Researchers identify potential therapeutic target for Huntington's disease
...t step in progression of the disease. Huntington's affects an estimated 30,000 people in the United States. It is characterized by loss of motor control and cognitive functions, as well as by depression or other psychiatric problems....Joslin Diabetes Center announces new nutrition guidelines
...in a skyrocketing rate of type 2 diabetes that now affects at least 18.2 million Americans, including an increasing number of young people. An estimated 41 million Americans have pre-diabetes and are at risk of developing full-blown type 2 diabetes unless they lose weight and increase physical activity. Diab...Liverpool vet creates pain relief diet for arthritic dogs
...e long-term development of OA in dogs. OA mainly affects larger breeds of dog, such as Labradors, Golden Retrievers and German Shepherds and if left untreated, the debilitating condition can cause severe pain and lameness. Dog owners are sometimes unable to detect signs of OA in their animals, but it is t...'Motherwell's babies' study may yield up clues for adult diseases
...hat growth from the very earliest days in the womb affects health in adulthood, particularly the risks of heart disease, diabetes and osteoporosis. If the mother eats an unbalanced diet this can trigger her body to produce increased amounts of stress hormones, which can then have long term effects on the str...Childhood asthma may be linked to grandmother's smoking
... is that when a pregnant woman smokes, the tobacco affects her fetus's DNA," said Dr. Gilliland. "We speculate that the damage that occurs affects the child's immune system and increases her susceptibility to asthma, which is then passed down to h...Pregnancy complications related to low levels of anticlotting proteins
...20 women with inherited clotting conditions, which affects about 20 percent of Caucasian women. "In early pregnancy, patients with low levels of protein Z have a fourfold higher risk of pregnancy complications," said Paidas. "Based on our data, we speculate that protein S free antigen levels below 29 percent...New Zealand forest giant prevents landslides
...earchers can also use it to calculate how rainfall affects the soil. Waitakere Ranges Waitakere Ranges Regional Park is situated on the North Island of New Zealand. About 1000 years ago this entire island was covered with kauri trees, which can reach a height of 50 metres and grow in the most inhospitabl...Ancient enzyme guides healthy eating in mammals
...reveal that the ancient amino acid-sensing pathway affects feeding behavior by activating a brain circuit that biases consumption against imbalanced food sources, the researchers said. While the findings are in mice, "there's no reason to believe that the same mechanism isn't at work in humans," Ron said. Ho...Jeffrey Friedman, discoverer of leptin, receives Gairdner, Passano awards
...leagues at Rockefeller and Yale showed that leptin affects both the architecture and function of neural circuits in the brain by changing the wiring of the brain, a phenomenon known as plasticity. Leptin alters the wiring by controlling synapses -- the inputs and outputs to neurons that, in this case, regula...Breakthrough in stem cell research
...cause they are destroyed in type-1 diabetes, which affects at least 100,000 people in Australia. So far there is no cure for it. "Human embryonic stem cell research offers a permanent answer to the problem. It gives the hope that we can produce a pure population of those cells in large numbers and transplan...Gene regions beyond protein instructions important in disease
...ch higher than the incidence of the disease, which affects roughly 1 in 5,000 births, on average. The mutation is almost twice as common in Asians as in Europeans, and a study in the 1980s showed that Asian Americans in California were twice as likely to have a child with Hirschsprung disease than mothers of...JCI table of contents May 1, 2005
...reast cancer. TITLE: Adipocyte-derived collagen VI affects early mammary tumor progression in vivo: Interaction in the tumor/stroma microenvironment AUTHOR CONTACT: Philipp E. Scherer Albert Einstein College of Medicine, Bronx, NY USA Phone: 718-430-2928; Fax: 718-430-8574; E-mail: scherer@aecom.yu.edu Vie...Reducing specific gene levels makes breast cancer cells more responsive to ionizing radiation
...mal breast milk-duct cells. "Since BRCC36 directly affects BRCA1 and BRCA1 is activated after exposure to radiation, we wanted to see if BRCC36 might be important in this response," said Xiaowei Chen, Ph.D., a Fox Chase postdoctoral researcher in the laboratory of geneticist Andrew K. Godwin, Ph.D., and the ...... research has been done on how "fear-conditioning" affects brain circuitry, but what about the flip side: "safety conditioning?" Now, researchers led by Michael T. Rogan and Eric R. Kandel of Columbia University Medical Center have discovered in mice how the brain responds to external stimuli that signal saf...Study finds enzyme activity promotes rare form of leukemia, offers potential target for new drugs
...curable acute myeloid leukemia (AML). This disease affects less than 2 percent of the estimated 16,000 individuals diagnosed with acute leukemia nationwide each year. The discovery, based on research using bone marrow cells from mice, offers a potential target for new drugs against this form of leukemia, the...... depletion. It providesa comprehensive look at the affects of floods, droughts and pollution by various sources, and shows howwater resources are protected through conservation, water quality treatment, and protective laws andlegislation. Produced in cooperation with the Bureau of Reclamation, the National P...Faulty body clock leads to obesity and diabetes
... you eat but what time of day you eat and how that affects the body. Are you eating at a time of day when your system is internally aligned to metabolize the food?" Approximately 18 million people in the United State have diabetes and nearly two-thirds of adults are overweight, which includes 30 percent who...Brain scans reveal how gene may boost schizophrenia risk
...al illness marked by hallucinations and delusions, affects one percent of the population and is treated with antipsychotic drugs that block dopamine. The prefrontal cortex is critical for motivation, learning in response to reward, and working memory functions impaired in schizophrenia, which is thought to ...Glaciers from Antarctic peninsula in widespread retreat, Science study says
...hers may use the maps to study how glacier retreat affects phytoplankton and sea edge communities. Nations interested in building research stations in Antarctica could consult the maps so as to avoid building near glaciers that have acted with the highest variability in the last 50 years....Cleaner shrimp use rocking dance to advertise their service to clients
... cleaner shrimp, performs a specialized dance that affects the behavior of large, predatory client fish. This signaling represents shrimp-to-fish communication that allows both hungry cleaner shrimp and parasite-laden client fish to benefit from a non-predatory, "cleaning" interaction. The cleaner-client re...