carbon-nitrogen double bond, could be an ideal starting materialif it were possible to link them together in an altern...Protein pulling -- Learning how proteins fold by pulling them apart
...ce proteins by stringing together strands of amino acids based on the sequences of their DNA. Proteins are ...he strand. However, knowing the order of the amino acids in the strand gives no clue about how a protein functions. That's because every protein folds into a...Exercise, exercise, rest, repeat -- how a break can help your workout
...trial also had a pronounced increase in free fatty acids and glycerol (chemical compounds that are released...ial, but this result may be because the free fatty acids concentration was already high before the recovery period. Conclusions The American College of...Purdue-IU researchers explore new method for early disease diagnosis
...t can be used to identify the molecules like amino acids in biofluids. Each metabolite has a unique pattern... "We added a chemical that reacts with the amino acids and similar metabolites and forms a tag that can be seen through nuclear magnetic resonance," he sai...Sour taste make you pucker? It may be in your genes
...s have long known that sour taste is stimulated by acids in foods and beverages. In fact, the word acid is derived from the Latin acidus, meaning sour. However, we still do not completely understand how the taste system is able to detect and translate acidic molecules on the tongue into a neural signal th...MIT, BU team builds viruses to combat harmful 'biofilms'
... variety of proteins, polysaccharides, and nucleic acids that together with other accumulating materials form an extracellular matrix, or in Lu's words, a slimy layer, that encases the bacteria. Traditional remedies such as antibiotics are not as effective on these bacterial biofilms as they are on free-fl...A compound from olive-pomace oil gets 80 percent slowing down of HIV spread
...aimed at making manitol and maslinic and oleanolic acids programmes more profitable. Whilst manitol is ob... waste water (alpechn) and olive-tree leaves, both acids are extracted from dry olive-pomace oil (orujo) produced at the olive-milling stage during olive oil...MU researchers make discovery in molecular mechanics of phototropism
... Liscum and Pedmale now plan to study which amino acids on NPH3 are reversibly phosporylated and how NPH3 is involved in regulating other processes within plants. ......used to date the DNA. He also analysed their amino acids which also change over time. Both datings showed that the insects were at least 450,000 years old. The ice-core researchers are experts at analysing the fine dust which blows onto the ice and is preserved year by year. They advocate two further dat...Prion propagates in foreign host
...hat the yeast prion proteins are rich in the amino acids glutamine and asparagine in the regions of the pro...he fungal prion lacks a rich supply of these amino acids -- a characteristic it shares with the prion-forming protein in mammals, which is otherwise dissimil...JCI Table of Contents -- July 2, 2007
...ts have been shown to target insulin B chain amino acids 923 (insulin B:923), and NOD mice lacking insulin B:923 are protected from diabetes. This suggests that insulin, specifically the insulin B:923 sequence, may be essential for the initiation of spontaneous diabetes in NOD mice. In the July 2 issue o...Doing nature one better: Expanding the genetic code in living mammalian cells
...ategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. In a powerful demonstration of the methods versatility, they then used...Omega-3 fatty acids protect eyes against retinopathy, study finds
Omega-3 polyunsaturated fatty acids protect against the development and progression of...res the potential benefit of dietary omega-3 fatty acids in protecting against the development and progression of retinal disease. The study gives us a bette...New compound effectively treats fungal infections
...r RNA into protein by stitching together the amino acids in the order specified by the message. This requires the help of molecules called tRNAs, which link the code of the messenger RNA to the correct amino acid. Leucyl-tRNA synthetase is one of a group of enzymes called aminoacyl-tRNA synthetases that a...JCI table of contents: June 21, 2007
Editor's Pick:A diet rich in omega-3 fatty acids may lower prostate cancer genetic risk A diet rich in omega-3 polyunsaturated fatty acids found in certain fish or fish oil, nuts, seeds, and vegetable oils may help lower prostate cancer ri...Scientists ponder plant life on extrasolar Earthlike planets
...o think it would be comprised of the same 20 amino acids that we have on Earth. Its intriguing to speculate, and I think well know more when we get more clues....Weizmann Institute scientists develop a general 'control switch' for protein activity
...ng, the scientists insert a short segment of amino acids into the amino acid sequence making up the protein. This segment is capable of binding strongly and selectively to a particular chemical drug, which affects the activity level of the engineered protein by increasing or reducing it. When the drug is n...