Tag: "agent" at biology news
Oncolytics Biotech Inc., research collaborators demonstrate reovirus/gemcitabine
...s in control groups or tumours treated with either agent
alone. The researchers concluded that the synergistic combination of REOLYSIN and gemcitabine is a promising therapeutic regimen for study in clinical trials. "It is rare to see the virtual elimination of tumours as well as the long-lasting therap...
Cetuximab and irinotecan combination increases survival in metastatic colorectal cancer
...se in side effects, cetuximab is a key therapeutic agent
in the optimal treatment of advanced colorectal cancer." The EPIC trial was designed to study the overall survival in patients treated with both cetuximab and irinotecan, with secondary objectives that include response rate and progression-free sur...
Cetuximab increases survival in advanced colorectal cancer patients, study shows
...air of the study. "This is the first time a single agent
biologically targeted therapy has demonstrated a survival advantage in patients with colorectal cancer, and it is also the first time an EGFR-targeting drug has achieved this goal." Conducted by the National Cancer Institute of Canada Clinical Tria...
Enhancing chemotherapy's efficacy: New agent has synergistic effect with standard drugs
...dict that MCP110 is a potentially useful treatment agent
for combination chemotherapy."In addition to Khazak and Golemis, co-authors include Fox Chase visiting scientist Natalia Skobeleva, Ph.D., of St. Petersburg Polytechnical Institute in St. Petersburg, Russia, NexusPharma chemistry director Sanjay Meno...
Oncolytics Biotech Inc. proceeds to initiate US Phase II sarcoma clinical trial
... trial (REO 014) is a Phase II, open-label, single agent
study whose primary objective is to measure tumour responses and duration of response, and to describe any evidence of antitumour activity of intravenous, multiple dose REOLYSIN in patients with bone and soft tissue sarcomas metastatic to the lung. ...
Presidential Recognition Awards presented at the 2007 AIUM Annual Convention
...y provided towards the goal of ultrasound contrast agent
approval in the US. This prestigious award hono...tration's review and ultimate approval of contrast agent
use in the United States. The members of the AIUM Contrast Ultrasound Team include Peter Burns, MD, ...
Little lifesavers -- Nanoparticles improve delivery of medicines and diagnostics
...mmediately self-assemble onto the drug and imaging agent
cluster to form a coating with the hydrophobic portion attached to the nanoparticle core and the hydrophilic portion stretching out into the water. By carefully adjusting the concentrations of the substances, as well as the mixing speed, the research...
Disease can be our ally, not just our enemy, says new book by UCR evolutionary biologist
...of a disease agent, or they can be produced by the agent
itself as part of an effort to spread to other hosts. You want to encourage the former and squelch the latter. Take fever, for instance. Animals allowed to raise their body temperatures through fever recover more quickly than those given fever-red...
Better together: Bacterial endosymbionts are essential for the reproduction of a fungus
...rhizoxin, which has been shown to be the causative agent
in rice seedling blight. The researchers now report a second, striking benefit conferred on the fungus by its intracellular symbiont.When the bacteria are eliminated from the fungus with antibiotic treatment, the fungal cells are no longer able to ...
Widely used iron nanoparticles exhibit toxic effects on neuronal cells
...th DMSA (dimercaptosuccinic acid), a metal binding agent
that polymerizes on the particles' surface. This coating keeps the particles from clumping together in an aqueous solution, and facilitates their engulfment by the PC12 cells via an inward pouching of the cell membrane called endocytosis. What happen...
Stem cell therapy shows promise for rescuing deteriorating vision
...lls as a continuous delivery system" to shuttle an agent
known as glial cell line-derived neurotrophic factor or GDNF, Lund explains. "It's not a sensible thing to inject the eyes many times over years. The idea was to use the cells as a continuous delivery system, but we found they work quite well on thei...
ACS News Service Weekly PressPac -- March 21, 2007
...nglass lenses change color on demand MRI contrast agent
can detect killer plaques in heart disease Toward..., March 27, 8:00 p.m., Central Time MRI contrast agent
can detect killer plaques in heart disease A new bright spot in heart disease research may soon al...
Migratory birds: Innocent scapegoats for the dispersal of the H5N1 virus
...n movements of domestic poultry have been the main agent
of global dispersal of the virus to date. The occurrence of an outbreak at a commercial turkey farm in Suffolk, England, in February 2007 fits this wider pattern. Wild birds, particularly waterfowl, are a key element of the viral ecology of low pa...
Targeting tumors the natural way
...ural antibodies and immune responses. "The killing agent
we chose is already in us," says UW-Madison chemis...esearch. In contrast, an established tumor-homing agent
linked to the cell toxin doxorubicin destroyed cells even when they expressed very little integrin, ...
30th anniversary of the Heinz Maier-Leibnitz Prize
...y, Ludwig-Maximilians University, Munich The key agent
for the production of proteins is ribonucleic acid (RNA): it copies the blueprint for a protein in the cell nucleus and serves as a template for the assembly of the individual parts of the target protein in the cytoplasm. Things become dangerous when...
Will the plague pathogen become resistant to antibiotics?
...se plague is often fatal, Y. pestis is a potential agent
for bioterrorism. There is no vaccine, but antibio...ata imply that high levels of MDR in the causative agent
of plague may rapidly evolve naturally, and present a vital biomedical, public health, and biodefens...
New sensor detects gaseous chemical weapon surrogates in 45 seconds
...tional Laboratory have developed a chemical weapon agent
sensing technique that promises to meet or exceed ...emonstrated QPAS's ability to detect gaseous nerve agent
surrogates. In one test, researchers used diisopropyl methyl phosphonate (DIMP), which is a chemical...
Tips from the Journals of the American Society for Microbiology
...act of chickens that may serve as an antimicrobial agent
against food-borne pathogens. They report their findings in the March 2007 issue of the journal Antimicrobial Agents and Chemotherapy. Food-borne pathogens, responsible for most cases of food poisoning in developed countries, are commonly affiliat...
Mechanisms involved with tumor relapse identified
...juvants are agents that are able to modify another agent
basically working as a chemical catalyst....
Anti-fungal drug kills TB bug
...ave shown that chemicals called azoles the active agent
in many antifungal drugs kill the TB bacteria, an...d by fungi such as Candida albicans (the causative agent
of thrush). "The class of drugs called azoles are able to kill off fungal infections by blocking t...
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