Fox Chase Cancer Center scientists identify immune-system mutation
...m bone marrow) generate antibodies against foreign agents that enter the body. Other T cells are known as killer cells because they attack foreign invaders more directly. "The maturation of T cells involves key branch points at which cells choose one of two different pathways, going on to become helper cel...2005 ASM biodefense research meeting
...sentation topics include: Prions as novel threat agents Protecting the food supply from agroterrorism Bird flu and pandemic flu preparedness The press center will be located in the Baltimore Marriott Waterfront Hotel. Program and abstract books, news releases and information about daily activities will...Licorice licks herpes virus infection
... opportunity for developing novel anti-herpesvirus agents to control, and perhaps eradicating latent viral infections. In an accompanying commentary, Jeffrey Cohen states, "a compound present in licorice may seem like an unlikely candidate for the treatment of virus-associated cancersderivates of GA might b...JCI table of contents March 1, 2005
... opportunity for developing novel anti-herpesvirus agents to control, and perhaps eradicating latent viral i...e brain, or some other organ. The most widely used agents to promote angiogenesis are growth factors known as VEGF and FGF. However, in clinical settings, th...Boosting blood vessels with BDNF
...e brain, or some other organ. The most widely used agents to promote angiogenesis are growth factors known as VEGF and FGF. However, in clinical settings, these have only been able to form new and stable blood vessels for a limited time. VEGF may also cause abnormal vascular leaks and aberrant masses of b...Research may provide ways to inhibit cancer's ability to resist treatments
...reak ends. Without it, cells are more sensitive to agents such as ionizing radiation or certain drugs that kill cells by damaging their DNA. DNA, or deoxyribonucleic acid, is a large molecule shaped like a double helix found primarily in the chromosomes of the cell nucleus and contains the genetic informati...TAT2005 - 3rd International Symposium on Targeted Anticancer Therapies
...e new generation of rationally designed anticancer agents with well defined molecular targets in the cancer ...er patients. In addition, dozens of other targeted agents are in various stages of clinical development. It is expected that several of these agents will obta...New way to make human embryonic stem cell therapy safer
...se, hepatitis B or C viruses, and other infectious agents can be transmitted from human donor cells to the recipient. Similarity, co-culture of human embryos with live animal cells causes concern for infection with recognised or as yet unrecognised infectious agents. We derived and established new human emb...Could microbes solve Russia's chemical weapons conundrum?
... the world's largest stockpile of chemical warfare agents (CWAs). The country faces a race against time to dispose of the stockpile by 2007, in accordance with the Chemical Weapons Convention (CWC). This disposal must be achieved in an ecologically-sound manner. Dr. Inna Ermakova and colleagues from the GK ...Study: Soap and water work best in ridding hands of disease viruses
... studied the efficacy of 14 different hand hygiene agents in reducing bacteria and viruses from the hands," ...er realistic conditions," she said. Anti-microbial agents were best at reducing bacteria on hands, but waterless, alcohol-based agents had variable and someti...Defensins neutralize anthrax toxin
...although it is not clear when new chemotherapeutic agents on the basis of defensins will be available. The researchers, however, hope that a drug against anthrax toxin can be ready for human use within the next years. Anthrax causes an infectious disease mostly in pigs, cattle, horses, sheep and goats. The ...Harnessing microbes, one by one, to build a better nanoworld
...ar-instantaneous detection of dangerous biological agents such as anthrax. The approach, reported here today...her public areas to sniff for dangerous biological agents that might be used in a bioterror event. The device could be constructed, according to Beck, utilizi...Highlights of chemical society national meeting in San Diego, March 13-17
...any antibiotics, immunosuppressants and anticancer agents are based on a class of natural compounds called polyketides, small but complex molecules produced in bacteria and fungi in tiny amounts. Limited yields from natural sources and the difficulty of making them synthetically has limited their supply and...Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
... 20 years it has been the chemist's job to develop agents that can be used to enhance MRI contrast," said Eric Ahrens, assistant professor of biological sciences in the Mellon College of Science at Carnegie Mellon. "Now, with our approach, we have put this job into the hands of the molecular biologist. Usin...Scientists discover that host cell lipids facilitate bacterial movement
...n the door to using PI3-kinase inhibitors or other agents that lower PIP2 and PIP3 levels to slow the spread of Listeria and control infection in patients who are not responding to antibiotics, although that application is a long way off, says Dr. Southwick....Scientists solve structure of key protein in innate immune response
... companies have tried to develop anti-septic shock agents for a long time without clear success," explains Dr. Lee. "Since LPS is an important inducer of septic shock, blocking LPS receptors such as CD14 are among the most important targets. Our structure shows the shape of the LPS binding pocket of CD14. N...Breath may help diagnose infection
...er colleagues exposed pigs to different infectious agents and collected breath samples, which they condensed...ne markers which appear as a result of exposure to agents should be absent in uninfected populations," says Jackman. To determine whether the cytokine levels...Antibodies from plants protect against anthrax
...horities to treat individuals exposed to bioterror agents such as anthrax," says Les Baillie of the Naval Medical Research Center. Dr. Baillie, who is also associated with the University of Maryland Biotechnology Institute, conducted his research in collaboration with Dr. Vidadi Yusibov, Director of the Fra...Researchers discover molecule that causes secondary stroke
...ies in rats, the team measured each of the suspect agents in 12 hemorrhagic stroke patients. Within 10 days, four of the group suffered a secondary cerebral vasospasm. The same patients were also found to have elevated levels of bilirubin and significantly higher levels of BOXes. One of the 12 who had elev......tial effectiveness of treating tumors by combining agents that damage DNA with a drug that sensitizes cancer...further studies continue. "The use of DNA-damaging agents has revolutionized chemotherapy against a wide variety of cancers," says Dr. Thomas. "However, a nar...