Researchers uncover protection mechanism of radiation-resistant bacterium
...individuals are treated for exposure to chronic or acute doses of radiation; could lead to ways to protect cancer patients from the toxic effects of radiation therapy; and may prove significant in efforts to contain toxic runoff from radioactive Cold War waste sites. Fifty years ago, scientists discovere...News tips from the Journal of Neuroscience
...arated monkeys. GUCY1A3 expression correlated with acute and long-term self- and social-comforting behaviors. Whether GUCY1A3 is simply a marker of this behavior or plays a causal role remains to be determined. 3. Input Fluctuations in Layer 5 Pyramidal Neurons Maura Arsiero, Hans-Rudolf Lscher, Brian ...Why is long-term therapy required to cure tuberculosis?
...has been found in other bacterial infections, both acute and chronic," they say. Understanding and countering the ways in which bacteria in general (rather than TB specifically) become resistant to antibiotics, say Ramakrishnan and colleagues, "may hold the key to reducing the duration of treatment of al...Trojan horse strategy defeats drug-resistant bacteria
...n mice, gallium treatment blocked both chronic and acute infections caused by this bacterium. The idea of using gallium as a substitute for iron was developed by a group led by Bradley Britigan, a researcher at the University of Cincinnati and a co-author on this study. The general approach of targeting...$7.9M awarded to UCI stem cell scientists
...hopes of restoring upper limb function impaired by acute and chronic spinal cord injury. Keirstead's laboratory was the first in the world to develop a method to restrict human embryonic stem cells so they generate large amounts of only one cell type in high purity. That type of cell, an oligodendrocyte, i...Study identifies risk factors for spread of respiratory infections in hospitals
The 2003 severe acute respiratory syndrome (SARS) epidemic in China has lessons to teach hospitals on how to prevent the spread of other respiratory diseases, according to new research appearing in the April 15 issue of Clinical Infectious Diseases, currently available on...Gallium: A new antibacterial agent?
...hermore, inhalation of Ga protected mice from both acute and chronic P. aeruginonsa lung infections. As Ga is already FDA approved for the treatment of hypercalcemia of malignancy, these data suggest that Ga might be a promising new therapeutic for the treatment of infection with P. aeruginonsa, a major ca...JCI table of contents: March 15, 2007
...hermore, inhalation of Ga protected mice from both acute and chronic P. aeruginonsa lung infections. As Ga is already FDA approved for the treatment of hypercalcemia of malignancy, these data suggest that Ga might be a promising new therapeutic for the treatment of infection with P. aeruginonsa, a major ca...Stress and nerve cells survival in rats; finding may open window for depression treatment
...oviding a possible time window for treatment after acute episodes of stress," says Henriette van Praag, PhD, of the Salk Institute for Biological Studies. When Peterson and his research team put a young rat in a cage with two older rats for 20 minutes, the resident rats quickly pinned down and, in many c...News tips from the Journal of Neuroscience
... We are all familiar with the immediate effects of acute psychosocial stress on our mood. Now a report from...s et al. this week addresses the impact of such an acute stress on new neurons in the hippocampus. To induce stress, the authors introduced a naive male intr......ber of TB infections. However, the problem is most acute in Africa and Asia where HIV/AIDS is also most prolific and a shortage of traditional TB medicines and problems with patient compliance has led to the emergence of drug-resistant strains of the disease. "There were only ever a limited number of dru...JCI table of contents -- March 8, 2006
...ool, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a p...gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis AUTHOR CONTACT: Stefan Frhling Brigham and Womens Hop...Major gene study uncovers secrets of leukemia
...ions that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children. The discovery not only suggests novel methods for treating pediatric ALL, but also provides a roadmap for the identification of unsuspected mutations in adult cancers. ALL is a tu...CDX2 -- A protein that promotes leukemia
...ool, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells. CDX2 regulates the expression of a number of genes that encode members of the HOX family of proteins, which might provide a new set of targets for the tre...New study suggests special cocoa may lead to sustained improvement in blood vessel function
...y with statins. Previous studies have demonstrated acute or short term improvements in endothelial or blood vessel function after consuming this flavanol-rich cocoa, but this is the first study to suggest that these benefits may build and be sustained over several days - even to the point of apparent rever...Leukemia drug turns mini-molecules up, cancer genes down
...earch shows that a form of vitamin A used to treat acute promyelocytic leukemia induces changes in an unusual class of small molecules called microRNAs (miRNAs) in the leukemic cells. The study also shows that three of these miRNAs inhibit the action of two genes important for cancer development, helping ...News tips from the Journal of Neuroscience
...h progesterone, as well as in mice subjected to an acute stress (2 min of increased CO 2 ). Acute stress increases neurosteroids, and treatment of brain slices with the neurosteroid THDOC (3a,5a-tetrahydrodeoxycorticosterone) also increased tonic GABAergic inhibition. 2. Engineering Astrocytes as Inj...Research physiologists convene for 120th Annual Meeting
...out: forensic medicine biomarkers of acute kidney injury respiratory control in insects the strange life of the six muscles that move the eyeball pharmacogenetics of estrogen and cardiovascular disease and linking noncoding DNA to biology and disease. WHAT IS THE APS? T...The metabolic response to colitis varies depending upon whether inflammation is chronic or acute
...tion of the colon) based on whether the disease is acute (sharp and brief) or chronic (long-term). Research...e model of colitis, discovered that the effects of acute colitis were associated with decreased body weight, food intake, and body fat content. Chronic colit...New imaging technique tracks traffic patterns of white blood cells
...ular level but there is still no treatment for the acute vascular occlusions which are the hallmark of the disease," said Mount Sinai researcher Dr. Paul S. Frenette. "In vivo imaging provides a window inside the body that allows us to see exactly which blood cells and which molecular constituents particip...