Abnormal fat metabolism underlies heart problems in diabetic patients
...articular lipid-digesting enzyme that becomes more active in diabetic heart muscle and contributes to the breakdown of cardiolipin. Recently, Gross and his colleague David Mancuso, Ph.D., member of the division, found that mice engineered to produce too much of this enzyme in their hearts developed defects...New system of wastewater treatment could reduce the size of treatment plants by half
... shorten the water clarification process (by which active mud is separated), eliminating the stage known as ...hich could make it possible to separate water from active mud by a membrane filtration process. This researched and optimized system makes it possible to tr......ine Congress and local legislators. WCS has been active in Patagonia since the 1960s, conducting studies for the conservation of southern right whales, Magellanic penguins, southern elephant seals and other unique wildlife species. WCS also recently became the owner of Karukinka a protected area of over h...European Science Foundation's Forward Look reaches out beyond the endless frontiers
...gnised the scientific community should play a more active role. In accordance with this approach a new set of selection procedures for Forward Look topics have therefore been adapted to ensure a careful choice, while taking into account their relevance at an international level. Under the realigned proce...News tips from the Journal of Neuroscience
...F-actin cytoskeleton. Expression of constitutively active Pak1 disrupted morphological development of dendrites and axons; neurons did not survive past 7 DIV when Pak1 expression was silenced by RNA interference. 3. Toward an Auditory Midbrain Implant Hubert H. Lim and David J. Anderson Cochlear imp...Role of thyroid hormones in slumber under investigation at Rutgers
..., undergraduate and graduate students will have an active role in this project. ...Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
... development, the embryonic epsilon-globin gene is active first, followed by the gamma-globin genes, and finally the adult form, beta-globin takes control following birth. Understanding how genes are regulated or turned on and off is critical. In gene therapy, a normal gene can be inserted into cells to c...Satellite tracking will help answer questions about penguin travels
...tudies.org. The transmitters will be active for 36 hours at a time and then will be off for 36 hours, a means of preserving the two double-A batteries in each transmitter for the life of the project. The researchers have no way of knowing whether the birds will go to southern Argentina or the ...Identified mechanism in the malaria parasite to help it adapt to infected individuals
...es involved in the invasion of red blood cells are active or inactive in parasites found in nature. Thanks to this study we have been able to identify 7 genes in 4 different genetic families that may be silenced in a specific P. falciparum strain; we suspect, however, that other genes may also be silenced, ...Unlocking proteins from their cellular shell
...ble sites for drugs that might interact with these active proteins to treat disease. The study appears in the current issue of the journal Science. Cells are exposed to forces every minute of every day. Some forces are exerted by the flow of bodily fluids, such as blood streaming through arteries, while o...New strategy for treating allergic disorders
...ed to fight other disorders. There are a number of active substances for the treatment of allergies and auto-immune diseases that scientists suspect are effective in suppressing these diseases. However, it seems to be impossible to introduce these substances into the intestine in an effective manner. Pieter...Marijuana component opens the door for virus that causes Kaposi's sarcoma
PHILADELPHIA The major active component of marijuana could enhance the ability o...otropic part of marijuana, an analog of THC is the active ingredient of marinol, a drug frequently given to AIDS patients, among others, for increasing appet...Einstein researchers' prototype vaccine could provide improved protection against tuberculosis
...ug resistant TB and growing numbers of people with active TB due to coinfection with HIV, the advance could ... worlds population (up to 10% of whom will develop active TB) and causes up to three million deaths annually. The only available vaccine--known as Bacille Ca...Handicapping tuberculosis may be the way to a better vaccine
...oping countries. Most TB is latent, but can become active when the immune system is weak, such as during HIV infection, and more than 1.6 million die each year from this disease. In addition, resistance to current treatments is becoming increasingly common, making an effective vaccine all the more crucial. ...JCI table of contents: August 1, 2007
...ses, integrated near the 5" ends of genes that are active in the treated cell population. Although the diver...the sites detected remained at the 5" end of genes active in the cell populations analyzed. Importantly, the retrovirus integration sites observed in cells fr...Negative effects of plastic's additive blocked by nutrient supplements
...that administration of folic acid or genistein, an active ingredient in soy, during pregnancy protected the ... is readily available in health food stores, is an active ingredient in soy. It is possible, Jirtle said, that the reason Asians have much lower rates of obes...Study identifies new gene therapy tools for inherited blindness
...further studies of the grammar of regulatory sites active in photoreceptor cells, Corbo and others are currently using the results of the study to design gene therapy vectors for a form of Leber's congenital amaurosis, an inherited disorder that leaves patients blind from birth....Call for EU to launch major project to map out all our proteins
Biologists still have no clear idea how many active genes there are coding for proteins in humans and other organisms, even though for some species the genomes have been completely sequenced. This is because many of the genes and their protein products have only been predicted by computer algorithms t...Researchers watch antibiotics, bacteria meet at atomic level
...ymerase from T. thermophilus. They then created an active elongation complex by mixing the enzyme with small molecules of DNA and RNA. This solution hardened into a crystal, which the researchers could then examine using an imaging technique called X-ray crystallography. X-ray crystallography let them cre...Adult survivors of childhood leukemia exercise less, worsening high risk for obesity and illness
...ult survivors of childhood ALL are less physically active than the general U.S. population, the team reports... providers to develop plans for healthier and more active lifestyles. Research shows that physical activity can undo risk caused by treatment, said senior ...