PET/CT should be 'first-step' test for patients with Crohn's disease
..."PET/CT can answer the major question: What is the activity of the disease"" explained Hustinx. Crohn's dise...uate between periods of inactivity (remission) and activity (relapse). During relapses, symptomsvarying in nature, frequency and intensityinclude abdominal pain...PET/CT: The best test for women with ovarian cancer
... information about the body's chemistry, metabolic activity and body function, while CT supplies anatomic images. ......and Christopher Honey find the 98 percent of brain activity that other researchers consider just background no... at rest. In this "resting state," waves of neural activity ripple through the brain, creating fluctuating and ever-changing patterns. Sporns and Honey's work o...Depiction of findings selected as '2007 Image of the Year' by Society for Nuclear Medicine
... she added. The researchers assessed brain MAO A activity in 27 healthy, non-violent male volunteers using p...e main finding: The lower the subjects brain MAO A activity levels, the more they answered yes to statements about taking advantage of others, causing them disc...Michael R. Zalutsky receives SNM's 2007 Paul C. Aebersold Award
...t are addressed include maintaining the biological activity of the molecule, radiation safety and cost effectiveness. The radiolabeling facility assists the centers members in the preparation of investigational new drug applications to the Food and Drug Administration to permit clinical investigation of promi...PET accurately identifies esophageal cancer patients' positive responses to chemotherapy
...er proceduresabout the body's chemistry, metabolic activity and body function. ...New insights into the neural basis of anxiety
...ues." Using a new technique to switch off neural activity in selective brain cells in living mice, Gross and his colleagues discovered that a specific part of the hippocampus is required for correct processing of ambiguous stimuli. "Shutting down a specific circuit in the hippocampus abolished fear reacti...Genomic signatures identify targeted therapies for lung cancer
...led oncogenes, set off a cascade of changes in the activity of hundreds of other interacting genes -- either increasing or decreasing their activity. Rather than looking at each of these oncogenes individually, this new method presents a more global view by identifying the pathway encompassing all of the ge...Cellular message movement captured on video
...ptly from hubs of communication and transportation activity on the cell surface toward the nucleus. Paxillin w...rimarily at focal adhesions, busy intersections of activity scattered around the cells cytoplasmic membrane. Focal adhesions are regions rich with receptors for...Cells re-energize to come back from the brink of death
...a molecule called cytochrome c, which triggers the activity of enzymes called caspases. In turn, caspases trig...functioning of the mitochondria and triggering the activity of certain genes that prevent or repair cell damage. The findings also suggest that the increase in ...Cold Spring Harbor Protocols features methods to understand embryos, clones, stem cells
...nt. These epigenetic marks are indicative of gene activity (off versus on), and can be used to understand processes underlying normal development, cellular reprogramming, and even events leading to cancer and other disease states. One of the protocols, freely available at http://www.cshprotocols.org/cgi/...Existence of muscle-building stem cells points to regenerative therapies for muscular disease
...ellite cells consist of two classes defined by the activity or inactivity of a gene called Myf-5. Moreover, that genetic difference gave rise to an important distinction in the satellite cells behavior. Cells without active Myf-5 divide asymmetricallya characteristic commonly seen among stem cells. That lop...Natural compound and exercise boost memory in mice
...portant for learning and memory, and decreased the activity of genes playing a role in inflammation and neurodegeneration. The researchers found that sedentary mice fed epicatechin showed enhanced memory, blood vessel growth, and gene activity, but these benefits were even more evident in mice that also ex...News tips from the Journal of Neuroscience
... Herry et al. show that unpredictability increases activity in the amygdala, the brains fright center, regardless of the stimulus. Mice presented with unpredictably timed neutral sound pulses showed greater c-Fos expression in the basolateral amygdala (BLA) compared with those that received predictable stimul...Avian influenza survivors' antibodies effective at neutralising H5N1 strain
...eless, we are encouraged by the broad neutralizing activity of these antibodies in the lab and the moderate doses required." Using administered antibodies has a historical precedent. During the 1918 Spanish H1N1 influenza pandemic, there were multiple reports of physicians administering blood taken from sur...Story ideas from the Journal of Biological Chemistry
.... Curcumin was previously shown to have anti-tumor activity but its effects on the immune system were unknown until now. Gaurisankar Sa and colleagues showed that curcumin boosts the immune system of tumor-bearing mice by restoring key immune cells called CD4 and CD8 T cells. The scientists also showed tha...MIT-led team uncovers malaria mechanism
...'s work and form research partnerships. This GEM4 activity is supported by a number of institutions, including the National Science Foundation. Multidisciplinary, multinational research at the intersections of engineering, life sciences and medicine, with major implications for public health is "exactly wh...Fragile X syndrome -- A stimulating environment restores neuronal function in mice
...tic strength, but this requires increased neuronal activity to occur."...New genetic data overturn long-held theory of limb development
...the team inserted molecular markers and showed the activity pattern has similarities to patterns of these same...n paddlefish, which reveals that a pattern of gene activity long thought to be unique to vertebrates with hands and feet is in fact much more primitive. This is...Long-term ulcerative colitis study shows Remicade responders maintained improvement
...PGA score of 0 or 1, and 41 percent had no disease activity (PGA score of 0). At week 56, 92 percent of those ...that rapidly reduces UC symptoms and keeps disease activity at bay over time may reduce the impact of the disease on patients' work status and productivity." ...